(Q30040267)

English

A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria

scientific article (publication date: February 2001)

In more languages

Statements

scholarly article

0 references

A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria (English)

0 references

Plasmodium falciparum

0 references

dihydrofolate synthase/folylpolyglutamate synthase

1 reference

11 September 2018

dihydrofolate synthase/folylpolyglutamate synthase, putative

1 reference

25 September 2018

dihydrofolate synthase/folylpolyglutamate synthase, putative

1 reference

15 December 2018

dihydrofolate synthase/folylpolyglutamate synthase, putative

1 reference

19 December 2018

dihydrofolate synthase/folylpolyglutamate synthase, putative

1 reference

20 December 2018

dihydrofolate synthase/folylpolyglutamate synthase, putative

1 reference

20 December 2018

dihydrofolate synthase/folylpolyglutamate synthase, putative

1 reference

20 December 2018

dihydrofolate synthase/folylpolyglutamate synthase, putative

1 reference

20 December 2018

dihydrofolate synthase/folylpolyglutamate synthase, putative

0 references

author name string

E Salcedo

1

0 references

J F Cortese

2

0 references

C V Plowe

3

0 references

P F Sims

4

0 references

J E Hyde

5

0 references

language of work or name

0 references

publication date

February 2001

0 references

Molecular and Biochemical Parasitology

0 references

112

0 references

2

0 references

239-52

0 references

Synergistic Antimalarial Activity of Pyrimethamine and Sulfadoxine against Plasmodium falciparum In Vitro *

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

P. falciparum dihydrofolate reductase and dihydropteroate synthase mutations: epidemiology and role in clinical resistance to antifolates

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of folylpolyglutamates with enzymes in one-carbon metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulatory role of oxidized and reduced pteroylpolyglutamates

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural homologies with ATP- and folate-binding enzymes in the crystal structure of folylpolyglutamate synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Folylpolyglutamates in Leishmania major

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutagenesis of the Lactobacillus casei folylpolyglutamate synthetase gene at essential residues resembling an ATP binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

De novo and salvage biosynthesis of pteroylpentaglutamates in the human malaria parasite, Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian folylpoly-gamma-glutamate synthetase. 2. Substrate specificity and kinetic properties

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian folylpoly-gamma-glutamate synthetase. 3. Specificity for folate analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation of dihydrofolate and folylpolyglutamate synthetase activities from Neurospora

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Folates and one-carbon metabolism in plants and fungi

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Purification of genomic DNA from human whole blood by isopropanol-fractionation with concentrated Nal and SDS.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288C

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Getting started with yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of seven hypothetical aryl alcohol dehydrogenase genes from Saccharomyces cerevisiae and construction of a multiple knock-out strain

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis in yeast of antimalaria drugs that target the dihydrofolate reductase of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Antifolate resistance due to new and known Plasmodium falciparum dihydrofolate reductase mutations expressed in yeast.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutagenesis of the folC gene encoding folylpolyglutamate synthetase-dihydrofolate synthetase in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of methionine biosynthesis in the enterobacteriaceae

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of the GTP-cyclohydrolase I gene in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Polyglutamylation of folate coenzymes is necessary for methionine biosynthesis and maintenance of intact mitochondrial genome in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of cytoplasmic and mitochondrial folylpolyglutamate synthetase activity in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Yeast as a model system to study drugs effective against apicomplexan proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The dihydrofolate reductase-thymidylate synthetase gene in the drug resistance of malaria parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of three key active site residues in the C-terminal domain of human recombinant folylpoly-gamma-glutamate synthetase by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Initiation of translation in prokaryotes and eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of the sequences flanking the translational start sites of Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of tetanus toxin fragment C in yeast: gene synthesis is required to eliminate fortuitous polyadenylation sites in AT-rich DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic detection of new yeast pre-mRNA 3'-end-processing signals

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Statistical analysis of yeast genomic downstream sequences reveals putative polyadenylation signals

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism-based inhibition of human folylpolyglutamate synthetase: design, synthesis, and biochemical characterization of a phosphapeptide mimic of the tetrahedral intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

5-deazafolate analogues with a rotationally restricted glutamate or ornithine side chain: synthesis and binding interaction with folylpolyglutamate synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression cloning of a human cDNA encoding folylpoly(gamma-glutamate) synthetase and determination of its primary structure

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Purification and characteristics of recombinant human folylpoly-gamma-glutamate synthetase expressed at high levels in insect cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-6851%2800%2900370-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0166-6851(00)00370-4

0 references

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q30040267&oldid=1551454977"