(Q30276804)

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A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases

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scholarly article

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Europe PubMed Central

17 August 2017

A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases (English)

1 reference

Europe PubMed Central

17 August 2017

1 reference

based on heuristic

inferred from title

Suna Onengut-Gumuscu

18

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Soumya Raychaudhuri

22

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Jane Worthington

12

object named as

Jane Worthington

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object named as

Wei-Min Chen

17

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Solbritt Rantapää Dahlqvist

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Solbritt Rantapää Dahlqvist

11

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Kamil Slowikowski

object named as

Kamil Slowikowski

3

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15

object named as

Lars Klareskog

1 reference

Europe PubMed Central

17 August 2017

Peter K. Gregersen

10

object named as

Peter K Gregersen

1 reference

Europe PubMed Central

17 August 2017

16

object named as

Tom Huizinga

1 reference

Europe PubMed Central

17 August 2017

21

object named as

Naomi R Wray

1 reference

Europe PubMed Central

17 August 2017

1

object named as

Buhm Han

1 reference

Europe PubMed Central

17 August 2017

4

object named as

Eli Stahl

1 reference

Europe PubMed Central

17 August 2017

Dorothée Diogo

6

object named as

Dorothee Diogo

1 reference

Europe PubMed Central

17 August 2017

author name string

Jennie G Pouget

2

1 reference

Europe PubMed Central

17 August 2017

Cue Hyunkyu Lee

5

1 reference

Europe PubMed Central

17 August 2017

Xinli Hu

7

1 reference

Europe PubMed Central

17 August 2017

Yu Rang Park

8

1 reference

Europe PubMed Central

17 August 2017

Eunji Kim

9

1 reference

Europe PubMed Central

17 August 2017

Javier Martin

13

1 reference

Europe PubMed Central

17 August 2017

Steve Eyre

14

1 reference

Europe PubMed Central

17 August 2017

Stephen S Rich

19

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Europe PubMed Central

17 August 2017

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

20

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Europe PubMed Central

17 August 2017

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publication date

16 May 2016

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Europe PubMed Central

17 August 2017

Nature Genetics

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17 August 2017

48

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Europe PubMed Central

17 August 2017

7

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Europe PubMed Central

17 August 2017

803-810

1 reference

Europe PubMed Central

17 August 2017

An atlas of genetic correlations across human diseases and traits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Polygenic risk scores for schizophrenia and bipolar disorder predict creativity

1 reference

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3 June 2018

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

A new initiative on precision medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Biological insights from 108 schizophrenia-associated genetic loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

The genetics of major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Disentangling the heterogeneity of autism spectrum disorder through genetic findings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

The causes and consequences of genetic heterogeneity in cancer evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Pleiotropy in complex traits: challenges and strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Immune-mediated disease genetics: the shared basis of pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

A mega-analysis of genome-wide association studies for major depressive disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Abundant pleiotropy in human complex diseases and traits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Pervasive sharing of genetic effects in autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Diagnostic shifts during the decade following first admission for psychosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Subtypes of medulloblastoma have distinct developmental origins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

All you wanted to know about anti-CCP but were afraid to ask.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Meta-analysis of genome-wide association studies with overlapping subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Shared and distinct genetic variants in type 1 diabetes and celiac disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Prediction of individual genetic risk to disease from genome-wide association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

The International HapMap Project

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Diagnostic misclassification reduces the ability to detect linkage in inflammatory bowel disease genetic studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Major depression and generalized anxiety disorder. Same genes, (partly) different environments?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925284

3 June 2018

Implications of comorbidity and ascertainment bias for identifying disease genes.

1 reference

https://api.crossref.org/works/10.1038%2FNG.3572

21 January 2018

Value of anti-modified citrullinated vimentin and third-generation anti-cyclic citrullinated peptide compared with second-generation anti-cyclic citrullinated peptide and rheumatoid factor in predicting disease outcome in undifferentiated arthritis a

1 reference

https://api.crossref.org/works/10.1038%2FNG.3572

21 January 2018

Identifiers

10.1038/NG.3572

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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