(Q30275691)

English

A Phase 2, Double-Blind, Placebo-Controlled Randomized Trial Assessing the Efficacy of ABT-436, a Novel V1b Receptor Antagonist, for Alcohol Dependence

scientific article published on 23 September 2016

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scholarly article

1 reference

Europe PubMed Central

18 July 2018

http://europepmc.org/abstract/PMC/5506792

A Phase 2, Double-Blind, Placebo-Controlled Randomized Trial Assessing the Efficacy of ABT-436, a Novel V1b Receptor Antagonist, for Alcohol Dependence (English)

1 reference

Europe PubMed Central

18 July 2018

http://europepmc.org/abstract/PMC/5506792

phase II clinical trial

0 references

1 reference

based on heuristic

inferred from title

alcohol dependence

1 reference

based on heuristic

inferred from title

17

object named as

George F Koob

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http://europepmc.org/abstract/PMC/5506792

author name string

Megan L Ryan

1

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http://europepmc.org/abstract/PMC/5506792

Daniel E Falk

2

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http://europepmc.org/abstract/PMC/5506792

Joanne B Fertig

3

1 reference

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http://europepmc.org/abstract/PMC/5506792

Beatrice Rendenbach-Mueller

4

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http://europepmc.org/abstract/PMC/5506792

David A Katz

5

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Katherine A Tracy

6

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http://europepmc.org/abstract/PMC/5506792

Eric C Strain

7

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Kelly E Dunn

8

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Kyle Kampman

9

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http://europepmc.org/abstract/PMC/5506792

Elizabeth Mahoney

10

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http://europepmc.org/abstract/PMC/5506792

Domenic A Ciraulo

11

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http://europepmc.org/abstract/PMC/5506792

Laurie Sickles-Colaneri

12

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Nassima Ait-Daoud

13

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Bankole A Johnson

14

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Janet Ransom

15

1 reference

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http://europepmc.org/abstract/PMC/5506792

Charles Scott

16

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Raye Z Litten

18

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http://europepmc.org/abstract/PMC/5506792

language of work or name

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publication date

23 September 2016

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18 July 2018

http://europepmc.org/abstract/PMC/5506792

Neuropsychopharmacology

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http://europepmc.org/abstract/PMC/5506792

42

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5

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1012-1023

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Europe PubMed Central

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http://europepmc.org/abstract/PMC/5506792

Existing and Future Drugs for the Treatment of the Dark Side of Addiction

1 reference

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28 July 2018

2010 National and State Costs of Excessive Alcohol Consumption

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Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals

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Epidemiology of DSM-5 Alcohol Use Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions III.

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Cause-specific mortality risk in alcohol use disorder treatment patients: a systematic review and meta-analysis

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Neuronal nicotinic acetylcholine receptors are important targets for alcohol reward and dependence

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A double-blind, placebo-controlled trial assessing the efficacy of varenicline tartrate for alcohol dependence

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Evidence that vasopressin V1b receptors mediate the transition to excessive drinking in ethanol-dependent rats

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Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence.

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A double-blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal

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Neurokinin 1 receptor antagonism as a possible therapy for alcoholism

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Suppression of the HPA axis stress-response: implications for relapse

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Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress

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Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders.

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How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions

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Adult and geriatric normative data and validation of the profile of mood states

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Effects of naltrexone on alcohol self-administration in heavy drinkers.

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Naltrexone increases the latency to drink alcohol in social drinkers.

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Alterations in the hypothalamic-pituitary-adrenal axis in actively drinking alcoholics

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Neurocircuitry of stress: central control of the hypothalamo-pituitary-adrenocortical axis

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Clinical safety and hypothalamic-pituitary-adrenal axis effects of the arginine vasopressin type 1B receptor antagonist ABT-436.

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21 January 2018

Single-Dose Interaction Study of the Arginine Vasopressin Type 1B Receptor Antagonist ABT-436 and Alcohol in Moderate Alcohol Drinkers.

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Chronic nicotine activates stress/reward-related brain regions and facilitates the transition to compulsive alcohol drinking

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Acamprosate in the treatment of alcohol dependence

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Identifiers

10.1038/NPP.2016.214

1 reference

Europe PubMed Central

18 July 2018

http://europepmc.org/abstract/PMC/5506792

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24 November 2022

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1 reference

Europe PubMed Central

18 July 2018

http://europepmc.org/abstract/PMC/5506792

1 reference

Europe PubMed Central

18 July 2018

http://europepmc.org/abstract/PMC/5506792

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