(Q58199697)

ORCID Public Data File 2021

author name string

Terrence R Burke

series ordinal

2

0 references

Donald P Bottaro

series ordinal

3

0 references

language of work or name

English

0 references

publication date

August 2008

0 references

published in

Expert Opinion on Therapeutic Targets

0 references

volume

12

0 references

issue

8

0 references

page(s)

1021-33

0 references

cites work

New signals from the invasive front

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Tumor metastasis: mechanistic insights and clinical challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Oncogenic kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Dynamic control of signaling by modular adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

The GRB2/Sem-5 adaptor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Molecular targeting of growth factor receptor-bound 2 (Grb2) as an anti-cancer strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

GRB2: a pivotal protein in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Chromosome locations of genes encoding human signal transduction adapter proteins, Nck (NCK), Shc (SHC1), and Grb2 (GRB2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

KGF-induced motility of breast cancer cells is dependent on Grb2 and Erk1,2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Potentiation of signal transduction mitogenesis and cellular proliferation upon binding of receptor-recognized forms of alpha2-macroglobulin to 1-LN prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Effect of potent and selective inhibitors of the Grb2 SH2 domain on cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Inhibition of tumor metastasis by a growth factor receptor bound protein 2 Src homology 2 domain-binding antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Focal adhesion kinase: in command and control of cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

New concepts regarding focal adhesion kinase promotion of cell migration and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Cadherin switch in tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Matrix metalloproteinases (MMPs) in health and disease: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

The other side of MMPs: protective roles in tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

ADAMs: key components in EGFR signalling and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Meltrin alpha cytoplasmic domain interacts with SH3 domains of Src and Grb2 and is phosphorylated by v-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

ADAM proteases, ErbB pathways and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Met, metastasis, motility and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Grb2 and Nck act cooperatively to promote actin-based motility of vaccinia virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Actin-based motility: from molecules to movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

p21-activated kinases in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

p21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Podosomes as smart regulators of cellular adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

A dynamic podosome-like structure of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Hepatocyte Growth Factor/scatter factor-induces phosphorylation of cortactin in A431 cells in a Src kinase-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Invadopodia: specialized cell structures for cancer invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

An oncogenic epidermal growth factor receptor signals via a p21-activated kinase-caldesmon-myosin phosphotyrosine complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Identification of a novel 135-kDa Grb2-binding protein in osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Regulated association of microtubule-associated protein 2 (MAP2) with Src and Grb2: evidence for MAP2 as a scaffolding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Role of tyrosine residues and protein interaction domains of SHC adaptor in VEGF receptor 3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

The role of mitogen-activated protein kinase activation within focal adhesions in chemotaxis toward FGF-2 by murine brain capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Regulation of endothelial CD44 expression and endothelium-tumour cell interactions by hepatocyte growth factor/scatter factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

How to make tubes: signaling by the Met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

L-selectin activates the Ras pathway via the tyrosine kinase p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

The involvement of selectins and their ligands in tumor-progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Targeting selectins and selectin ligands in inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Short-hairpin RNA-mediated stable silencing of Grb2 impairs cell growth and DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Inhibition of Grb2 and Crkl proteins results in growth inhibition of Philadelphia chromosome positive leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Growth inhibition of breast cancer cells by Grb2 downregulation is correlated with inactivation of mitogen-activated protein kinase in EGFR, but not in ErbB2, cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

The SH2 domain: versatile signaling module and pharmaceutical target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Inhibition of Shc/Grb2 protein-protein interaction suppresses growth of B104-1-1 tumors xenografted in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Investigation of cell cycle arrest effects of actinomycin D at G1 phase using proteomic methods in B104-1-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

8-O-Methylsclerotiorinamine, antagonist of the Grb2-SH2 domain, isolated from Penicillium multicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Development of Grb2 SH2 Domain Signaling Antagonists: A Potential New Class of Antiproliferative Agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Specificity and affinity motifs for Grb2 SH2-ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Phosphotyrosyl mimetics in the development of signal transduction inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Bone marrow stromal cell line co-transfected with IL-2 and IL-3 genes can accelerate restoration of T-cell immunity in allo-BMT mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3'-substituted tyrosine derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Selective GRB2 SH2 inhibitors as anti-Ras therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Grb2 promotes reinitiation of meiosis in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Grb2 regulates Stat3 activation negatively in epidermal growth factor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

A novel viral oncogene with structural similarity to phospholipase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Characterization of the interaction of natural proline-rich peptides with five different SH3 domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Potential disease targets for drugs that disrupt protein-- protein interactions of Grb2 and Crk family adaptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Directed discovery of bivalent peptide ligands to an SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Cell-penetrating SH3 domain blocker peptides inhibit proliferation of primary blast cells from CML patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

High affinity molecules disrupting GRB2 protein complexes as a therapeutic strategy for chronic myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Grb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has antitumor effects in human cancer xenografts alone and in combination with docetaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Design of peptoid analogue dimers and measure of their affinity for Grb2 SH3 domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

UCS15A, a novel small molecule, SH3 domain-mediated protein-protein interaction blocking drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Utilization of a nitrobenzoxadiazole (NBD) fluorophore in the design of a Grb2 SH2 domain-binding peptide mimetic

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

The role of Grb2-associated proteins in T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.8.1021

Inhibition of angiogenesis by growth factor receptor bound protein 2-Src homology 2 domain bound antagonists

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Cell adhesion and signalling by cadherins and Ig-CAMs in cancer

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Shedding of membrane proteins by ADAM family proteases

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Fibroblast growth factor receptor substrate 2 participates in vascular endothelial growth factor-induced signaling

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Antagonists of the Src homology 2 (SH2) domains of Grb2, Src, Lck and ZAP-70.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Potent blockade of hepatocyte growth factor-stimulated cell motility, matrix invasion and branching morphogenesis by antagonists of Grb2 Src homology 2 domain interactions

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

SH3 domains: complexity in moderation

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

A Sos-derived peptidimer blocks the Ras signaling pathway by binding both Grb2 SH3 domains and displays antiproliferative activity

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

30 November 2018

HGF/SF in angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Involvement of hepatocyte growth factor in increased integrin expression on HepG2 cells triggered by adhesion to endothelial cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of Ras.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764957

Grb2 overexpression in nuclei and cytoplasm of human breast cells: a histochemical and biochemical study of normal and neoplastic mammary tissue specimens

30 November 2018

1 reference

12 December 2020

A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor

1 reference

12 December 2020

Structure-activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs

1 reference

12 December 2020

Structure-based design of peptidomimetic ligands of the Grb2-SH2 domain

1 reference

12 December 2020

Significance of the Grb2 and son of sevenless (Sos) proteins in human bladder cancer cell lines

1 reference

12 December 2020

Potent inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands

1 reference

12 December 2020

Involvement of focal adhesion kinase in hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells

1 reference

12 December 2020

Overexpression of the Grb2 gene in human breast cancer cell lines

1 reference

12 December 2020

The Wiskott-Aldrich syndrome

1 reference

12 December 2020

Hypoxia induces activation and subcellular translocation of focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes

1 reference

12 December 2020

Actinomycin D as a novel SH2 domain ligand inhibits Shc/Grb2 interaction in B104-1-1 (neu*-transformed NIH3T3) and SAA (hEGFR-overexpressed NIH3T3) cells

1 reference

12 December 2020

Structure-based design of a non-peptidic antagonist of the SH2 domain of GRB2

1 reference

12 December 2020