(Q29819672)

http://www.ebi.ac.uk/interpro/protein/Q9W4S7

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

DNA-binding transcription factor activity

ISS

1 reference

9 May 2019

Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

7 references

9 May 2019

Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

9 May 2019

The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

9 May 2019

A protein interaction map of Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

9 May 2019

A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

9 May 2019

Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

9 May 2019

The Drosophila F box protein archipelago regulates dMyc protein levels in vivo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

9 May 2019

The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

sequence-specific DNA binding

IPI

1 reference

9 May 2019

Drosophila Low Temperature Viability Protein 1 (LTV1) Is Required for Ribosome Biogenesis and Cell Growth Downstream of Drosophila Myc (dMyc)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

protein dimerization activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

ubiquitin-specific protease binding

IEA

1 reference

9 May 2019

The Drosophila ubiquitin-specific protease Puffyeye regulates dMyc-mediated growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IPI

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

DNA-binding transcription activator activity, RNA polymerase II-specific

IBA

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

8 April 2019

Target of Rapamycin Complex 2 regulates cell growth via Myc in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

8 April 2019

The Drosophila ubiquitin-specific protease Puffyeye regulates dMyc-mediated growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

1 reference

9 May 2019

Myc localizes to histone locus bodies during replication in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

protein-containing complex

1 reference

9 May 2019

A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

9 May 2019

The Drosophila ubiquitin-specific protease Puffyeye regulates dMyc-mediated growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

9 May 2019

Target of Rapamycin Complex 2 regulates cell growth via Myc in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

transcription, DNA-templated

IBA

biological process

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W4S7&geneProductId=UniProtKB:Q9W4S7

regulation of transcription, DNA-templated

IEA

3 references

27 March 2018

Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W4S7&geneProductId=UniProtKB:Q9W4S7

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W4S7&geneProductId=UniProtKB:Q9W4S7

27 March 2018

Myc and Max homologs in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W4S7&geneProductId=UniProtKB:Q9W4S7

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

transcription by RNA polymerase I

IEA

1 reference

9 May 2019

Max-independent functions of Myc in Drosophila melanogaster.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

cell population proliferation

1 reference

9 May 2019

Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

embryo development ending in birth or egg hatching

IEP

1 reference

9 May 2019

Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

embryonic pattern specification

IEP

1 reference

9 May 2019

A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

Myc-driven overgrowth requires unfolded protein response-mediated induction of autophagy and antioxidant responses in Drosophila melanogaster

IGI

regulation of autophagy

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

1 reference

9 May 2019

The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

1 reference

9 May 2019

A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

cell competition in a multicellular organism

IGI

3 references

9 May 2019

Drosophila myc regulates organ size by inducing cell competition.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

9 May 2019

dMyc transforms cells into super-competitors.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

9 May 2019

dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

dMyc expression in the fat body affects DILP2 release and increases the expression of the fat desaturase Desat1 resulting in organismal growth

response to starvation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

regulation of apoptotic process

1 reference

9 May 2019

Induction of apoptosis by Drosophila Myc.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

regulation of imaginal disc-derived wing size

1 reference

9 May 2019

Dissecting the mechanisms of Notch induced hyperplasia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

positive regulation of imaginal disc growth

1 reference

9 May 2019

dMyc expression in the fat body affects DILP2 release and increases the expression of the fat desaturase Desat1 resulting in organismal growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

negative regulation of Notch signaling pathway

1 reference

1 January 2018

A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W4S7&geneProductId=UniProtKB:Q9W4S7

regulation of organ growth

IGI

1 reference

9 May 2019

Drosophila myc regulates organ size by inducing cell competition.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

positive regulation of developmental growth

1 reference

9 May 2019

Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

positive regulation of neurogenesis

1 reference

9 May 2019

Adult neurogenesis in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

1 reference

9 May 2019

dMyc expression in the fat body affects DILP2 release and increases the expression of the fat desaturase Desat1 resulting in organismal growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

regulation of trehalose metabolic process

1 reference

9 May 2019

dMyc expression in the fat body affects DILP2 release and increases the expression of the fat desaturase Desat1 resulting in organismal growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

cellular response to insulin stimulus

1 reference

9 May 2019

Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

insulin receptor signaling pathway

1 reference

9 May 2019

Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

cellular response to nutrient

1 reference

9 May 2019

Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

positive regulation of multicellular organism growth

1 reference

9 May 2019

dMyc expression in the fat body affects DILP2 release and increases the expression of the fat desaturase Desat1 resulting in organismal growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

positive regulation of growth

1 reference

9 May 2019

Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

positive regulation of transcription by RNA polymerase II

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W4S7

Myc-type, basic helix-loop-helix (bHLH) domain

IBA

has part(s)

1 reference

stated in

InterPro Release 71.0