(Q30273576)

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An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly.

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8 March 2020

An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly (English)

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8 March 2020

Maximilian Pfau

2

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8 March 2020

Matthias P. Mayer

5

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8 March 2020

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Daniel Parisotto

1

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8 March 2020

Andrea Scheutzow

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8 March 2020

Klemens Wild

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8 March 2020

Jörg Malsam

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8 March 2020

Irmgard Sinning

7

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8 March 2020

Thomas H Söllner

8

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8 March 2020

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14 February 2014

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8 March 2020

Journal of Biological Chemistry

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8 March 2020

289

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8 March 2020

14

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8 March 2020

9639-9650

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8 March 2020

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11 June 2022

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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3 June 2018

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1 reference

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Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release

1 reference

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3 June 2018

Munc18-1 mutations that strongly impair SNARE-complex binding support normal synaptic transmission.

1 reference

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3 June 2018

Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs

1 reference

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3 June 2018

Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion

1 reference

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3 June 2018

Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex

1 reference

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3 June 2018

Complexin cross-links prefusion SNAREs into a zigzag array

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975013

3 June 2018

Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975013

3 June 2018

Resolving the function of distinct Munc18-1/SNARE protein interaction modes in a reconstituted membrane fusion assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975013

3 June 2018

In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975013

3 June 2018

Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex

1 reference

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3 June 2018

Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation

1 reference

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3 June 2018

SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion.

1 reference

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3 June 2018

Dynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1

1 reference

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3 June 2018

Features and development of Coot

1 reference

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3 June 2018

Binding of Munc18-1 to synaptobrevin and to the SNARE four-helix bundle

1 reference

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3 June 2018

Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation

1 reference

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3 June 2018

Rescue of Munc18-1 and -2 double knockdown reveals the essential functions of interaction between Munc18 and closed syntaxin in PC12 cells

1 reference

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3 June 2018

Munc18/Syntaxin interaction kinetics control secretory vesicle dynamics

1 reference

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3 June 2018

Helical extension of the neuronal SNARE complex into the membrane

1 reference

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3 June 2018

Abrogating Munc18-1-SNARE complex interaction has limited impact on exocytosis in PC12 cells

1 reference

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Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming

1 reference

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Complexin controls the force transfer from SNARE complexes to membranes in fusion

1 reference

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Membrane fusion: grappling with SNARE and SM proteins

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1 reference

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Membrane fusion: SNAREs and regulation

1 reference

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3 June 2018

Conformational switch of syntaxin-1 controls synaptic vesicle fusion

1 reference

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3 June 2018

UNC-18 promotes both the anterograde trafficking and synaptic function of syntaxin

1 reference

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Complexin and Ca2+ stimulate SNARE-mediated membrane fusion

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3 June 2018

NMR analysis of the closed conformation of syntaxin-1.

1 reference

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Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide

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Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex

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SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes

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3 June 2018

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1 reference

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How synaptotagmin promotes membrane fusion.

1 reference

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3 June 2018

Munc18-1 binds directly to the neuronal SNARE complex

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Selective activation of cognate SNAREpins by Sec1/Munc18 proteins

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1 reference

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Munc18-1 promotes large dense-core vesicle docking

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Complexins regulate a late step in Ca2+-dependent neurotransmitter release

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Cascaded multiple classifiers for secondary structure prediction

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Protein secondary structure prediction based on position-specific scoring matrices

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3 June 2018

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3 June 2018

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3 June 2018

SNAREpins: minimal machinery for membrane fusion

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SNAP receptors implicated in vesicle targeting and fusion

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Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin

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Use of resonance energy transfer to monitor membrane fusion

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Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission

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Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission in Caenorhabditis elegans

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21 January 2018

Dissecting docking and tethering of secretory vesicles at the target membrane.

1 reference

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21 January 2018

A complexin fusion clamp regulates spontaneous neurotransmitter release and synaptic growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.514273

21 January 2018

Domain 3a of Munc18-1 plays a crucial role at the priming stage of exocytosis.

1 reference

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21 January 2018

Caveolin-1 hydrophobic segment peptides insertion into membrane mimetic systems: role of proline residue

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21 January 2018

Structural and functional implications of a proline residue in the antimicrobial peptide gaegurin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.514273

21 January 2018

The Munc18-1 domain 3a loop is essential for neuroexocytosis but not for syntaxin-1A transport to the plasma membrane.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.514273

21 January 2018

Synaptotagmin-1 Docks Secretory Vesicles to Syntaxin-1/SNAP-25 Acceptor Complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.514273

21 January 2018

Energetics and dynamics of SNAREpin folding across lipid bilayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/24532794

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N- to C-Terminal SNARE Complex Assembly Promotes Rapid Membrane Fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/24532794

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The unc-18 gene encodes a novel protein affecting the kinetics of acetylcholine metabolism in the nematode Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/24532794

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.514273

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24532794%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24532794%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24532794%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

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