(Q30157440)

18 August 2017

Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer (English)

1 reference

18 August 2017

8

Charles Glabe

1 reference

18 August 2017

1

Rakez Kayed

1 reference

18 August 2017

2

Anna Pensalfini

1 reference

18 August 2017

Larry Margol

3

1 reference

18 August 2017

Yuri Sokolov

4

1 reference

18 August 2017

Floyd Sarsoza

5

1 reference

18 August 2017

Elizabeth Head

6

1 reference

18 August 2017

James Hall

7

1 reference

18 August 2017

language of work or name

English

0 references

publication date

18 December 2008

1 reference

18 August 2017

8

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

18 August 2017

284

1 reference

18 August 2017

4230-4237

1 reference

18 August 2017

7

1 reference

Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

A common fold mediates vertebrate defense and bacterial attack

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Atomic structures of amyloid cross-beta spines reveal varied steric zippers

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Soluble amyloid oligomers increase bilayer conductance by altering dielectric structure

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Conformation-dependent anti-amyloid oligomer antibodies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Protein aggregation and its consequences for human disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Expression of normal sequence pathogenic proteins for neurodegenerative disease contributes to disease risk: 'permissive templating' as a general mechanism underlying neurodegeneration

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

3 June 2018

Amyloid peptide channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Mixtures of wild-type and a pathogenic (E22G) form of Abeta40 in vitro accumulate protofibrils, including amyloid pores.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Rationalization of the effects of mutations on peptide and protein aggregation rates.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Beta-barrel membrane protein folding and structure viewed through the lens of alpha-hemolysin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Conformational Abs recognizing a generic amyloid fibril epitope

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Structural and functional imaging with carbon nanotube AFM probes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Antibody-mediated resolution of light chain-associated amyloid deposits.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

On the mechanism of membrane damage by Staphylococcus aureus alpha-toxin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808591200

Prefibrillar amyloid aggregates could be generic toxins in higher organisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808591200

Soluble amyloid Abeta-(1-40) exists as a stable dimer at low concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808591200

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808591200

Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808591200

Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808591200

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808591200

Pore-forming proteins share structural and functional homology with amyloid oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808591200

Neurodegenerative disease: amyloid pores from pathogenic mutations.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Surfactant properties of Alzheimer's A beta peptides and the mechanism of amyloid aggregation.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2640961

Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19098006

12 December 2020

inferred from PubMed ID database lookup

Molecular crowding accelerates fibrillization of alpha-synuclein: could an increase in the cytoplasmic protein concentration induce Parkinson's disease?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19098006

12 December 2020

inferred from PubMed ID database lookup

Observation of metastable Abeta amyloid protofibrils by atomic force microscopy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19098006

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M808591200

1 reference

18 August 2017

1 reference

18 August 2017

1 reference