(Q30409627)

20 August 2017

Kinetic isotope effects support the twisted amide mechanism of Pin1 peptidyl-prolyl isomerase (English)

1 reference

20 August 2017

Felicia A Etzkorn

8

0 references

author name string

Ana Y Mercedes-Camacho

1

1 reference

20 August 2017

Ashley B Mullins

2

1 reference

20 August 2017

Matthew D Mason

3

1 reference

20 August 2017

Guoyan G Xu

4

1 reference

20 August 2017

Brendan J Mahoney

5

1 reference

20 August 2017

Xingsheng Wang

6

1 reference

20 August 2017

Jeffrey W Peng

7

1 reference

20 August 2017

language of work or name

English

0 references

publication date

24 October 2013

1 reference

20 August 2017

1 reference

20 August 2017

52

1 reference

20 August 2017

44

1 reference

20 August 2017

7707-7713

1 reference

Cyclohexyl ketone inhibitors of Pin1 dock in a trans-diaxial cyclohexane conformation

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

A Reduced-Amide Inhibitor of Pin1 Binds in a Conformation Resembling a Twisted-Amide Transition State

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Complete determination of the Pin1 catalytic domain thermodynamic cycle by NMR lineshape analysis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

An evaluation of peptide-bond isosteres

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Convergent synthesis of alpha-ketoamide inhibitors of Pin1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Structural Basis for High-Affinity Peptide Inhibition of Human Pin1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Functionally important residues in the peptidyl-prolyl isomerase Pin1 revealed by unigenic evolution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Conformationally locked isostere of phosphoSer-cis-Pro inhibits Pin1 23-fold better than phosphoSer-trans-Pro isostere

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Structural insights into the catalytic mechanism of cyclophilin A

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

A human peptidyl-prolyl isomerase essential for regulation of mitosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Determination of enzymatic catalysis for the cis-trans-isomerization of peptide binding in proline-containing peptides

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Mutarotase equilibrium exchange kinetics studied by 13C-NMR.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Inhibition of FKBP rotamase activity by immunosuppressant FK506: twisted amide surrogate.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

PPIase catalysis by human FK506-binding protein proceeds through a conformational twist mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

6 Statistical analysis of enzyme kinetic data

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Proton magnetic resonance studies of carbonic anhydrase. II. Group controlling catalytic activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

How does Pin1 catalyze the cis-trans prolyl peptide bond isomerization? A QM/MM and mean reaction force study.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Theoretical and experimental investigation of the energetics of cis-trans proline isomerization in peptide models

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

The mechanism of cis-trans isomerization of prolyl peptides by cyclophilin

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

The solid-phase synthesis of side-chain-phosphorylated peptide-4-nitroanilides

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891376

Mechanistic studies of peptidyl prolyl cis-trans isomerase: evidence for catalysis by distortion

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24116866

12 December 2020

inferred from PubMed ID database lookup

The X-ray structure of a tetrapeptide bound to the active site of human cyclophilin A

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24116866

12 December 2020

inferred from PubMed ID database lookup

A mechanism for rotamase catalysis by the FK506 binding protein (FKBP)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24116866

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1021/BI400700B

1 reference

release_ptqlrnrzlvaefoqhcsyg6mgbly

20 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ptqlrnrzlvaefoqhcsyg6mgbly

24 November 2022

mapped directly with Wikidata item

1 reference

20 August 2017

PubMed publication ID

24116866

1 reference