(Q30370600)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

title

NMDAR inhibition-independent antidepressant actions of ketamine metabolites (English)

1 reference

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3 April 2020

3

1 reference

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3 April 2020

Greg Elmer

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Craig J Thomas

18

1 reference

ORCID Public Data File 2021

author name string

Panos Zanos

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Ruin Moaddel

2

1 reference

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3 April 2020

Polymnia Georgiou

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Jonathan Fischell

5

1 reference

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3 April 2020

Manickavasagom Alkondon

7

1 reference

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3 April 2020

Peixiong Yuan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Heather J Pribut

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Nagendra S Singh

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Katina S S Dossou

11

1 reference

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3 April 2020

Yuhong Fang

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Xi-Ping Huang

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Cheryl L Mayo

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Irving W Wainer

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Edson X Albuquerque

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Scott M Thompson

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Carlos A Zarate

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Todd D Gould

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

language of work or name

English

0 references

publication date

4 May 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

volume

533

1 reference

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3 April 2020

issue

7604

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

page(s)

481-486

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

3 April 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Evidence that Subanesthetic Doses of Ketamine Cause Sustained Disruptions of NMDA and AMPA-Mediated Frontoparietal Connectivity in Humans

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

The Prodrug 4-Chlorokynurenine Causes Ketamine-Like Antidepressant Effects, but Not Side Effects, by NMDA/GlycineB-Site Inhibition.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

The distribution and clearance of (2S,6S)-hydroxynorketamine, an active ketamine metabolite, in Wistar rats

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Sex differences in the rapid and the sustained antidepressant-like effects of ketamine in stress-naïve and "depressed" mice exposed to chronic mild stress

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

BDNF release is required for the behavioral actions of ketamine

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Anti-anhedonic effect of ketamine and its neural correlates in treatment-resistant bipolar depression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Requirement of AMPA receptor stimulation for the sustained antidepressant activity of ketamine and LY341495 during the forced swim test in rats

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Effects of striatal ΔFosB overexpression and ketamine on social defeat stress-induced anhedonia in mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Using deuterium in drug discovery: leaving the label in the drug

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Adolescent cannabinoid exposure permanently suppresses cortical oscillations in adult mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Sub-anesthetic concentrations of (R,S)-ketamine metabolites inhibit acetylcholine-evoked currents in α7 nicotinic acetylcholine receptors.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Stereoselective and regiospecific hydroxylation of ketamine and norketamine

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

3 June 2018

Ketamine use: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Chronux: a platform for analyzing neural signals

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

The female urine sniffing test: a novel approach for assessing reward-seeking behavior in rodents.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R)

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Inhibition-based rhythms: experimental and mathematical observations on network dynamics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Antidepressant effects of ketamine in depressed patients

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Studies on the biotransformation of ketamine. 1-Identification of metabolites produced in vitro from rat liver microsomal preparations.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Comparative pharmacology in the rat of ketamine and its two principal metabolites, norketamine and (Z)-6-hydroxynorketamine.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

Norketamine, the main metabolite of ketamine, is a non-competitive NMDA receptor antagonist in the rat cortex and spinal cord.

3 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE17998

Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE17998

Sex differences in the antidepressant-like effects of ketamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE17998

Involvement of N-methyl-D-aspartate (NMDA) receptors in noncompetitive NMDA receptor antagonist-induced hyperlocomotion in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE17998

Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE17998

Role of the NMDA receptor NR2B subunit in the discriminative stimulus effects of ketamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE17998

Chronic ethanol exposure alters MK-801 binding sites in the cerebral cortex of the near-term fetal guinea pig.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE17998

Gamma oscillations induced by kainate receptor activation in the entorhinal cortex in vitro.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922311

26 November 2018

Identifiers

DOI

10.1038/NATURE17998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27144355%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference