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Allosteric regulation and catalysis emerge via a common route.
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scholarly article
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Europe PubMed Central
PubMed ID
18641628
retrieved
21 June 2017
review article
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Europe PubMed Central
title
Allosteric regulation and catalysis emerge via a common route.
(English)
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Europe PubMed Central
PubMed ID
18641628
retrieved
21 June 2017
author name string
Nina M Goodey
series ordinal
1
1 reference
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Europe PubMed Central
PubMed ID
18641628
retrieved
21 June 2017
Stephen J Benkovic
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2
1 reference
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Europe PubMed Central
PubMed ID
18641628
retrieved
21 June 2017
publication date
1 August 2008
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Europe PubMed Central
PubMed ID
18641628
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21 June 2017
published in
Nature Chemical Biology
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Europe PubMed Central
PubMed ID
18641628
retrieved
21 June 2017
volume
4
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Europe PubMed Central
PubMed ID
18641628
retrieved
21 June 2017
page(s)
474-482
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Europe PubMed Central
PubMed ID
18641628
retrieved
21 June 2017
issue
8
1 reference
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Europe PubMed Central
PubMed ID
18641628
retrieved
21 June 2017
cites work
ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The origin of protein interactions and allostery in colocalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The dynamic energy landscape of dihydrofolate reductase catalysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of enzyme motions by solution NMR relaxation dispersion.
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanism of rate-limiting motions in enzyme function.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamic personalities of proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A hierarchy of timescales in protein dynamics is linked to enzyme catalysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The changing landscape of protein allostery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Network of coupled promoting motions in enzyme catalysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Network analysis of protein dynamics
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
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inferred from DOI database lookup
Allostery without conformational change. A plausible model
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is allostery an intrinsic property of all dynamic proteins?
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of dynamics in allosteric regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Catalysis and binding of cyclophilin A with different HIV-1 capsid constructs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for flexibility in the function of ribonuclease A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 protease: structure, dynamics, and inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A solution NMR study of the binding kinetics and the internal dynamics of an HIV-1 protease-substrate complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid structural fluctuations of the free HIV protease flaps in solution: relationship to crystal structures and comparison with predictions of dynamics calculations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solution NMR and computer simulation studies of active site loop motion in triosephosphate isomerase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Free-energy landscape of enzyme catalysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Backbone dynamics in dihydrofolate reductase complexes: role of loop flexibility in the catalytic mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intrinsic motions along an enzymatic reaction trajectory
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
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Functional dynamics of human FKBP12 revealed by methyl 13C rotating frame relaxation dispersion NMR spectroscopy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
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Slow internal dynamics in proteins: application of NMR relaxation dispersion spectroscopy to methyl groups in a cavity mutant of T4 lysozyme
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
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Distribution of molecular size within an unfolded state ensemble using small-angle X-ray scattering and pulse field gradient NMR techniques
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
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Intrinsic disorder as a mechanism to optimize allosteric coupling in proteins
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
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The linkage between protein folding and functional cooperativity: two sides of the same coin?
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
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Local motions in a benchmark of allosteric proteins.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
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Ligand binding and internal equilibiums in proteins
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
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Can allosteric regulation be predicted from structure?
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coupling between global dynamics and signal transduction pathways: a mechanism of allostery for chaperonin GroEL.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
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A Network of Conserved Interactions Regulates the Allosteric Signal in a Glutamine Amidotransferase†
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
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Allosteric cooperativity in protein kinase A.
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
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rRNA mutants in the yeast peptidyltransferase center reveal allosteric information networks and mechanisms of drug resistance.
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
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Exchanging murine and human immunoglobulin constant chains affects the kinetics and thermodynamics of antigen binding and chimeric antibody autoreactivity
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
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Contact rearrangements form coupled networks from local motions in allosteric proteins
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
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Interesting structural and dynamical behaviors exhibited by the AF-6 PDZ domain upon Bcr peptide binding.
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
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A conformational switch in the ligand-binding domain regulates the dependence of the glucocorticoid receptor on Hsp90.
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
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Evidence for a functional role of the dynamics of glycine-121 of Escherichia coli dihydrofolate reductase obtained from kinetic analysis of a site-directed mutant
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
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Structural identification of the pathway of long-range communication in an allosteric enzyme
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
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Dihydroorotase from Escherichia coli: loop movement and cooperativity between subunits.
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamic Allostery in the Ring Protein TRAP
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
IIAGlc inhibition of glycerol kinase: a communications network tunes protein motions at the allosteric site
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
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Principles underlying energetic coupling along an allosteric communication trajectory of a voltage-activated K+ channel
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
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Cooperative interactions between R531 and acidic residues in the voltage sensing module of hERG1 channels
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
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Signal transduction pathway of TonB-dependent transporters
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
Allosteric determinants in guanine nucleotide-binding proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
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Evolutionarily conserved pathways of energetic connectivity in protein families
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural determinants of allosteric ligand activation in RXR heterodimers.
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
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Reassessing a sparse energetic network within a single protein domain
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stated in
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metal import through microbial membranes
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamically driven protein allostery.
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
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Insulin allosteric behavior: detection, identification, and quantification of allosteric states via 19F NMR.
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
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A mutation in the S-switch region of the Runt domain alters the dynamics of an allosteric network responsible for CBFbeta regulation
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
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inferred from DOI database lookup
Definition of an electrostatic relay switch critical for the cAMP-dependent activation of protein kinase A as revealed by the D170A mutant of RIalpha
1 reference
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7 January 2021
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Using molecular dynamics to map interaction networks in an aminoacyl-tRNA synthetase.
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
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Propagation of Dynamic Changes in Barnase Upon Binding of Barstar: An NMR and Computational Study
1 reference
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7 January 2021
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Caspase inhibition, specifically
1 reference
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7 January 2021
based on heuristic
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Inhibition of caspase-2 by a designed ankyrin repeat protein: specificity, structure, and inhibition mechanism
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
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Allosteric modulation of nicotinic acetylcholine receptors
1 reference
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7 January 2021
based on heuristic
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Allosteric approaches to the targeting of G-protein-coupled receptors for novel drug discovery: a critical assessment
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
Allosterism and cannabinoid CB(1) receptors: the shape of things to come
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
Networks for the allosteric control of protein kinases
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
Searching for new allosteric sites in enzymes
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
Allosteric effects in the marginally stable von Hippel-Lindau tumor suppressor protein and allostery-based rescue mutant design
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
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Tethering: fragment-based drug discovery
1 reference
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7 January 2021
based on heuristic
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Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site
1 reference
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7 January 2021
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The design and synthesis of novel alpha-ketoamide-based p38 MAP kinase inhibitors
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Site-specific incorporation of allosteric-inhibition sites in a protein tyrosine phosphatase
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engineering allosteric protein switches by domain insertion
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
Engineering synthetic signaling proteins with ultrasensitive input/output control
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reprogramming control of an allosteric signaling switch through modular recombination
1 reference
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https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
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A molecular switch created by in vitro recombination of nonhomologous genes.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structure networks of E. coli glutaminyl-tRNA synthetase: effects of ligand binding.
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
inferred from DOI database lookup
A Three-Dimensional Model of the Myoglobin Molecule Obtained by X-Ray Analysis
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beginnings of feedback inhibition, allostery, and multi-protein complexes
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
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Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
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7 January 2021
based on heuristic
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Spin glasses and the statistical mechanics of protein folding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO.98
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NCHEMBIO.98
1 reference
stated in
Europe PubMed Central
PubMed ID
18641628
retrieved
21 June 2017
PubMed ID
18641628
1 reference
stated in
Europe PubMed Central
PubMed ID
18641628
retrieved
21 June 2017
ResearchGate publication ID
51415711
0 references
Springer Nature article ID
10.1038/nchembio.98
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