(Q30009567)

21 May 2017

title

Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis (English)

1 reference

21 May 2017

0 references

Lisa von Kleist

15

0 references

Emma L Clayton

Emma L Clayton

5

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Mark Robertson

Mark J Robertson

23

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Jennette A Sakoff

Jennette A Sakoff

20

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Frederic A Meunier

Frederic A Meunier

26

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Adam McCluskey

Adam McCluskey

1

0 references

Phillip J. Robinson

Phillip J Robinson

28

0 references

Robert G. Parton

Robert G Parton

18

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James Daniel

James A Daniel

2

0 references

Mark T Howes

Mark T Howes

17

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Michael A Cousin

Michael A Cousin

27

0 references

Ngoc Chau

4

Ngoc Chau

1 reference

21 May 2017

13

Swetha Perera

1 reference

21 May 2017

Gordana Hadzic

3

1 reference

21 May 2017

Anna Mariana

6

1 reference

21 May 2017

Ainslie Whiting

7

1 reference

21 May 2017

Nick N Gorgani

8

1 reference

21 May 2017

Jonathan Lloyd

9

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21 May 2017

Annie Quan

10

1 reference

21 May 2017

Lia Moshkanbaryans

11

1 reference

21 May 2017

Sai Krishnan

12

1 reference

21 May 2017

Megan Chircop

14

1 reference

21 May 2017

Andrew B McGeachie

16

1 reference

21 May 2017

Michael Campbell

19

1 reference

21 May 2017

Xuefeng Wang

21

1 reference

21 May 2017

Jian-Yuan Sun

22

1 reference

21 May 2017

Fiona M Deane

24

1 reference

21 May 2017

Tam H Nguyen

25

1 reference

21 May 2017

publication date

9 October 2013

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21 May 2017

1 reference

21 May 2017

volume

14

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21 May 2017

issue

12

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21 May 2017

page(s)

1272-1289

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The crystal structure of dynamin

21 May 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Crystal structure of nucleotide-free dynamin

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Direct dynamin-actin interactions regulate the actin cytoskeleton

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

HIV enters cells via endocytosis and dynamin-dependent fusion with endosomes

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Comprehensive Mechanistic Analysis of Hits from High-Throughput and Docking Screens against β-Lactamase

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Caveolin regulates endocytosis of the muscle repair protein, dysferlin

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Dynasore, a cell-permeable inhibitor of dynamin

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Cdk5 is essential for synaptic vesicle endocytosis

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Specificity and mechanism of action of some commonly used protein kinase inhibitors

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Development of second-generation indole-based dynamin GTPase inhibitors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Dynamin regulates specific membrane fusion events necessary for acrosomal exocytosis in mouse spermatozoa.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Analysis of synaptic vesicle endocytosis in synaptosomes by high-content screening.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Inhibition of dynamin by dynole 34-2 induces cell death following cytokinesis failure in cancer cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Dynamin inhibitors induce caspase-mediated apoptosis following cytokinesis failure in human cancer cells and this is blocked by Bcl-2 overexpression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Dimeric endophilin A2 stimulates assembly and GTPase activity of dynamin 2

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Regulation of dynamin-2 assembly-disassembly and function through the SH3A domain of intersectin-1s

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

The pthaladyns: GTP competitive inhibitors of dynamin I and II GTPase derived from virtual screening

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

The dynamin inhibitors MiTMAB and OcTMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

The phospho-dependent dynamin-syndapin interaction triggers activity-dependent bulk endocytosis of synaptic vesicles

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Azido and diazarinyl analogues of bis-tyrphostin as asymmetrical inhibitors of dynamin GTPase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Activity-dependent bulk synaptic vesicle endocytosis--a fast, high capacity membrane retrieval mechanism

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Cell- and stimulus-dependent heterogeneity of synaptic vesicle endocytic recycling mechanisms revealed by studies of dynamin 1-null neurons

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

The dynamin middle domain is critical for tetramerization and higher-order self-assembly

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Syndapin I is the phosphorylation-regulated dynamin I partner in synaptic vesicle endocytosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

High-throughput assays for promiscuous inhibitors.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Small molecule inhibitors of dynamin I GTPase activity: development of dimeric tyrphostins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

An assembly-incompetent mutant establishes a requirement for dynamin self-assembly in clathrin-mediated endocytosis in vivo.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Effect of detergent on "promiscuous" inhibitors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

A model for dynamin self-assembly based on binding between three different protein domains

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Ba2+ does not support synaptic vesicle retrieval in rat cerebrocortical synaptosomes.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Ubiquitously expressed dynamin-II has a higher intrinsic GTPase activity and a greater propensity for self-assembly than neuronal dynamin-I

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Dynamin self-assembly stimulates its GTPase activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Synaptosomes possess an exocytotic pool of glutamate

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Interaction of dynamin with microtubules: its structure and GTPase activity investigated by using highly purified dynamin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Region and diagnosis-specific changes in synaptic proteins in schizophrenia and bipolar I disorder

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

A rapid Percoll gradient procedure for preparation of synaptosomes.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Some selective serotonin reuptake inhibitors inhibit dynamin I guanosine triphosphatase (GTPase).

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

GTP-independent rapid and slow endocytosis at a central synapse

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Myristyl Trimethyl Ammonium Bromide and Octadecyl Trimethyl Ammonium Bromide Are Surface-Active Small Molecule Dynamin Inhibitors that Block Endocytosis Mediated by Dynamin I or Dynamin II

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

A high-throughput screen for aggregation-based inhibition in a large compound library

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Characterization of the urinary albumin degradation pathway in the isolated perfused rat kidney

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Fast gradient HPLC method to determine compounds binding to human serum albumin. Relationships with octanol/water and immobilized artificial membrane lipophilicity.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Fast kinetics of exocytosis revealed by simultaneous measurements of presynaptic capacitance and postsynaptic currents at a central synapse

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138991

Pre- and postsynaptic whole-cell recordings in the medial nucleus of the trapezoid body of the rat

26 November 2018

1 reference

12 December 2020

Identification of small-molecule inhibitors of protein kinase B (PKB/AKT) in an AlphaScreenTM high-throughput screen

1 reference

12 December 2020

Ca2+ Influx Inhibits Dynamin and Arrests Synaptic Vesicle Endocytosis at the Active Zone

1 reference

12 December 2020

Dynasore, an inhibitor of dynamin, increases the probability of transmitter release

1 reference

12 December 2020

Identifiers

DOI

10.1111/TRA.12119

1 reference

1 reference

1 reference

1 reference