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Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activities
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
title
Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activities
(English)
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
main subject
phosphorylation
1 reference
based on heuristic
inferred from title
author
Ivan Đikić
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Oliver Bogler
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Mirko H H Schmidt
series ordinal
1
object named as
Mirko Schmidt
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
language of work or name
English
0 references
publication date
22 November 2004
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
number of pages
12
1 reference
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inferred from page(s)
published in
Journal of Biological Chemistry
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
volume
280
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
page(s)
3414-3425
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
cites work
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PubMed Central
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Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex.
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PubMed Central
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3 June 2018
ALIX-ing phospholipids with endosome biogenesis
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PubMed Central
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3 June 2018
Role of LBPA and Alix in multivesicular liposome formation and endosome organization
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3 June 2018
AIP1/ALIX Is a Binding Partner for HIV-1 p6 and EIAV p9 Functioning in Virus Budding
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Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors.
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3 June 2018
The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting
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PubMed Central
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3 June 2018
SETA/CIN85/Ruk and its binding partner AIP1 associate with diverse cytoskeletal elements, including FAKs, and modulate cell adhesion
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Use of an immobilized monoclonal antibody to examine integrin α5β1 signaling independent of cell spreading
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Negative receptor signalling
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Hp95 promotes anoikis and inhibits tumorigenicity of HeLa cells
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CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases
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Cell attachment to the extracellular matrix induces proteasomal degradation of p21(CIP1) via Cdc42/Rac1 signaling
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3 June 2018
Alix (ALG-2-interacting protein X), a protein involved in apoptosis, binds to endophilins and induces cytoplasmic vacuolization
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PubMed Central
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3 June 2018
Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
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3 June 2018
The PROSITE database, its status in 2002
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3 June 2018
Overexpression of Hp95 induces G1 phase arrest in confluent HeLa cells
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3 June 2018
The hunting of the Src
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3 June 2018
Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180480
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3 June 2018
SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins
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PubMed Central
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3 June 2018
Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180480
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3 June 2018
The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes
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3 June 2018
Src family tyrosine kinases and growth factor signaling
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3 June 2018
Crystal structures of c-Src reveal features of its autoinhibitory mechanism
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Src family kinases are required for integrin but not PDGFR signal transduction.
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Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptosis-linked-gene 2 (ALG-2) protein
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3 June 2018
Identification and cloning of xp95, a putative signal transduction protein in Xenopus oocytes
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3 June 2018
Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction
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3 June 2018
Cellular functions regulated by Src family kinases
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3 June 2018
Three-dimensional structure of the tyrosine kinase c-Src
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180480
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3 June 2018
Mutation of a Src phosphorylation site in the PDGF beta-receptor leads to increased PDGF-stimulated chemotaxis but decreased mitogenesis
1 reference
stated in
PubMed Central
reference URL
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3 June 2018
Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands
1 reference
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PubMed Central
reference URL
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3 June 2018
Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3
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3 June 2018
Receptor tyrosine kinases and their targets
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3 June 2018
Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries.
1 reference
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3 June 2018
c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism
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3 June 2018
Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.
1 reference
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180480
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3 June 2018
Structural basis for the binding of proline-rich peptides to SH3 domains
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180480
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3 June 2018
Phage display selection of ligand residues important for Src homology 3 domain binding specificity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180480
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3 June 2018
Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
1 reference
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PubMed Central
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3 June 2018
Identifiers
DOI
10.1074/JBC.M409839200
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
PMCID
1180480
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
PubMed ID
15557335
1 reference
stated in
Europe PubMed Central
PMCID
1180480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
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