(Q30252965)

19 October 2017

Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival (English)

1 reference

19 October 2017

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Nigel Turner

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

David James

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Kyle L. Hoehn

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

9

Gregory J Cooney

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Marin E Nelson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Sujoy Lahiri

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Jenny D Y Chow

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Stefan R Hargett

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

David S Breen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Ellen M Olzomer

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Lindsay E Wu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Jill K Slack-Davis

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Carolin Lackner

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Stephen H Caldwell

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

0 references

publication date

14 March 2017

1 reference

19 October 2017

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

14689

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

1 June 2020

copyright license

start time

14 March 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

1 reference

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Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer.

3 June 2018

1 reference

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Dietary sugar intake increases liver tumor incidence in female mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.

3 June 2018

1 reference

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Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Women at extreme risk for obesity-related carcinogenesis: Baseline endometrial pathology and impact of bariatric surgery on weight, metabolic profiles and quality of life

3 June 2018

1 reference

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Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Metabolic vulnerabilities in endometrial cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

SREBP-1 has a prognostic role and contributes to invasion and metastasis in human hepatocellular carcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Lipogenesis and lipolysis: the pathways exploited by the cancer cells to acquire fatty acids

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

FGF3/FGF4 amplification and multiple lung metastases in responders to sorafenib in hepatocellular carcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Hepatocellular Carcinoma: Consensus Recommendations of the National Cancer Institute Clinical Trials Planning Meeting

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

A meta-analysis of survival rates of untreated patients in randomized clinical trials of hepatocellular carcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Experimental mouse models for hepatocellular carcinoma research

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Sorafenib in advanced hepatocellular carcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice

3 June 2018

1 reference

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Hepatocellular carcinoma pathogenesis: from genes to environment

3 June 2018

1 reference

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Increased lipogenesis in cancer cells: new players, novel targets.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

ONCOMINE: a cancer microarray database and integrated data-mining platform

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

A simple method for the isolation and purification of total lipides from animal tissues

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Relevance of hepatic preneoplasia for human hepatocarcinogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Gene expression patterns in human liver cancers

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

N-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5424065

Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma

3 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14689

Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14689

Application of comparative functional genomics to identify best-fit mouse models to study human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14689

Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14689

[De novo lipogenesis: role in hepatocellular carcinoma].

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14689

De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14689

The lipogenesis pathway as a cancer target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14689

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS14689

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 June 2020

ADS bibcode

2017NatCo...814689N

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28290443%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

28290443

1 reference