(Q30273613)

English

Hepatocyte nuclear factor (HNF)-4alpha induces expression of endothelial Fas ligand (FasL) to prevent cancer cell transmigration: a novel defense mechanism of endothelium against cancer metastasis

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scholarly article

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

Hepatocyte nuclear factor (HNF)-4alpha induces expression of endothelial Fas ligand (FasL) to prevent cancer cell transmigration: a novel defense mechanism of endothelium against cancer metastasis (English)

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

0 references

cancer metastasis

1 reference

based on heuristic

inferred from title

3

object named as

Takashi Kojima

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

author name string

Makoto Osanai

1

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

Hideki Chiba

2

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

Masato Fujibe

4

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

Kazuhide Kuwahara

5

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

Hiromichi Kimura

6

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

Masaaki Satoh

7

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

Norimasa Sawada

8

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

publication date

1 May 2002

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

number of pages

10

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inferred from page(s)

Japanese Journal of Cancer Research

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

93

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Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

5

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

532-541

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

Apoptosis: an early event in metastatic inefficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Inhibitor of the tissue-specific transcription factor HNF4, a potential regulator in early Xenopus development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Characterization of a novel cis-element that regulates Fas ligand expression in corneal endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Regulation of alpha1-antitrypsin gene expression in human intestinal epithelial cell line caco-2 by HNF-1alpha and HNF-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

TNFalpha regulation of Fas ligand expression on the vascular endothelium modulates leukocyte extravasation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Downregulation of Fas ligand by shedding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Phenobarbital causes apoptosis in conditionally immortalized mouse hepatocytes depending on deregulated c-myc expression: characterization of an unexpected effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Apoptosis by death factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

The DNA binding domain of hepatocyte nuclear factor 4 mediates cooperative, specific binding to DNA and heterodimerization with the retinoid X receptor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Enhanced paracellular barrier function of rat mesothelial cells partially protects against cancer cell penetration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Localization of 7H6 tight junction-associated antigen along the cell border of vascular endothelial cells correlates with paracellular barrier function against ions, large molecules, and cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

The pathogenesis of atherosclerosis: a perspective for the 1990s

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Regulation of apoptosis in the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Transcriptional activation by tetracyclines in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Effect of bcl-2 on Fas antigen-mediated cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Regulation of the Fas apoptotic cell death pathway by Abl.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

The role of APO-1-mediated apoptosis in the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

The Fas death factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Metastatic Inefficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

20 June 2018

Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927027

28 July 2018

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2002.TB01288.X

21 January 2018

A role for CD95 ligand in preventing graft rejection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2002.TB01288.X

21 January 2018

Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4α

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2002.TB01288.X

21 January 2018

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1 reference

https://pubmed.ncbi.nlm.nih.gov/12036449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12036449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide induces up-regulation of Fas in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12036449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

1 reference

https://pubmed.ncbi.nlm.nih.gov/12036449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas ligand in human serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/12036449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas ligand and immune evasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12036449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12036449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12036449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1349-7006.2002.TB01288.X

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5927027

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