(Q30332236)

18 June 2017

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title

Protein formulation and fill-finish operations. (English)

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18 June 2017

Sugunakar Y Patro

1

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18 June 2017

Erwin Freund

series ordinal

2

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18 June 2017

Byeong S Chang

series ordinal

3

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18 June 2017

publication date

1 January 2002

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Biotechnology Annual Review

18 June 2017

published in

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18 June 2017

volume

8

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18 June 2017

page(s)

55-84

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The mechanisms of irreversible enzyme inactivation at 100C.

18 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Maintenance of quaternary structure in the frozen state stabilizes lactate dehydrogenase during freeze-drying

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Mechanism of protein salting in and salting out by divalent cation salts: balance between hydration and salt binding

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

The stabilization of proteins by osmolytes

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Mechanism of poly(ethylene glycol) interaction with proteins.

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Protein--solvent interactions in pharmaceutical formulations

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Influence of heavy metal ions on antibodies and immune complexes investigated by dynamic light scattering and enzyme-linked immunosorbent assay

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Monomeric insulins and their experimental and clinical implications

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

An infrared spectroscopic study of the interactions of carbohydrates with dried proteins

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Rational design of stable lyophilized protein formulations: some practical advice

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Development of an efficient single-step freeze-drying cycle for protein formulations.

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Surface-induced denaturation of proteins during freezing and its inhibition by surfactants

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7 January 2021

Physical factors affecting the storage stability of freeze-dried interleukin-1 receptor antagonist: glass transition and protein conformation

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Techniques for assessing the effects of pharmaceutical excipients on the aggregation of porcine growth hormone

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Pressure-induced molten globule state of cholinesterase

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Dominant forces in protein folding

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Effect of freezing on aggregation of human growth hormone

1 reference

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7 January 2021

Mechanisms of photosensitized oxidation. There are several different types of photosensitized oxidation which may be important in biological systems.

1 reference

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7 January 2021

Subzero-temperature preservation of reactive fluids in the undercooled state. II. The effect on the oxidation of ascorbic acid of freeze concentration and undercooling.

1 reference

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7 January 2021

The surface coagulation of proteins during shaking

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Measurement of glass transition temperatures of freeze-concentrated solutes by differential scanning calorimetry

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https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Metal-catalyzed oxidation of human growth hormone: modulation by solvent-induced changes of protein conformation

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Some factors in the interpretation of protein denaturation

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7 January 2021

Effect of Tween 20 on freeze-thawing- and agitation-induced aggregation of recombinant human factor XIII

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Stability of protein pharmaceuticals

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Spread monolayers of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Role of aggregated human growth hormone (hGH) in development of antibodies to hGH

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Pressure-induced structural changes of pig heart lactic dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

An improved microscope stage for direct observation of freezing and freeze drying

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Metal ion interactions with bovine prothrombin and prothrombin fragment 1. Stoichiometry of binding, protein self-association, and conformational change induced by a variety of metal ions

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Structural changes at the heme induced by freezing hemoglobin

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

The effects of formulation variables on the stability of freeze-dried human growth hormone

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Inactivation mechanism of tetrameric beta-galactosidase by gamma-rays involves both fragmentation and temperature-dependent denaturation of protomers.

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Dehydration-induced conformational transitions in proteins and their inhibition by stabilizers

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Stability of proteins: small globular proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Cold denaturation of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Phase separation of excipients during lyophilization: effects on protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Deamidation of glutaminyl residues: dependence on pH, temperature, and ionic strength

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Effect of an exposure to chloramine-T on the immunoreactivity of glucagon

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Biological characterization of charge isomers of human growth hormone

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

1 reference

7 January 2021

Effect of freezing on the pH and composition of sodium and potassium phosphate solutions; the reciprocal system KH2PO4-Na2-HPO4-H2O

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

The effect of addition of sodium and potassium chloride to the reciprocal system: KH2PO4-Na2HPO4-H2O on pH and composition during freezing

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Mutations and off-pathway aggregation of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Pressure effects on protein secondary structure and hydrogen deuterium exchange in chymotrypsinogen: a Fourier transform infrared spectroscopic study

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Nonenzymatic Deamidation of Asparaginyl and Glutaminyl Residues in Protein

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

Pressure-denatured state of Escherichia coli ribonuclease HI as monitored by Fourier transform infrared and NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1387-2656%2802%2908004-3

7 January 2021

10.1016/S1387-2656(02)08004-3

Identifiers

DOI

1 reference

18 June 2017

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