(Q30145664)

English

Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists

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scholarly article

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists (English)

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

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8

object named as

Sujan Shresta

1 reference

Europe PubMed Central

4 July 2018

Annie Elong Ngono

6

object named as

Annie Elong Ngono

1 reference

Europe PubMed Central

4 July 2018

Alexey V Terskikh

12

object named as

Alexey V Terskikh

1 reference

Europe PubMed Central

4 July 2018

author name string

Sergey A Shiryaev

1

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

Chen Farhy

2

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

Antonella Pinto

3

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

Chun-Teng Huang

4

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

Nicole Simonetti

5

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

Antimone Dewing

7

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

Anthony B Pinkerton

9

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

Piotr Cieplak

10

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

Alex Y Strongin

11

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Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

language of work or name

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publication date

29 April 2017

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Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

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12

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Antiviral Research

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

143

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Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

218-229

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Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

on focus list of Wikimedia project

WikiProject Zika Corpus

0 references

Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Structure of the NS2B-NS3 protease from Zika virus after self-cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Zika virus epidemic in Brazil. I. Fatal disease in adults: clinical and laboratorial aspects

1 reference

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14 July 2018

Mechanisms of activation and inhibition of Zika virus NS2B-NS3 protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Nonstructural Proteins Are Preferential Positive Selection Targets in Zika Virus and Related Flaviviruses

1 reference

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14 July 2018

Zika Virus Infects Neural Progenitors in the Adult Mouse Brain and Alters Proliferation

1 reference

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14 July 2018

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

1 reference

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14 July 2018

Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

The Brazilian Zika virus strain causes birth defects in experimental models

1 reference

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14 July 2018

Zika Virus Associated with Microcephaly

1 reference

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14 July 2018

Zika Virus Outbreak, Bahia, Brazil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

The flavivirus NS2B-NS3 protease-helicase as a target for antiviral drug development

1 reference

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14 July 2018

SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis

1 reference

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14 July 2018

Structural and functional parameters of the flaviviral protease: a promising antiviral drug target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Virtual ligand screening of the National Cancer Institute (NCI) compound library leads to the allosteric inhibitory scaffolds of the West Nile Virus NS3 proteinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Structure–activity relationship and improved hydrolytic stability of pyrazole derivatives that are allosteric inhibitors of West Nile Virus NS2B-NS3 proteinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Autocatalytic activation of the furin zymogen requires removal of the emerging enzyme's N-terminus from the active site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Structural evidence for regulation and specificity of flaviviral proteases and evolution of theFlaviviridaefold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Expression and purification of a two-component flaviviral proteinase resistant to autocleavage at the NS2B–NS3 junction region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Yellow fever virus NS2B-NS3 protease: characterization of charged-to-alanine mutant and revertant viruses and analysis of polyprotein-cleavage activities

1 reference

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14 July 2018

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

14 July 2018

Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain

1 reference

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14 July 2018

Furin at the cutting edge: from protein traffic to embryogenesis and disease

1 reference

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14 July 2018

Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro

1 reference

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14 July 2018

Deletion analysis of dengue virus type 4 nonstructural protein NS2B: identification of a domain required for NS2B-NS3 protease activity

1 reference

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14 July 2018

Human ESC-derived neural crest model reveals a key role for SOX2 in sensory neurogenesis

1 reference

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26 November 2018

Fast docking using the CHARMM force field with EADock DSS.

1 reference

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26 November 2018

Impaired generation of mature neurons by neural stem cells from hypomorphic Sox2 mutants.

1 reference

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26 November 2018

SOX2 mutation causes anophthalmia, hearing loss, and brain anomalies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5558795

26 November 2018

Identifiers

10.1016/J.ANTIVIRAL.2017.04.015

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

1 reference

Europe PubMed Central

4 July 2018

http://europepmc.org/abstract/PMC/5558795

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