(Q30157439)

8 June 2017

title

MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis (English)

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MET transcriptional regulator MACC1

8 June 2017

main subject

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positive regulation of transcription by RNA polymerase II

GOA release 2020-03-11

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GOA release 2020-03-11

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Ulrike Stein

1

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8 June 2017

Wolfgang Walther

2

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8 June 2017

Franziska Arlt

3

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8 June 2017

Holger Schwabe

4

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8 June 2017

Janice Smith

5

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8 June 2017

Iduna Fichtner

6

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8 June 2017

Walter Birchmeier

7

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8 June 2017

Peter M Schlag

8

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8 June 2017

language of work or name

English

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publication date

21 December 2008

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8 June 2017

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8 June 2017

volume

15

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8 June 2017

issue

1

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8 June 2017

page(s)

59-67

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New signals from the invasive front

8 June 2017

cites work

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Staging of cancer of the colon and rectum

21 January 2018

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Tumour markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines for clinical use.

21 January 2018

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A genetic model for colorectal tumorigenesis

21 January 2018

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21 January 2018

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Cancer genes and the pathways they control

21 January 2018

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Colorectal cancer: genetics of development and metastasis

21 January 2018

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Met, metastasis, motility and more

21 January 2018

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The Met pathway: master switch and drug target in cancer progression

21 January 2018

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c-Met and hepatocyte growth factor: potential as novel targets in cancer therapy

21 January 2018

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Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

21 January 2018

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c-Met is essential for wound healing in the skin

21 January 2018

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Invasive growth: a MET-driven genetic programme for cancer and stem cells

21 January 2018

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Experimental and clinicopathologic studies on the function of the HGF receptor in human colon cancer metastasis

21 January 2018

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Molecular co-expression of the c-Met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome.

21 January 2018

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Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction

21 January 2018

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Complete sequencing and characterization of 21,243 full-length human cDNAs

21 January 2018

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Cloning, chromosomal localization, and characterization of cDNA from a novel gene, SH3BP4, expressed by human corneal fibroblasts

21 January 2018

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The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells

21 January 2018

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Sensitive PCR method for the detection and real-time quantification of human cells in xenotransplantation systems

21 January 2018

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Assembly of Cell Regulatory Systems Through Protein Interaction Domains

21 January 2018

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Topology of transmembrane segments 1-4 in the human chloride/bicarbonate anion exchanger 1 (AE1) by scanning N-glycosylation mutagenesis

21 January 2018

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Protein-tyrosine phosphatases and cancer

21 January 2018

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The human hepatocyte growth factor receptor gene: complete structural organization and promoter characterization

21 January 2018

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Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

21 January 2018

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Interplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesis

21 January 2018

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Negative feedback regulation of Met-dependent invasive growth by Notch

21 January 2018

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Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly

21 January 2018

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Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.

21 January 2018

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Knockdown of c-Met by adenovirus-delivered small interfering RNA inhibits hepatocellular carcinoma growth in vitro and in vivo

21 January 2018

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Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation

21 January 2018

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Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice

21 January 2018

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Hepatocyte growth factor promotes hepatocarcinogenesis through c-Met autocrine activation and enhanced angiogenesis in transgenic mice treated with diethylnitrosamine

21 January 2018

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In vivo direct molecular imaging of early tumorigenesis and malignant progression induced by transgenic expression of GFP-Met

21 January 2018

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Targeting the c-Met signaling pathway in cancer

21 January 2018

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A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth

21 January 2018

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An epithelial scatter factor released by embryo fibroblasts.

21 January 2018

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12 December 2020

The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer

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12 December 2020

Role of HGF/SF and c-Met in morphogenesis and metastasis of epithelial cells

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12 December 2020

Classification of human colorectal adenocarcinoma cell lines

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12 December 2020

Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer

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12 December 2020

Expression of c-met proto-oncogene in primary colorectal cancer and liver metastases

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12 December 2020

c-MET expression level in primary colon cancer: a predictor of tumor invasion and lymph node metastases.

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12 December 2020

Clinical, biological, and molecular aspects of metastasis in colorectal cancer.

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12 December 2020

Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity

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12 December 2020

Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction

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12 December 2020

Wnt signaling regulates expression of the receptor tyrosine kinase met in colorectal cancer

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12 December 2020

UKCCCR guidelines for the welfare of animals in experimental neoplasia

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12 December 2020

Sp1 regulates expression of MET, and ribozyme-induced down-regulation of MET in fibrosarcoma-derived human cells reduces or eliminates their tumorigenicity.

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12 December 2020

Expression and genomic profiling of colorectal cancer

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12 December 2020

Identifiers

DOI

10.1038/NM.1889

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8 June 2017

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