(Q30344068)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Human immunodeficiency virus type 1 Nef protein mediates neural cell death: a neurotoxic role for IP-10 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

1 reference

1

1 reference

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4 January 2020

Michael John Gill

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Christopher Power

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

Scot Henry

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Tiona Todoruk

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Andrea Sullivan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Claudia Silva

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Sean B Rourke

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Janet Holden

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Justin C McArthur

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

language of work or name

English

0 references

publication date

1 November 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

number of pages

17

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inferred from page(s)

published in

Virology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

329

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

302-318

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

4 January 2020

cites work

2 references

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Vpr Is Preferentially Targeted by CTL During HIV-1 Infection

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Nef: agent of cell subversion

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Chemokines and viral diseases of the central nervous system

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Interferon-independent, human immunodeficiency virus type 1 gp120-mediated induction of CXCL10/IP-10 gene expression by astrocytes in vivo and in vitro

7 January 2021

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Replication of different clones of human immunodeficiency virus type 1 in primary fetal human astrocytes: enhancement of viral gene expression by Nef.

7 January 2021

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Up-regulation of proteinase-activated receptor 1 expression in astrocytes during HIV encephalitis

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Defective nef alleles in a cohort of hemophiliacs with progressing and nonprogressing HIV-1 infection

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Highly productive infection with pseudotyped human immunodeficiency virus type 1 (HIV-1) indicates no intracellular restrictions to HIV-1 replication in primary human astrocytes

7 January 2021

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Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia

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HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy

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The plasma membrane as a combat zone in the HIV battlefield

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Live and let die: Nef functions beyond HIV replication

7 January 2021

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Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization.

7 January 2021

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Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions

7 January 2021

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Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein

7 January 2021

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Microglia as mediators of inflammatory and degenerative diseases

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Restricted HIV-1 infection of human astrocytes: potential role of nef in the regulation of virus replication.

7 January 2021

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Nef 27, but not the Nef 25 isoform of human immunodeficiency virus-type 1 pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells

7 January 2021

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Refined solution structure and backbone dynamics of HIV-1 Nef.

7 January 2021

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Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

7 January 2021

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The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.

7 January 2021

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Astrocyte apoptosis induced by HIV-1 transactivation of the c-kit protooncogene

7 January 2021

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The HNRC 500--neuropsychology of HIV infection at different disease stages. HIV Neurobehavioral Research Center.

7 January 2021

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A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage

7 January 2021

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Microglia-specific localisation of a novel calcium binding protein, Iba1

7 January 2021

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Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus-type 1 (HIV-1) infection. Report of a Working Group of the American Academy of Neurology AIDS Task Force

7 January 2021

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Coreceptor phenotype of natural human immunodeficiency virus with nef deleted evolves in vivo, leading to increased virulence

7 January 2021

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HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors

7 January 2021

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Envelope gene-mediated neurovirulence in feline immunodeficiency virus infection: induction of matrix metalloproteinases and neuronal injury

7 January 2021

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Pathways to neuronal injury and apoptosis in HIV-associated dementia.

7 January 2021

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Cardiac disease in transgenic mice expressing human immunodeficiency virus-1 nef in cells of the immune system

7 January 2021

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Neurocognitive symptoms and impairment in an HIV community clinic

7 January 2021

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Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

7 January 2021

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Stable expression of HIV-1 Nef induces changes in growth properties and activation state of human astrocytes

7 January 2021

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HIV-1 Nef co-localizes with the astrocyte-specific cytoskeleton protein GFAP in persistently nef-expressing human astrocytes

7 January 2021

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Identification of a T cell chemotactic factor in the cerebrospinal fluid of HIV-1-infected individuals as interferon-gamma inducible protein 10.

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Mapping of a neurovirulence determinant within the envelope protein of a polytropic murine retrovirus: induction of central nervous system disease by low levels of virus

7 January 2021

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7 January 2021

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7 January 2021

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Abundant expression of HIV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia.

7 January 2021

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7 January 2021

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HIV type 1 nef gene inhibits tumor necrosis factor alpha-induced apoptosis and promotes cell proliferation through the action of MAPK and JNK in human glial cells

7 January 2021

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Overexpression of nef as a marker for restricted HIV-1 infection of astrocytes in postmortem pediatric central nervous tissues.

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system.

7 January 2021

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HIV dementia patients exhibit reduced viral neutralization and increased envelope sequence diversity in blood and brain

7 January 2021

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Human immunodeficiency virus type 1 envelope-mediated neuropathogenesis: targeted gene delivery by a Sindbis virus expression vector

7 January 2021

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Reduced prevalence of the CCR5 delta32 heterozygous genotype in human immunodeficiency virus-infected individuals with AIDS dementia complex

7 January 2021

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Escape from the immune system

7 January 2021

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Immunopathogenesis of HIV-associated dementia

7 January 2021

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Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia

7 January 2021

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Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes: in vitro ERK1/2 activation and role in Alzheimer's disease

7 January 2021

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HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration

7 January 2021

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Heterogeneity of Nef proteins in cells infected with human immunodeficiency virus type 1.

7 January 2021

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Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes

7 January 2021

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7 January 2021

Neuronal death induced by brain-derived human immunodeficiency virus type 1 envelope genes differs between demented and nondemented AIDS patients

1 reference

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7 January 2021

Detection of HIV‐1 DNA in Microglia/ Macrophages, Astrocytes and Neurons Isolated from Brain Tissue with HIV‐1 Encephalitis by Laser Capture Microdissection

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7 January 2021

10.1016/J.VIROL.2004.08.024

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15518810%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference