(Q30311208)

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Soluble urokinase-type plasminogen activator receptor inhibits cancer cell growth and invasion by direct urokinase-independent effects on cell signaling

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scholarly article

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Europe PubMed Central

PubMed publication ID

16 June 2017

Soluble urokinase-type plasminogen activator receptor inhibits cancer cell growth and invasion by direct urokinase-independent effects on cell signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

1 reference

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author name string

Minji Jo

1

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

Keena S Thomas

2

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

Lihua Wu

3

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

Steven L Gonias

4

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

language of work or name

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publication date

8 September 2003

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

16 June 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

47

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

46692-46698

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

uPAR: a versatile signalling orchestrator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

The urokinase-type plasminogen activator system in cancer metastasis: a review

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Regulation of integrin function by the urokinase receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Urokinase receptors promote beta1 integrin function through interactions with integrin alpha3beta1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Regulation of Rac1 activation by the low density lipoprotein receptor-related protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Epidermal growth factor receptor-dependent and -independent cell-signaling pathways originating from the urokinase receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Structure-function relationships in the receptor for urokinase-type plasminogen activator. Comparison to other members of the Ly-6 family and snake venom alpha-neurotoxins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Domain interplay in the urokinase receptor. Requirement for the third domain in high affinity ligand binding and demonstration of ligand contact sites in distinct receptor domains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Domain 1 of the urokinase receptor (uPAR) is required for uPAR-mediated cell binding to vitronectin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Urokinase-type plasminogen activator stimulates the Ras/Extracellular signal-regulated kinase (ERK) signaling pathway and MCF-7 cell migration by a mechanism that requires focal adhesion kinase, Src, and Shc. Rapid dissociation of GRB2/Sps-Shc compl

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

A ligand-free, soluble urokinase receptor is present in the ascitic fluid from patients with ovarian cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Soluble urokinase receptor released from human carcinoma cells: a plasma parameter for xenograft tumour studies.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Reduction of breast carcinoma tumor growth and lung colonization by overexpression of the soluble urokinase-type plasminogen activator receptor (CD87).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

High level synthesis of recombinant soluble urokinase receptor (CD87) by ovarian cancer cells reduces intraperitoneal tumor growth and spread in nude mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Recombinant soluble urokinase receptor as a scavenger for urokinase-type plasminogen activator (uPA). Inhibition of proliferation and invasion of human ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Embryonic fibroblasts that are genetically deficient in low density lipoprotein receptor-related protein demonstrate increased activity of the urokinase receptor system and accelerated migration on vitronectin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Regulation of cell motility by mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Urokinase plasminogen activator: a prognostic marker in multiple types of cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Prognostic significance of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in primary breast cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

The very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

The cleavage of the urokinase receptor regulates its multiple functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308808200

21 January 2018

Identifiers

10.1074/JBC.M308808200

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

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