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I-kappaB kinase epsilon Dmel_CG2615
Protein found in Drosophila melanogaster
IKKepsilon-PC
CG2615 gene product from transcript CG2615-RC
IKKepsilon
CG2615-PB
IKKepsilon-PB
IKK-related kinase
CG2615-PC
I-kappaB kinase epsilon
apoptoxin 7
lethal (2) 38Ea
ik2
IkappaB kinase-like 2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3Y8
part of
Ubiquitin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3Y8
Protein kinase-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3Y8
Protein kinase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase, ATP binding site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3Y8
encoded by
IKKepsilon
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3Y8
molecular function
protein kinase activity
determination method
IEA
NAS
2 references
retrieved
8 April 2019
stated in
Protein kinases and phosphatases in the Drosophila genome
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IEA
protein serine/threonine kinase activity
determination method
IDA
1 reference
retrieved
16 July 2018
stated in
IKKε regulates cell elongation through recycling endosome shuttling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Y8&geneProductId=UniProtKB:Q9V3Y8
determination method
IDA
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
A transport and retention mechanism for the sustained distal localization of Spn-F-IKKε during Drosophila bristle elongation
GOA
curator
UniProt
UniProt protein ID
Q9V3Y8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IPI
retrieved
8 April 2019
stated in
The Drosophila IKK-related kinase (Ik2) and Spindle-F proteins are part of a complex that regulates cytoskeleton organization during oogenesis
GOA
curator
UniProt
UniProt protein ID
Q9V3Y8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IPI
retrieved
8 April 2019
stated in
Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IPI
ATP binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IEA
kinase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V3Y8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IEA
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V3Y8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IEA
protein serine/threonine kinase activity
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
IKKε regulates cell elongation through recycling endosome shuttling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IBA
cell component
cytoplasm
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
IKKε regulates cell elongation through recycling endosome shuttling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IDA
cell tip
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
IKKε regulates cell elongation through recycling endosome shuttling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IDA
biological process
cell morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IMP
microtubule bundle formation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Asymmetric microtubule function is an essential requirement for polarized organization of the Drosophila bristle
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IMP
protein phosphorylation
determination method
IEA
NAS
2 references
retrieved
8 April 2019
stated in
Protein kinases and phosphatases in the Drosophila genome
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IEA
actin filament organization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IMP
oocyte anterior/posterior axis specification
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Drosophila oocyte polarity and cytoskeleton organization require regulation of Ik2 activity by Spn-F and Javelin-like
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IMP
cell death
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IMP
chaeta morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Asymmetric microtubule function is an essential requirement for polarized organization of the Drosophila bristle
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IMP
phosphorylation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V3Y8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IEA
neuron remodeling
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IMP
peptidyl-serine phosphorylation
determination method
IDA
1 reference
retrieved
16 July 2018
stated in
IKKε regulates cell elongation through recycling endosome shuttling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Y8&geneProductId=UniProtKB:Q9V3Y8
determination method
IDA
endocytic recycling
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
IKKε regulates cell elongation through recycling endosome shuttling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IMP
maintenance of epithelial integrity, open tracheal system
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IMP
protein trans-autophosphorylation
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
IKKε regulates cell elongation through recycling endosome shuttling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IDA
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IMP
sensory organ precursor cell division
determination method
IGI
1 reference
retrieved
8 April 2019
stated in
Temporal regulation of Drosophila IAP1 determines caspase functions in sensory organ development.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IGI
innate immune response
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Y8&geneProductId=UniProtKB:Q9V3Y8
determination method
IBA
regulation of cytoskeleton organization
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
The Drosophila IKK-related kinase (Ik2) and Spindle-F proteins are part of a complex that regulates cytoskeleton organization during oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IPI
actin filament bundle organization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
IKKε regulates cell elongation through recycling endosome shuttling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IMP
peptidyl-serine phosphorylation
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
IKKε regulates cell elongation through recycling endosome shuttling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Y8
determination method
IBA
has part(s)
protein kinase, ATP binding site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3Y8
protein kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3Y8
Identifiers
RefSeq protein ID
NP_610048
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
35329
NP_724278
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
35329
UniProt protein ID
Q9V3Y8
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3Y8
Ensembl protein ID
FBpp0307790
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0307790
FBpp0080920
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0080920
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