(Q30009429)

21 May 2017

title

SUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1. (English)

1 reference

21 May 2017

1 reference

Yingying Qu

1

1 reference

21 May 2017

Qin Chen

2

1 reference

21 May 2017

Xueping Lai

3

1 reference

21 May 2017

Changhong Zhu

4

1 reference

21 May 2017

Cheng Chen

5

1 reference

21 May 2017

Xian Zhao

6

1 reference

21 May 2017

Rong Deng

7

1 reference

21 May 2017

Ming Xu

8

1 reference

21 May 2017

Haihua Yuan

9

1 reference

21 May 2017

Yanli Wang

10

1 reference

21 May 2017

Jianxiu Yu

11

1 reference

21 May 2017

Jian Huang

12

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21 May 2017

publication date

29 April 2014

1 reference

21 May 2017

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21 May 2017

volume

13

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21 May 2017

page(s)

95

1 reference

describes a project that uses

21 May 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4021559/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate

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Tumor cell vasculogenic mimicry: from controversy to therapeutic promise

22 May 2017

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Activation of Src and transformation by an RPTPα splice mutant found in human tumours

22 May 2017

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PTEN regulation by Akt-EGR1-ARF-PTEN axis

22 May 2017

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Germline gain-of-function mutations in SOS1 cause Noonan syndrome

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

SUMO: a history of modification

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

SUMO and ubiquitin in the nucleus: different functions, similar mechanisms?

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors

22 May 2017

1 reference

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Modification with SUMO. A role in transcriptional regulation

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

22 May 2017

1 reference

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Signaling through scaffold, anchoring, and adaptor proteins

22 May 2017

1 reference

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Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Molecular Cloning of the Mousegrb2Gene: Differential Interaction of the Grb2 Adaptor Protein with Epidermal Growth Factor and Nerve Growth Factor Receptors

22 May 2017

1 reference

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Phosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

MiRNA-296-3p-ICAM-1 axis promotes metastasis of prostate cancer by possible enhancing survival of natural killer cell-resistant circulating tumour cells

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Grb2 promotes integrin-induced focal adhesion kinase (FAK) autophosphorylation and directs the phosphorylation of protein tyrosine phosphatase α by the Src-FAK kinase complex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Antagonism between binding site affinity and conformational dynamics tunes alternative cis-interactions within Shp2.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

SUMO and its role in human diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

The tyrosine phosphatase Shp2 (PTPN11) in cancer.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Design of peptoid analogue dimers and measure of their affinity for Grb2 SH3 domains.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Ubc9 is essential for viability of higher eukaryotic cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Signalling, cell cycle and pluripotency in embryonic stem cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Role of Grb2 in EGF-stimulated EGFR internalization.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

SUMO, ubiquitin's mysterious cousin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Inhibitors of Ras signal transduction as antitumor agents

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021559

Overproduction of eukaryotic SUMO-1- and SUMO-2-conjugated proteins in Escherichia coli

3 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-13-95

KGF-induced motility of breast cancer cells is dependent on Grb2 and Erk1,2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-13-95

Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-13-95

Grb2 signaling in cell motility and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-13-95

Doxycycline inhibits TGF-beta1-induced MMP-9 via Smad and MAPK pathways in human corneal epithelial cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24775912

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1476-4598-13-95

1 reference

Dimensions Publication ID

1002137675

0 references

1 reference

1 reference

1 reference