(Q29820549)

English

Rad50 Dmel_CG6339

Protein found in Drosophila melanogaster

CG6339-PD
rad50
CG6339 gene product from transcript CG6339-RE
rad50-PE
CG6339-PE
rad50-PD

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

DNA repair protein Rad50, eukaryotes

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9W252

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9W252

RAD50, zinc hook, protein family

1 reference

based on heuristic

inferred from protein domain or family

Rad50/SbcC-type AAA domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

single-stranded DNA endodeoxyribonuclease activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

double-stranded DNA binding

determination method

1 reference

8 April 2019

Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

double-stranded telomeric DNA binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

DNA helicase activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

adenylate kinase activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

3'-5' exonuclease activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

ATPase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

single-stranded telomeric DNA binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

G-quadruplex DNA binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

condensed chromosome

determination method

1 reference

8 April 2019

The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

condensed nuclear chromosome

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

site of double-strand break

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

determination method

3 references

8 April 2019

The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

biological process

telomere maintenance via recombination

determination method

1 reference

21 June 2018

The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W252&geneProductId=UniProtKB:Q9W252

determination method

telomere maintenance

determination method

3 references

8 April 2019

The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

8 April 2019

The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage.

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

double-strand break repair via homologous recombination

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W252&geneProductId=UniProtKB:Q9W252

determination method

determination method

2 references

double-strand break repair

determination method

1 reference

8 April 2019

Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

telomere maintenance via telomerase

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

reciprocal meiotic recombination

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W252&geneProductId=UniProtKB:Q9W252

determination method

protein localization

determination method

1 reference

8 April 2019

The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

telomere capping

determination method

1 reference

21 June 2018

The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W252&geneProductId=UniProtKB:Q9W252

determination method

DNA duplex unwinding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

nucleotide phosphorylation

determination method

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W252&geneProductId=UniProtKB:Q9W252

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

chromosome organization involved in meiotic cell cycle

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

nucleic acid phosphodiester bond hydrolysis

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W252&geneProductId=UniProtKB:Q9W252

determination method

cellular response to DNA damage stimulus

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

nucleoside monophosphate phosphorylation

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

nucleic acid phosphodiester bond hydrolysis

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W252

determination method

RAD50, zinc hook

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9W252

Rad50/SbcC-type AAA domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9W252

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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