(Q30350727)

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In silico whole-genome scanning of cancer-associated nonsynonymous SNPs and molecular characterization of a dynein light chain tumour variant.

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Europe PubMed Central

PubMed publication ID

20 June 2017

In silico whole-genome scanning of cancer-associated nonsynonymous SNPs and molecular characterization of a dynein light chain tumour variant. (English)

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Europe PubMed Central

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20 June 2017

whole genome sequencing

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Manolo Gouy

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20 June 2017

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Mingjie Zhang

8

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Abdel Aouacheria

1

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20 June 2017

Vincent Navratil

2

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20 June 2017

Wenyu Wen

3

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20 June 2017

Ming Jiang

4

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20 June 2017

Dominique Mouchiroud

5

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20 June 2017

Christian Gautier

6

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20 June 2017

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1 September 2005

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20 June 2017

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20 June 2017

24

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20 June 2017

6133-6142

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Europe PubMed Central

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20 June 2017

Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: structure-based assessment of amino acid variation

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Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

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Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain

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Protein inhibitor of neuronal nitric-oxide synthase, PIN, binds to a 17-amino acid residue fragment of the enzyme

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Understanding missense mutations in the BRCA1 gene: an evolutionary approach

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Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8

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Integrins: roles in cancer development and as treatment targets

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Structure of the PIN/LC8 dimer with a bound peptide

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Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes

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Altered cellular responses by varying expression of a ribosomal protein gene: sequential coordination of enhancement and suppression of ribosomal protein S3a gene expression induces apoptosis

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Genome wide in silico SNP-tumor association analysis

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Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc

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Does the ribosome translate cancer?

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Structural location of disease-associated single-nucleotide polymorphisms

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Sequence-based cancer genomics: progress, lessons and opportunities

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Structure of the monomeric 8-kDa dynein light chain and mechanism of the domain-swapped dimer assembly

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21 January 2018

SNPs, protein structure, and disease.

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Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity

1 reference

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Repression of in vivo growth of Myc/Ras transformed tumor cells by Mad1.

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Variations on a theme: cataloging human DNA sequence variation

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Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes

1 reference

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The Hallmarks of Cancer

1 reference

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PIN: an associated protein inhibitor of neuronal nitric oxide synthase

1 reference

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7 January 2021

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Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein

1 reference

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Search for in vivo somatic mutations in the mitotic checkpoint gene, hMAD1, in human lung cancers

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Functional significance of conserved amino acid residues

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Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

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Integration of genome data and protein structures: prediction of protein folds, protein interactions and "molecular phenotypes" of single nucleotide polymorphisms

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Cysteine cathepsins (proteases)--on the main stage of cancer?

1 reference

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Dynein light chain 1, a p21-activated kinase 1-interacting substrate, promotes cancerous phenotypes

1 reference

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7 January 2021

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Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function

1 reference

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7 January 2021

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10.1038/SJ.ONC.1208745

1 reference

Europe PubMed Central

PubMed publication ID

20 June 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 June 2017

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