(Q30278872)

11 August 2017

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases (English)

1 reference

11 August 2017

34

1 reference

20 June 2017

21

0 references

Soumya Raychaudhuri

Solbritt Rantapää-Dahlqvist

37

0 references

23

0 references

Alexandra Zhernakova

8

0 references

Jane Worthington

27

Jane Worthington

0 references

Aaron J Deutsch

Aaron J Deutsch

2

0 references

Tobias L. Lenz

Tobias L Lenz

1

0 references

Lam C. Tsoi

Lam C Tsoi

25

0 references

David A van Heel

David A van Heel

26

0 references

Stephen Eyre

Stephen Eyre

6

0 references

Javier Martin

Javier Martin

18

0 references

Markus M Nöthen

Markus M Nöthen

20

0 references

Dafna D. Gladman

15

Dafna D Gladman

1 reference

11 August 2017

10

Gonçalo Abecasis

1 reference

11 August 2017

29

Lars Klareskog

1 reference

11 August 2017

31

Peter K Gregersen

1 reference

11 August 2017

9

Tom W J Huizinga

1 reference

11 August 2017

3

Buhm Han

1 reference

11 August 2017

14

Andre Franke

1 reference

11 August 2017

36

Paul I W de Bakker

1 reference

11 August 2017

Javier Gutierrez-Achury

17

Javier Gutierrez-Achury

1 reference

11 August 2017

35

Shamil R Sunyaev

1 reference

11 August 2017

33

Stephen S Rich

1 reference

11 August 2017

19

Rajan P Nair

1 reference

11 August 2017

22

Proton Rahman

1 reference

11 August 2017

12

Guy E Boeckxstaens

1 reference

11 August 2017

16

Ines Gockel

1 reference

11 August 2017

28

Mira M Wouters

1 reference

11 August 2017

Xinli Hu

4

1 reference

11 August 2017

Yukinori Okada

5

1 reference

11 August 2017

Michael Knapp

7

1 reference

11 August 2017

Jessica Becker

11

1 reference

11 August 2017

Wei-Min Chen

13

1 reference

11 August 2017

Philip E Stuart

24

1 reference

11 August 2017

James T Elder

30

1 reference

11 August 2017

Johannes Schumacher

32

1 reference

11 August 2017

language of work or name

English

0 references

publication date

10 August 2015

1 reference

11 August 2017

1 reference

11 August 2017

47

1 reference

11 August 2017

9

1 reference

11 August 2017

1085-1090

1 reference

Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

The contribution of genetic variants to disease depends on the ruler

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

MHC Class II Polymorphisms, Autoreactive T-Cells, and Autoimmunity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Genetic insights into common pathways and complex relationships among immune-mediated diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Major histocompatibility complex genomics and human disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Imputing amino acid polymorphisms in human leukocyte antigens

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Genetics and epigenetics of rheumatoid arthritis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

HLA-DQA1 and HLA-DQB1 in Celiac disease predisposition: practical implications of the HLA molecular typing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Interrogating the major histocompatibility complex with high-throughput genomics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

MHC genotypes associate with resistance to a frog-killing fungus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Computational prediction of MHC II-antigen binding supports divergent allele advantage and explains trans-species polymorphism.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Allele interaction--single locus genetics meets regulatory biology

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Multi-locus models of genetic risk of disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

The rheumatoid arthritis HLA-DRB1 shared epitope

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Analysis of maternal-offspring HLA compatibility, parent-of-origin and non-inherited maternal effects for the classical HLA loci in type 1 diabetes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Does intra-individual major histocompatibility complex diversity keep a golden mean?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Practical aspects of imputation-driven meta-analysis of genome-wide association studies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

The Type 1 Diabetes Genetics Consortium

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Gene map of the extended human MHC.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Effect of human leukocyte antigen heterozygosity on infectious disease outcome: the need for allele-specific measures

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

MHC heterozygosity confers a selective advantage against multiple-strain infections

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Balanced polymorphism selected by genetic versus infectious human disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Heterozygote advantage for HLA class-II type in hepatitis B virus infection

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

The molecular basis of genetic dominance

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Preferential transmission of diabetic alleles within the HLA gene complex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

HLA heterozygosity contributes to susceptibility to rheumatoid arthritis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease

3 June 2018

1 reference

Genome-wide significant risk associations for mucinous ovarian carcinoma

21 January 2018

1 reference

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

21 January 2018

1 reference

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

21 January 2018

1 reference

Another explanation for apparent epistasis

21 January 2018

1 reference

Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases

21 January 2018

1 reference

Autoimmunity in rheumatoid arthritis: citrulline immunity and beyond

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552599

HLA-DRB1*0401/0404 genotype and rheumatoid arthritis: increased association in men, young age at onset, and disease severity

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26258845

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Preferential transmission of maternal allele with DQA1*0301-DQB1*0302 haplotype to affected offspring in families with type 1 diabetes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26258845

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Handbook of Statistical Genetics

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NG.3379

1 reference

Dimensions Publication ID

11 August 2017

0 references

1 reference

11 August 2017

1 reference