(Q30268355)

13 June 2017

title

Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB. (English)

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13 June 2017

author

Christoph von Ballmoos

2

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François Verrey

5

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Lorenz Brandstätter

4

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Kay Diederichs

6

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author name string

Markus A Seeger

1

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13 June 2017

Thomas Eicher

3

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13 June 2017

Klaas M Pos

7

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13 June 2017

publication date

27 January 2008

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Nature Structural & Molecular Biology

13 June 2017

published in

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13 June 2017

volume

15

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13 June 2017

issue

2

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13 June 2017

page(s)

199-205

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Efflux-mediated multiresistance in Gram-negative bacteria

13 June 2017

cites work

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Multidrug resistance mechanisms: drug efflux across two membranes

31 March 2020

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Multidrug-exporting secondary transporters

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Three's company: component structures bring a closer view of tripartite drug efflux pumps.

31 March 2020

1 reference

Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export

31 March 2020

1 reference

Crystal structure of bacterial multidrug efflux transporter AcrB

31 March 2020

1 reference

Crystallographic analysis of AcrB.

31 March 2020

1 reference

Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.

31 March 2020

1 reference

Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.

31 March 2020

1 reference

Conformational flexibility in the multidrug efflux system protein AcrA.

31 March 2020

1 reference

Transition to the open state of the TolC periplasmic tunnel entrance

31 March 2020

1 reference

AcrA, AcrB, and TolC of Escherichia coli Form a Stable Intermembrane Multidrug Efflux Complex

31 March 2020

1 reference

Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system.

31 March 2020

1 reference

A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps

31 March 2020

1 reference

Chimeric analysis of the multicomponent multidrug efflux transporters from gram-negative bacteria.

31 March 2020

1 reference

An elegant means of self-protection in gram-negative bacteria by recognizing and extruding xenobiotics from the periplasmic space

31 March 2020

1 reference

Purification, crystallization and preliminary diffraction studies of AcrB, an inner-membrane multi-drug efflux protein

31 March 2020

1 reference

Structural Basis of Multiple Drug-Binding Capacity of the AcrB Multidrug Efflux Pump

31 March 2020

1 reference

Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria

31 March 2020

1 reference

Multidrug efflux pumps of gram-negative bacteria

31 March 2020

1 reference

Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy

31 March 2020

1 reference

Excluded volume approximation to protein-solvent interaction. The solvent contact model

31 March 2020

1 reference

Disulfide recognition in an optimized threading potential.

31 March 2020

1 reference

Extramembrane central pore of multidrug exporter AcrB in Escherichia coli plays an important role in drug transport

31 March 2020

1 reference

Quantitative evaluation of Escherichia coli host strains for tolerance to cytosine methylation in plasmid and phage recombinants

31 March 2020

1 reference

Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels

31 March 2020

1 reference

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

31 March 2020

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Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

31 March 2020

1 reference

Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose

31 March 2020

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Mass spectrometric analysis of cyanogen bromide fragments of integral membrane proteins at the picomole level: application to rhodopsin

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.1379

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13 June 2017

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