(Q30352594)

20 June 2017

title

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. (English)

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20 June 2017

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Pablo Bifani

2

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Mary Jackson

object named as

Mary Jackson

14

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author name string

Kevin Pethe

1

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Jichan Jang

3

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Sunhee Kang

4

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Seijin Park

5

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Sujin Ahn

6

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Jan Jiricek

7

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Juyoung Jung

8

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Hee Kyoung Jeon

9

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Jonathan Cechetto

10

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Thierry Christophe

11

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20 June 2017

Honggun Lee

12

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Marie Kempf

13

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Anne J Lenaerts

15

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Ha Pham

16

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Victoria Jones

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Min Jung Seo

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Young Mi Kim

19

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20 June 2017

Mooyoung Seo

20

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Jeong Jea Seo

21

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Dongsik Park

22

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Yoonae Ko

23

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Inhee Choi

24

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Ryangyeo Kim

25

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Se Yeon Kim

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SeungBin Lim

27

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Seung-Ae Yim

28

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20 June 2017

Jiyoun Nam

29

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20 June 2017

Hwankyu Kang

30

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20 June 2017

Haejin Kwon

31

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Chun-Taek Oh

32

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20 June 2017

Yoojin Cho

33

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Yunhee Jang

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Junghwan Kim

35

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Adeline Chua

36

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Bee Huat Tan

37

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Mahesh B Nanjundappa

38

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Srinivasa P S Rao

39

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Whitney S Barnes

40

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René Wintjens

41

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John R Walker

42

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Sylvie Alonso

43

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Saeyeon Lee

44

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20 June 2017

Jungjun Kim

45

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Soohyun Oh

46

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20 June 2017

Taegwon Oh

47

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20 June 2017

Ulf Nehrbass

48

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20 June 2017

Sung-Jun Han

49

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20 June 2017

Zaesung No

50

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20 June 2017

Jinhwa Lee

51

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Priscille Brodin

52

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20 June 2017

Sang-Nae Cho

53

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20 June 2017

Kiyean Nam

54

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20 June 2017

Jaeseung Kim

55

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20 June 2017

language of work or name

English

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publication date

4 August 2013

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20 June 2017

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20 June 2017

volume

19

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20 June 2017

issue

9

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20 June 2017

page(s)

1157-1160

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Confronting multidrug-resistant tuberculosis

20 June 2017

cites work

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A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

21 January 2018

1 reference

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

21 January 2018

1 reference

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

21 January 2018

1 reference

Early bactericidal activity and pharmacokinetics of PA-824 in smear-positive tuberculosis patients

21 January 2018

1 reference

Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance.

21 January 2018

1 reference

Delamanid for multidrug-resistant pulmonary tuberculosis

21 January 2018

1 reference

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors

21 January 2018

1 reference

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

21 January 2018

1 reference

Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening.

21 January 2018

1 reference

Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism

21 January 2018

1 reference

Regiospecific synthesis of 3-substituted imidazo[1,2-a]pyridines, imidazo[1,2-a]pyrimidines, and imidazo[1,2-c]pyrimidine

21 January 2018

1 reference

The challenge of new drug discovery for tuberculosis

21 January 2018

1 reference

Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis

21 January 2018

1 reference

Activities of TMC207, rifampin, and pyrazinamide against Mycobacterium tuberculosis infection in guinea pigs

21 January 2018

1 reference

Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB

21 January 2018

1 reference

Function of the cytochrome bc1-aa3 branch of the respiratory network in mycobacteria and network adaptation occurring in response to its disruption

21 January 2018

1 reference

Genes required for mycobacterial growth defined by high density mutagenesis

21 January 2018

1 reference

Advent of Imidazo[1,2-a]pyridine-3-carboxamides with Potent Multi- and Extended Drug Resistant Antituberculosis Activity

21 January 2018

1 reference

A high-throughput screen to identify inhibitors of ATP homeostasis in non-replicating Mycobacterium tuberculosis

21 January 2018

1 reference

X-ray structure of the dimeric cytochrome bc(1) complex from the soil bacterium Paracoccus denitrificans at 2.7-Å resolution

21 January 2018

1 reference

Inhibitor-complexed structures of the cytochrome bc1 from the photosynthetic bacterium Rhodobacter sphaeroides

21 January 2018

1 reference

Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment

21 January 2018

1 reference

Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex

21 January 2018

1 reference

Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques

21 January 2018

1 reference

High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery

21 January 2018

1 reference

Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis

21 January 2018

1 reference

The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

21 January 2018

1 reference

Diarylquinolines are bactericidal for dormant mycobacteria as a result of disturbed ATP homeostasis

21 January 2018

1 reference

Microtiter plate assays for inhibition of human, drug-metabolizing cytochromes P450

21 January 2018

1 reference

12 December 2020

National survey of drug-resistant tuberculosis in China

1 reference

12 December 2020

Multicenter study of MTT and resazurin assays for testing susceptibility to first-line anti-tuberculosis drugs.

1 reference

12 December 2020

Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3- hydroxy-1,4-naphthoquinone (566C80)

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12 December 2020

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

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12 December 2020

Use of specific inhibitors on the mitochondrial bc1 complex

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12 December 2020

Identifiers

DOI

10.1038/NM.3262

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Dimensions Publication ID

20 June 2017

1052261221

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