(Q30244811)

12 June 2017

3 references

13 July 2022

22 October 2022

Coronavirus Spike Protein and Tropism Changes (English)

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12 June 2017

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R J G Hulswit

1

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12 June 2017

C A M de Haan

series ordinal

2

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12 June 2017

B-J Bosch

series ordinal

3

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12 June 2017

publication date

13 September 2016

3 references

Advances in Virus Research

12 June 2017

13 July 2022

22 October 2022

3 references

12 June 2017

13 July 2022

22 October 2022

96

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12 June 2017

page(s)

29-57

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The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses.

12 June 2017

cites work

1 reference

12 December 2020

Structure of the Fusion Core and Inhibition of Fusion by a Heptad Repeat Peptide Derived from the S Protein of Middle East Respiratory Syndrome Coronavirus

1 reference

12 December 2020

Porcine epidemic diarrhea: a review of current epidemiology and available vaccines

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study.

1 reference

12 December 2020

Manipulation of the coronavirus genome using targeted RNA recombination with interspecies chimeric coronaviruses

1 reference

12 December 2020

Persistent infection promotes cross-species transmissibility of mouse hepatitis virus

1 reference

12 December 2020

Identification of a receptor-binding domain of the spike glycoprotein of human coronavirus HCoV-229E.

1 reference

12 December 2020

Conformational changes in the spike glycoprotein of murine coronavirus are induced at 37 degrees C either by soluble murine CEACAM1 receptors or by pH 8.

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides.

1 reference

12 December 2020

Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor

1 reference

12 December 2020

Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4.

1 reference

12 December 2020

Aminopeptidase N is a major receptor for the entero-pathogenic coronavirus TGEV

1 reference

12 December 2020

Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor

1 reference

12 December 2020

Feline infectious peritonitis virus with a large deletion in the 5'-terminal region of the spike gene retains its virulence for cats

1 reference

12 December 2020

Point mutations in the S protein connect the sialic acid binding activity with the enteropathogenicity of transmissible gastroenteritis coronavirus

1 reference

12 December 2020

Heptad repeat sequences are located adjacent to hydrophobic regions in several types of virus fusion glycoproteins

1 reference

12 December 2020

Attachment of mouse hepatitis virus to O-acetylated sialic acid is mediated by hemagglutinin-esterase and not by the spike protein

1 reference

12 December 2020

Amino acid substitutions within the heptad repeat domain 1 of murine coronavirus spike protein restrict viral antigen spread in the central nervous system

1 reference

12 December 2020

Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China

1 reference

12 December 2020

Clathrin-dependent entry of severe acute respiratory syndrome coronavirus into target cells expressing ACE2 with the cytoplasmic tail deleted

1 reference

12 December 2020

Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses

1 reference

12 December 2020

Porcine Epidemic Diarrhea Virus and Discovery of a Recombinant Swine Enteric Coronavirus, Italy.

1 reference

12 December 2020

Cooperative involvement of the S1 and S2 subunits of the murine coronavirus spike protein in receptor binding and extended host range.

1 reference

12 December 2020

Cell receptor-independent infection by a neurotropic murine coronavirus

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12 December 2020

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.

1 reference

12 December 2020

Feline aminopeptidase N serves as a receptor for feline, canine, porcine, and human coronaviruses in serogroup I

1 reference

12 December 2020

Coronavirus spike proteins in viral entry and pathogenesis

1 reference

12 December 2020

Role of Endocytosis and Low pH in Murine Hepatitis Virus Strain A59 Cell Entry

1 reference

12 December 2020

Multiple receptor-dependent steps determine the species specificity of HCV-229E infection.

1 reference

12 December 2020

Bat origins of MERS-CoV supported by bat coronavirus HKU4 usage of human receptor CD26

1 reference

12 December 2020

The first complete genome sequences of clinical isolates of human coronavirus 229E

1 reference

12 December 2020

Evidence supporting a zoonotic origin of human coronavirus strain NL63

1 reference

12 December 2020

Amino acid substitutions in the S2 subunit of mouse hepatitis virus variant V51 encode determinants of host range expansion

1 reference

12 December 2020

Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus

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12 December 2020

Order and disorder control the functional rearrangement of influenza hemagglutinin

1 reference

12 December 2020

Identification of the Fusion Peptide-Containing Region in Betacoronavirus Spike Glycoproteins

1 reference

12 December 2020

Structure of a proteolytically resistant core from the severe acute respiratory syndrome coronavirus S2 fusion protein

1 reference

12 December 2020

Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor

1 reference

12 December 2020

Antibodies to SARS coronavirus in civets

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12 December 2020

Receptor recognition mechanisms of coronaviruses: a decade of structural studies

1 reference

12 December 2020

New Chimeric Porcine Coronavirus in Swine Feces, Germany, 2012

1 reference

12 December 2020

Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

1 reference

12 December 2020

Central ions and lateral asparagine/glutamine zippers stabilize the post-fusion hairpin conformation of the SARS coronavirus spike glycoprotein

1 reference

12 December 2020

Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis

1 reference

12 December 2020

Evidence for a common evolutionary origin of coronavirus spike protein receptor-binding subunits

1 reference

12 December 2020

S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected patients

1 reference

12 December 2020

Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus

1 reference

12 December 2020

Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2.

1 reference

12 December 2020

Identification of residues critical for the human coronavirus 229E receptor function of human aminopeptidase N.

1 reference

12 December 2020

Sequence analysis of the spike protein gene of murine coronavirus variants: study of genetic sites affecting neuropathogenicity.

1 reference

12 December 2020

Pre-fusion structure of a human coronavirus spike protein.

1 reference

12 December 2020

Variations in disparate regions of the murine coronavirus spike protein impact the initiation of membrane fusion

1 reference

12 December 2020

Complete genome sequence of bat coronavirus HKU2 from Chinese horseshoe bats revealed a much smaller spike gene with a different evolutionary lineage from the rest of the genome

1 reference

12 December 2020

Identification of spike protein residues of murine coronavirus responsible for receptor-binding activity by use of soluble receptor-resistant mutants.

1 reference

12 December 2020

Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice

1 reference

12 December 2020

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

1 reference

12 December 2020

An update on feline infectious peritonitis: virology and immunopathogenesis

1 reference

12 December 2020

Mutational analysis of aminopeptidase N, a receptor for several group 1 coronaviruses, identifies key determinants of viral host range

1 reference

12 December 2020

Basolateral internalization of GPI-anchored proteins occurs via a clathrin-independent flotillin-dependent pathway in polarized hepatic cells

1 reference

12 December 2020

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

1 reference

12 December 2020

Dissemination of MHV4 (strain JHM) infection does not require specific coronavirus receptors

1 reference

12 December 2020

Feline aminopeptidase N is a receptor for all group I coronaviruses

1 reference

12 December 2020

SARS-CoV and emergent coronaviruses: viral determinants of interspecies transmission

1 reference

12 December 2020

Identification and characterization of a novel alpaca respiratory coronavirus most closely related to the human coronavirus 229E.

1 reference

12 December 2020

The S protein of bovine coronavirus is a hemagglutinin recognizing 9-O-acetylated sialic acid as a receptor determinant

1 reference

12 December 2020

Binding of transmissible gastroenteritis coronavirus to brush border membrane sialoglycoproteins

1 reference

12 December 2020

Emergence of pathogenic coronaviruses in cats by homologous recombination between feline and canine coronaviruses

1 reference

12 December 2020

Transmissible gastroenteritis coronavirus, but not the related porcine respiratory coronavirus, has a sialic acid (N-glycolylneuraminic acid) binding activity.

1 reference

12 December 2020

Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequences

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus quasispecies that include homologues of human isolates revealed through whole-genome analysis and virus cultured from dromedary camels in Saudi Arabia

1 reference

12 December 2020

Differential Expression of the Middle East Respiratory Syndrome Coronavirus Receptor in the Upper Respiratory Tracts of Humans and Dromedary Camels

1 reference

12 December 2020

Human and bovine coronaviruses recognize sialic acid-containing receptors similar to those of influenza C viruses

1 reference

12 December 2020

Membrane ectopeptidases targeted by human coronaviruses

1 reference

12 December 2020

Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor

1 reference

12 December 2020

The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies

1 reference

12 December 2020

Evolutionary history of the closely related group 2 coronaviruses: porcine hemagglutinating encephalomyelitis virus, bovine coronavirus, and human coronavirus OC43

1 reference

12 December 2020

Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

1 reference

12 December 2020

Infection with MERS-CoV causes lethal pneumonia in the common marmoset

1 reference

12 December 2020

Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core

1 reference

12 December 2020

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

1 reference

12 December 2020

SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway

1 reference

12 December 2020

Structural and functional analysis of the surface protein of human coronavirus OC43.

1 reference

12 December 2020

Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus

1 reference

12 December 2020

Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus infection in dromedary camels in Saudi Arabia

1 reference

12 December 2020

Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines

1 reference

12 December 2020

Proteolytic activation of the spike protein at a novel RRRR/S motif is implicated in furin-dependent entry, syncytium formation, and infectivity of coronavirus infectious bronchitis virus in cultured cells

1 reference

12 December 2020

Receptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection

1 reference

12 December 2020

Evidence for an Ancestral Association of Human Coronavirus 229E with Bats

1 reference

12 December 2020

Murine coronavirus evolution in vivo: functional compensation of a detrimental amino acid substitution in the receptor binding domain of the spike glycoprotein.

1 reference

12 December 2020

A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice

1 reference

12 December 2020

Site-specific alteration of murine hepatitis virus type 4 peplomer glycoprotein E2 results in reduced neurovirulence

1 reference

12 December 2020

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

1 reference

12 December 2020

Crystal Structure of Bovine Coronavirus Spike Protein Lectin Domain

1 reference

12 December 2020

Replicative Capacity of MERS Coronavirus in Livestock Cell Lines

1 reference

12 December 2020

Structure of SARS coronavirus spike receptor-binding domain complexed with receptor

1 reference

12 December 2020

MHV neuropathogenesis: the study of chimeric S genes and mutations in the hypervariable region

1 reference

12 December 2020

Structural basis for paramyxovirus-mediated membrane fusion

1 reference

12 December 2020

Bat origin of human coronaviruses.

1 reference

12 December 2020

Retargeting of coronavirus by substitution of the spike glycoprotein ectodomain: crossing the host cell species barrier

1 reference

12 December 2020

Animal origins of the severe acute respiratory syndrome coronavirus: insight from ACE2-S-protein interactions

1 reference

12 December 2020

Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy

1 reference

12 December 2020

Porcine epidemic diarrhea virus: An emerging and re-emerging epizootic swine virus

1 reference

12 December 2020

Acquisition of cell-cell fusion activity by amino acid substitutions in spike protein determines the infectivity of a coronavirus in cultured cells

1 reference

12 December 2020

Protein unfolding is essential for cleavage within the α-helix of a model protein substrate by the serine protease, thrombin.

1 reference

12 December 2020

Murine coronavirus with an extended host range uses heparan sulfate as an entry receptor

1 reference

12 December 2020

Evidence for camel-to-human transmission of MERS coronavirus

1 reference

12 December 2020

The molecular genetics of feline coronaviruses: comparative sequence analysis of the ORF7a/7b transcription unit of different biotypes

1 reference

12 December 2020

Mapping of the receptor-binding domain and amino acids critical for attachment in the spike protein of avian coronavirus infectious bronchitis virus

1 reference

12 December 2020

Difference in receptor usage between severe acute respiratory syndrome (SARS) coronavirus and SARS-like coronavirus of bat origin

1 reference

12 December 2020

Soluble receptor potentiates receptor-independent infection by murine coronavirus

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12 December 2020

Mutation in spike protein cleavage site and pathogenesis of feline coronavirus

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12 December 2020

Interspecies transmission and emergence of novel viruses: lessons from bats and birds

1 reference

12 December 2020

Human coronavirus 229E binds to CD13 in rafts and enters the cell through caveolae

1 reference

12 December 2020

Spike protein fusion peptide and feline coronavirus virulence.

1 reference

12 December 2020

Proteolytic cleavage of the E2 glycoprotein of murine coronavirus: host-dependent differences in proteolytic cleavage and cell fusion.

1 reference

12 December 2020

Acquisition of macrophage tropism during the pathogenesis of feline infectious peritonitis is determined by mutations in the feline coronavirus spike protein

1 reference

12 December 2020

Identification of two critical amino acid residues of the severe acute respiratory syndrome coronavirus spike protein for its variation in zoonotic tropism transition via a double substitution strategy.

1 reference

12 December 2020

Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human

1 reference

12 December 2020

The murine coronavirus mouse hepatitis virus strain A59 from persistently infected murine cells exhibits an extended host range

1 reference

12 December 2020

Role of sialic acids in feline enteric coronavirus infections

1 reference

12 December 2020

Genotyping coronaviruses associated with feline infectious peritonitis.

1 reference

12 December 2020

Experimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte cultures

1 reference

12 December 2020

The paradox of feline coronavirus pathogenesis: a review

1 reference

12 December 2020

The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex

1 reference

12 December 2020

A Single Point Mutation Creating a Furin Cleavage Site in the Spike Protein Renders Porcine Epidemic Diarrhea Coronavirus Trypsin Independent for Cell Entry and Fusion.

1 reference

12 December 2020

Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies

1 reference

12 December 2020

Mutations of 3c and spike protein genes correlate with the occurrence of feline infectious peritonitis

1 reference

12 December 2020

Two-step conformational changes in a coronavirus envelope glycoprotein mediated by receptor binding and proteolysis

1 reference

12 December 2020

Switching species tropism: an effective way to manipulate the feline coronavirus genome

1 reference

12 December 2020

10.1016/BS.AIVIR.2016.08.004

Identifiers

DOI

1 reference

12 June 2017

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