(Q30044020)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

A novel multiple-stage antimalarial agent that inhibits protein synthesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

12 September 2018

0 references

elongation factor 2, putative

1 reference

GeneDB

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis.

19 December 2018

corrigendum / erratum

1 reference

12 July 2019

http://api.crossref.org/works?select=update-to&filter=doi:10.1038/NATURE18280

author

Beatriz Baragaña

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Marcus C S Lee

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Thomas D Otto

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Stephan Meister

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Andrea Ruecker

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Anupam Pradhan

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Fabio Zuccotto

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Patrick Michael Brock

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Thomas S Churcher

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Vicky M. Avery

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Rintis Noviyanti

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Michael Delves

49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Dennis E Kyle

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Richard Price

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Susan A. Charman

54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Elizabeth Winzeler

55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

David W. Gray

58

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Alan Fairlamb

60

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Julian Rayner

61

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

David A. Fidock

64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Ian H. Gilbert

66

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

34

Jennifer Riley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

39

Koen J Dechering

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

38

Robert W Sauerwein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

41

Brice Campo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Maria Belen Jimenez-Diaz

32

María Belén Jiménez-Díaz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

47

Didier Leroy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

48

Peter Siegl

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

46

Paul G Wyatt

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

65

Kevin D Read

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

2

Irene Hallyburton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Neil Richard Norcross

4

Neil R Norcross

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

5

Raffaella Grimaldi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

7

William R Proto

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

8

Andrew M Blagborough

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

12

Leanna M Upton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

13

Tara S Abraham

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

16

Achim Porzelle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

20

Judith M Bolscher

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

21

Andrew Woodland

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

22

Suzanne Norval

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

29

Tom S Churcher

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

31

Sara E Zakutansky

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

33

Laura Maria Sanz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

35

Rajshekhar Basak

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

42

Julie A Frearson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Santiago Ferrer Bazaga

44

Santiago Ferrer-Bazaga

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

57

Lidiya Bebrevska

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

52

Jutta Marfurt

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

10

Grennady Wirjanata

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Iñigo Angulo-Barturen

43

Iñigo Angulo-Barturen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

17

Torsten Luksch

1 reference

17 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

19

Torsten Luksch

1 reference

17 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

Mariana J Almeida

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

María Santos Martínez

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

John Thomas

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Frederick Simeons

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Katarzyna A Sala

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Michael Campbell

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Francisco Javier Gamo

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Ric N Price

53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Simon Campbell

59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Paddy M Brock

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Susan A Charman

56

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Paul A Willis

62

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Julian C Rayner

63

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

language of work or name

English

0 references

publication date

1 June 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

volume

522

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

issue

7556

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

page(s)

315-320

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

17 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Targeting Plasmodium PI(4)K to eliminate malaria

25 May 2017

1 reference

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Using genetic methods to define the targets of compounds with antimalarial activity

25 May 2017

1 reference

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Designing the next generation of medicines for malaria control and eradication

25 May 2017

1 reference

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Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

25 May 2017

1 reference

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P. falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-action

25 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites

25 May 2017

1 reference

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Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid

25 May 2017

1 reference

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

25 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

A research agenda for malaria eradication: drugs

25 May 2017

1 reference

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Interaction of apicoplast-encoded elongation factor (EF) EF-Tu with nuclear-encoded EF-Ts mediates translation in the Plasmodiumfalciparum plastid

25 May 2017

1 reference

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Spiroindolones, a potent compound class for the treatment of malaria

25 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes

25 May 2017

1 reference

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Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase

25 May 2017

1 reference

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The life and death of translation elongation factor 2

25 May 2017

1 reference

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Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase

25 May 2017

1 reference

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A proteomic view of the Plasmodium falciparum life cycle

25 May 2017

1 reference

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High efficiency transfection of Plasmodium berghei facilitates novel selection procedures

25 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Lead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations.

25 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Transmission-blocking interventions eliminate malaria from laboratory populations.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

A framework for assessing the risk of resistance for anti-malarials in development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Malaria morbidity in Papua Indonesia, an area with multidrug resistant Plasmodium vivax and Plasmodium falciparum

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Determinants of in vitro drug susceptibility testing of Plasmodium vivax

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Lessons learnt from assembling screening libraries for drug discovery for neglected diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Species-specific inhibition of fungal protein synthesis by sordarin: identification of a sordarin-specificity region in eukaryotic elongation factor 2.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Translation elongation factor 2 is part of the target for a new family of antifungals

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

A Research Agenda to Underpin Malaria Eradication

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE14451

A high-throughput assay for the identification of malarial transmission-blocking drugs and vaccines

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE14451

Quantitative measurement of Plasmodium-infected erythrocytes in murine models of malaria by flow cytometry using bidimensional assessment of SYTO-16 fluorescence

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700930

Elongation factor 2 as a novel target for selective inhibition of fungal protein synthesis

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26085270

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE14451

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

26085270

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26085270%20AND%20SRC:MED&resulttype=core&format=json