(Q73811646)

English

Amino acid substitutions within the heptad repeat domain 1 of murine coronavirus spike protein restrict viral antigen spread in the central nervous system

scientific article published on 01 August 2003

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scholarly article

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6 November 2019

Amino acid substitutions within the heptad repeat domain 1 of murine coronavirus spike protein restrict viral antigen spread in the central nervous system (English)

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6 November 2019

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Susan R Weiss

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6 November 2019

author name string

Jean C Tsai

1

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6 November 2019

Linda de Groot

2

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6 November 2019

Josefina D Pinon

3

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6 November 2019

Kathryn T Iacono

4

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6 November 2019

Joanna J Phillips

5

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6 November 2019

Su-hun Seo

6

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6 November 2019

Ehud Lavi

7

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6 November 2019

publication date

1 August 2003

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6 November 2019

312

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6 November 2019

2

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6 November 2019

369-380

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6 November 2019

Two neurotropic viruses, herpes simplex virus type 1 and mouse hepatitis virus, spread along different neural pathways from the main olfactory bulb.

1 reference

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Influenza hemagglutinin is spring-loaded by a metastable native conformation

1 reference

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7 January 2021

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Evidence for a coiled-coil structure in the spike proteins of coronaviruses

1 reference

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7 January 2021

based on heuristic

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Coronavirus spike proteins in viral entry and pathogenesis

1 reference

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7 January 2021

based on heuristic

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Variations in disparate regions of the murine coronavirus spike protein impact the initiation of membrane fusion

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Retargeting of coronavirus by substitution of the spike glycoprotein ectodomain: crossing the host cell species barrier

1 reference

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7 January 2021

based on heuristic

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Experimental demyelination produced by the A59 strain of mouse hepatitis virus

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered pathogenesis of a mutant of the murine coronavirus MHV-A59 is associated with a Q159L amino acid substitution in the spike protein

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Quaternary structure of coronavirus spikes in complex with carcinoembryonic antigen-related cell adhesion molecule cellular receptors

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Roles in cell-to-cell fusion of two conserved hydrophobic regions in the murine coronavirus spike protein

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Receptor-induced conformational changes of murine coronavirus spike protein

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Communication between S1N330 and a region in S2 of murine coronavirus spike protein is important for virus entry into cells expressing CEACAM1b receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Entry of mouse hepatitis virus into cells by endosomal and nonendosomal pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Murine coronavirus spike protein determines the ability of the virus to replicate in the liver and cause hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of expression of gene 4 of mouse hepatitis virus strain JHM does not affect virulence in the murine CNS.

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence analysis reveals extensive polymorphism and evidence of deletions within the E2 glycoprotein gene of several strains of murine hepatitis virus

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Murine coronavirus spike glycoprotein mediates degree of viral spread, inflammation, and virus-induced immunopathology in the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple regions of the murine coronavirus spike glycoprotein influence neurovirulence

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

LearnCoil-VMF: computational evidence for coiled-coil-like motifs in many viral membrane-fusion proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Soluble receptor potentiates receptor-independent infection by murine coronavirus

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro properties and pathogenesis of A59/MHV4 chimeric mouse hepatitis viruses

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The N-terminal domain of the murine coronavirus spike glycoprotein determines the CEACAM1 receptor specificity of the virus strain

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence analysis of the spike protein gene of murine coronavirus variants: study of genetic sites affecting neuropathogenicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Membrane fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Conformational changes in the spike glycoprotein of murine coronavirus are induced at 37 degrees C either by soluble murine CEACAM1 receptors or by pH 8.

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of spike protein residues of murine coronavirus responsible for receptor-binding activity by use of soluble receptor-resistant mutants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis of chimeric MHV4/MHV-A59 recombinant viruses: the murine coronavirus spike protein is a major determinant of neurovirulence

1 reference

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An essential secondary structure in the 3' untranslated region of the mouse hepatitis virus genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine induction during T-cell-mediated clearance of mouse hepatitis virus from neurons in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of neutralizing epitopes and the receptor-binding site within the amino-terminal 330 amino acids of the murine coronavirus spike protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid substitutions within the leucine zipper domain of the murine coronavirus spike protein cause defects in oligomerization and the ability to induce cell-to-cell fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV

1 reference

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-specific alteration of murine hepatitis virus type 4 peplomer glycoprotein E2 results in reduced neurovirulence

1 reference

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of the pH dependence of coronavirus-induced cell fusion: effect of mutations in the spike glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of coronavirus MHV pathogenesis are localized to 3' portions of the genome as determined by ribonucleic acid-ribonucleic acid recombination.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted recombination within the spike gene of murine coronavirus mouse hepatitis virus-A59: Q159 is a determinant of hepatotropism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage of the E2 glycoprotein of murine coronavirus: host-dependent differences in proteolytic cleavage and cell fusion.

2 references

https://pubmed.ncbi.nlm.nih.gov/12919742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900248-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0042-6822(03)00248-4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12919742%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

Europe PubMed Central

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6 November 2019

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