(Q30279123)

14 June 2017

Globular adiponectin ameliorates metabolic insulin resistance via AMPK-mediated restoration of microvascular insulin responses (English)

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14 June 2017

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Lina Zhao

1

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14 June 2017

Zhuo Fu

2

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14 June 2017

Jing Wu

3

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14 June 2017

Kevin W Aylor

4

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14 June 2017

Eugene J Barrett

5

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14 June 2017

Wenhong Cao

6

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14 June 2017

Zhenqi Liu

7

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14 June 2017

language of work or name

English

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publication date

24 June 2015

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14 June 2017

Journal of Physiology

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14 June 2017

593

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14 June 2017

17

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14 June 2017

4067-4079

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Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

14 June 2017

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The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action

21 January 2018

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The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

21 January 2018

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The stimulatory effect of globular adiponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjects

21 January 2018

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Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells.

21 January 2018

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Glucagon-like peptide 1 recruits microvasculature and increases glucose use in muscle via a nitric oxide-dependent mechanism

21 January 2018

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Angiotensin II receptors modulate muscle microvascular and metabolic responses to insulin in vivo

21 January 2018

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Activation of p38 mitogen-activated protein kinase abolishes insulin-mediated myocardial protection against ischemia-reperfusion injury

21 January 2018

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Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabetics

21 January 2018

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Obesity blunts insulin-mediated microvascular recruitment in human forearm muscle

21 January 2018

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The vasodilatory actions of insulin on resistance and terminal arterioles and their impact on muscle glucose uptake

21 January 2018

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Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

21 January 2018

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Impaired microvascular function in obesity: implications for obesity-associated microangiopathy, hypertension, and insulin resistance

21 January 2018

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Protein kinase A mediates glucagon-like peptide 1-induced nitric oxide production and muscle microvascular recruitment

21 January 2018

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Ranolazine recruits muscle microvasculature and enhances insulin action in rats

21 January 2018

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Adipose tissue adiponectin production and adiponectin serum concentration in human obesity and insulin resistance

21 January 2018

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Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

21 January 2018

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Contraction stimulates nitric oxide independent microvascular recruitment and increases muscle insulin uptake

21 January 2018

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Microvascular dysfunction in obesity: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension

21 January 2018

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Adiponectin and adiponectin receptors

21 January 2018

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Characterization of the arterial anatomy of the murine hindlimb: functional role in the design and understanding of ischemia models

21 January 2018

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Adiponectin abates diabetes-induced endothelial dysfunction by suppressing oxidative stress, adhesion molecules, and inflammation in type 2 diabetic mice

21 January 2018

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Adiponectin improves endothelial function in hyperlipidemic rats by reducing oxidative/nitrative stress and differential regulation of eNOS/iNOS activity

21 January 2018

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Reduced vascular responsiveness to adiponectin in hyperlipidemic rats--mechanisms and significance

21 January 2018

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Infusing lipid raises plasma free fatty acids and induces insulin resistance in muscle microvasculature

21 January 2018

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Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke

21 January 2018

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APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

21 January 2018

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Perivascular adipose tissue control of insulin-induced vasoreactivity in muscle is impaired in db/db mice

21 January 2018

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Adiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed rats

21 January 2018

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Globular adiponectin resistance develops independently of impaired insulin-stimulated glucose transport in soleus muscle from high-fat-fed rats

21 January 2018

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Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity

21 January 2018

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Endothelial function, vascular reactivity and gender differences in the cardiovascular system

21 January 2018

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Adenovirus-mediated adiponectin expression augments skeletal muscle insulin sensitivity in male Wistar rats

21 January 2018

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Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin

21 January 2018

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Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo

21 January 2018

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Insulin-mediated hemodynamic changes are impaired in muscle of Zucker obese rats

21 January 2018

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Adiponectin sensitizes insulin signaling by reducing p70 S6 kinase-mediated serine phosphorylation of IRS-1.

21 January 2018

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Insulin signaling stimulates insulin transport by bovine aortic endothelial cells

21 January 2018

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Losartan increases muscle insulin delivery and rescues insulin's metabolic action during lipid infusion via microvascular recruitment

21 January 2018

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Resveratrol recruits rat muscle microvasculature via a nitric oxide-dependent mechanism that is blocked by TNFα.

21 January 2018

1 reference

Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4575587

21 January 2018

Adiponectin is required for PPARγ-mediated improvement of endothelial function in diabetic mice.

26 November 2018

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A novel mechanism for vascular insulin resistance in normotensive young SHRs: hypoadiponectinemia and resultant APPL1 downregulation.

21 January 2018

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

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Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis

21 January 2018

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

21 January 2018

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Reduced cardioprotective action of adiponectin in high-fat diet-induced type II diabetic mice and its underlying mechanisms.

21 January 2018

1 reference

Globular adiponectin enhances muscle insulin action via microvascular recruitment and increased insulin delivery

21 January 2018

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Adiponectin, an adipocyte-derived protein.

21 January 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4575587

Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

26 November 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4575587

Globular and full-length adiponectin induce NO-dependent vasodilation in resistance arteries of Zucker lean but not Zucker diabetic fatty rats

26 November 2018

1 reference

12 December 2020

Adiponectin replenishment ameliorates obesity-related hypertension

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12 December 2020

Globular and full-length forms of adiponectin mediate specific changes in glucose and fatty acid uptake and metabolism in cardiomyocytes

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12 December 2020

Adiponectin resistance exacerbates insulin resistance in insulin receptor transgenic/knockout mice

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12 December 2020

Identifiers

DOI

10.1113/JP270371

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14 June 2017

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