(Q36910745)

17 August 2017

1 reference

title

Microvascular dysfunction in obesity: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension (English)

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Coenraad Dirk Adriaan Stehouwer

17 August 2017

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series ordinal

6

object named as

Coen D A Stehouwer

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17 August 2017

4

Erik H Serné

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17 August 2017

1

Amy M Jonk

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17 August 2017

Alfons J H M Houben

2

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17 August 2017

Renate T de Jongh

series ordinal

3

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17 August 2017

Nicoloaas C Schaper

series ordinal

5

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17 August 2017

publication date

1 August 2007

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17 August 2017

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17 August 2017

volume

22

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17 August 2017

page(s)

252-260

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Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers for prevention of type 2 diabetes: a meta-analysis of randomized clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Impaired skeletal muscle and skin microcirculatory function in human obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

PROLONGED INFUSIONS OF ANGIOTENSIN II AND NOREPINEPHRINE AND BLOOD PRESSURE, ELECTROLYTE BALANCE, AND ALDOSTERONE AND CORTISOL SECRETION IN NORMAL MAN AND IN CIRRHOSIS WITH ASCITES.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Cardiovascular actions of insulin in humans. Implications for insulin sensitivity and vascular tone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Hemodynamic actions of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Role of blood flow in the regulation of muscle glucose uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Endothelial dysfunction, inflammation, and insulin resistance: a focus on subjects at risk for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Enhanced vascular activity of endogenous endothelin-1 in obese hypertensive patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Adiponectin: more than just another fat cell hormone?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Vascular and endocrine control of muscle metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Blood flow and muscle metabolism: a focus on insulin action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Obesity blunts insulin-mediated microvascular recruitment in human forearm muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Physiologic hyperinsulinemia enhances human skeletal muscle perfusion by capillary recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Angiotensin II receptor blocker valsartan suppresses reactive oxygen species generation in leukocytes, nuclear factor-kappa B, in mononuclear cells of normal subjects: evidence of an antiinflammatory action

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Physiological hyperinsulinaemia increases intramuscular microvascular reactive hyperaemia and vasomotion in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Free fatty acid levels modulate microvascular function: relevance for obesity-associated insulin resistance, hypertension, and microangiopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Impaired microvascular function in obesity: implications for obesity-associated microangiopathy, hypertension, and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

The role of adipokines as regulators of skeletal muscle fatty acid metabolism and insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Weight loss and the renin-angiotensin-aldosterone system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

The adipose-tissue renin-angiotensin-aldosterone system: role in the metabolic syndrome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Vasoconstrictor effects of insulin in skeletal muscle arterioles are mediated by ERK1/2 activation in endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Physiological concentrations of insulin induce endothelin-dependent vasoconstriction of skeletal muscle resistance arteries in the presence of tumor necrosis factor-alpha dependence on c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Prevalence and Trends in Obesity Among US Adults, 1999-2000

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Hypertension-independent microvascular rarefaction in the obese Zucker rat model of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Impaired skeletal muscle perfusion in obese Zucker rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Reduced nitric oxide bioavailability contributes to skeletal muscle microvessel rarefaction in the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Exercise training blunts microvascular rarefaction in the metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Spotlight on renin. The renin system, salt-sensitivity and metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Associations of body composition with type 2 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Signaling crosstalk angiotensin II receptor subtypes and insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Retinal vessel diameters and risk of hypertension: the Rotterdam Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. A novel mechanism for insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Investigation of oxidant stress and vasodepression to glyceryl trinitrate in the obese Zucker rat in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Effect of hereditary obesity on renal expressions of NO synthase, caveolin-1, AKt, guanylate cyclase, and calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Reactive oxygen species are critical in the oleic acid-mediated mitogenic signaling pathway in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Hemostatic markers of endothelial dysfunction and risk of incident type 2 diabetes: the Framingham Offspring Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Long-term treatment with losartan versus atenolol improves insulin sensitivity in hypertension: ICARUS, a LIFE substudy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Physiology of local renin-angiotensin systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Obesity and body fat distribution induce endothelial dysfunction by oxidative stress: protective effect of vitamin C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Hypertriglyceridemia and hyperinsulinemia are potent inducers of endothelin-1 release in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Mechanisms of Disease: endothelial dysfunction in insulin resistance and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Acute vasoconstriction-induced insulin resistance in rat muscle in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Hemodynamic actions of insulin in rat skeletal muscle: evidence for capillary recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Banting lecture 1988. Role of insulin resistance in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

A high-fat, refined-carbohydrate diet induces endothelial dysfunction and oxidant/antioxidant imbalance and depresses NOS protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Effects of angiotensin II on adipose conversion and expression of genes of the renin-angiotensin system in human preadipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Capillary recruitment is impaired in essential hypertension and relates to insulin's metabolic and vascular actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Direct evidence for insulin-induced capillary recruitment in skin of healthy subjects during physiological hyperinsulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Microvascular function relates to insulin sensitivity and blood pressure in normal subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Unraveling the cellular mechanism of insulin resistance in humans: new insights from magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Pressor and subpressor angiotensin II administration. Two experimental models of hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Endothelial dysfunction: role in obesity-related disorders and the early origins of CVD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Diabetes, hypertension, and cardiovascular disease: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Impact of obesity and insulin resistance on vasomotor tone: nitric oxide and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

The microcirculation and hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Nicotinic acid adenine dinucleotide phosphate: a new intracellular second messenger?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

The contribution of skeletal muscle tumor necrosis factor-alpha to insulin resistance and hypertension in fructose-fed rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Intracellular mechanisms involved in vascular remodelling of resistance arteries in hypertension: role of angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

The effect of weight reduction on blood pressure, plasma renin activity, and plasma aldosterone levels in obese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Cross-talk between the insulin and angiotensin signaling systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

How monitoring of the microcirculation may help us at the bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Insulin-mediated hemodynamic changes are impaired in muscle of Zucker obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Inhibition of the renin-angiotensin system prevents free fatty acid-induced acute endothelial dysfunction in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Insulin-induced vasodilatation: physiology or pharmacology?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

"Vasocrine" signalling from perivascular fat: a mechanism linking insulin resistance to vascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Insulin sensitivity of muscle capillary recruitment in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

TNF-alpha acutely inhibits vascular effects of physiological but not high insulin or contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

Adipose depot-specific modulation of angiotensinogen gene expression in diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00012.2007

10.1152/PHYSIOL.00012.2007

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference