(Q30403036)

11 August 2017

Chemotherapy induces Notch1-dependent MRP1 up-regulation, inhibition of which sensitizes breast cancer cells to chemotherapy (English)

1 reference

11 August 2017

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3

Andrew M Hanby

1 reference

11 August 2017

Bethany J Williams

10

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James L Thorne

object named as

James L Thorne

11

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Thomas A Hughes

object named as

Thomas A Hughes

12

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author name string

Baek Kim

1

1 reference

11 August 2017

Sam L Stephen

2

1 reference

11 August 2017

Kieran Horgan

4

1 reference

11 August 2017

Sarah L Perry

5

1 reference

11 August 2017

Julie Richardson

6

1 reference

11 August 2017

Elizabeth A Roundhill

7

1 reference

11 August 2017

Elizabeth M A Valleley

8

1 reference

11 August 2017

Eldo T Verghese

9

1 reference

11 August 2017

language of work or name

English

0 references

publication date

11 September 2015

1 reference

full work available at URL

11 August 2017

http://eprints.whiterose.ac.uk/89230/

content deliverer

White Rose Research Online

object has role

published version

copyright license

Creative Commons Attribution 4.0 International

0 references

https://doi.org/10.1186/s12885-015-1625-y

copyright license

Creative Commons Attribution 4.0 International

0 references

1 reference

11 August 2017

15

1 reference

11 August 2017

634

1 reference

describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4567818/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Neoadjuvant chemotherapy induces expression levels of breast cancer resistance protein that predict disease-free survival in breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Notch inhibitors for cancer treatment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Combining Notch inhibition with current therapies for breast cancer treatment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Modulators of γ-secretase activity can facilitate the toxic side-effects and pathogenesis of Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

A phase II study of RO4929097 in metastatic colorectal cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Adjuvant tamoxifen reduces subsequent breast cancer in women with estrogen receptor-positive ductal carcinoma in situ: a study based on NSABP protocol B-24.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Gene expression, molecular class changes, and pathway analysis after neoadjuvant systemic therapy for breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Interacting with γ-secretase for treating Alzheimer's disease: from inhibition to modulation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Notch: Implications of endogenous inhibitors for therapy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Therapeutic potential of gamma-secretase inhibitors and modulators

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Role of the MRP1/ABCC1 multidrug transporter protein in cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Mammary stem cells and breast cancer--role of Notch signalling.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Cell and molecular biology of Notch.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Notch, Myc and breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Aberrant activation of notch signaling in human breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Notch in mammary gland development and breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Discrepancy between consensus recommendations and actual community use of adjuvant chemotherapy in women with breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Cancer multidrug resistance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

MRP1 not MDR1 gene expression is the predominant mechanism of acquired multidrug resistance in two prostate carcinoma cell lines.

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12885-015-1625-Y

NOTCH1 signaling promotes chemoresistance via regulating ABCC1 expression in prostate cancer stem cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12885-015-1625-Y

C-terminal Fragment of Presenilin Is the Molecular Target of a Dipeptidic γ-Secretase-specific Inhibitor DAPT (N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycinet-Butyl Ester)

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12885-015-1625-Y

The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567818

Expression of MRP1, LRP and Pgp in breast carcinoma patients treated with preoperative chemotherapy

26 November 2018

1 reference

12 December 2020

Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors

1 reference

12 December 2020

Breast cancer outcomes by steroid hormone receptor status assessed visually and by computer image analysis

1 reference

12 December 2020

Simultaneous activity of MRP1 and Pgp is correlated with in vitro resistance to daunorubicin and with in vivo resistance in adult acute myeloid leukemia

1 reference

12 December 2020

Multidrug resistance protein in recurrent breast cancer

1 reference

12 December 2020

Association of expression of MRP1, BCRP, LRP and ERCC1 with outcome of patients with locally advanced non-small cell lung cancer who received neoadjuvant chemotherapy

1 reference

12 December 2020

10.1186/S12885-015-1625-Y

Identifiers

DOI

1 reference

10.1186/S12885-015-1625-Y

11 August 2017

0 references

CORE ID

81916999

0 references

Dimensions Publication ID

0 references

1 reference

11 August 2017

PubMed publication ID

26362310

1 reference