(Q30413069)

English

Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export

scientific article

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scholarly article

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Europe PubMed Central

13 September 2017

Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export (English)

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Europe PubMed Central

13 September 2017

4

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12 June 2020

author name string

Matthew William Woods

1

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12 June 2020

Jessica Gayle Tong

2

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12 June 2020

Sean Kevin Tom

3

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12 June 2020

Peter Craig Cavanagh

5

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12 June 2020

Jimmy Dimitrios Dikeakos

6

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12 June 2020

S M Mansour Haeryfar

7

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12 June 2020

Stephen Dominic Barr

8

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12 June 2020

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publication date

3 April 2014

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13 September 2017

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12 June 2020

11

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12 June 2020

27

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12 June 2020

https://scigraph.springernature.com/pub.10.1186/1742-4690-11-27

0 references

Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Evolutionary conflicts between viruses and restriction factors shape immunity

1 reference

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20 June 2018

Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Mechanism, specificity and structure of the deubiquitinases

1 reference

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20 June 2018

Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells

1 reference

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20 June 2018

The ISG15 conjugation system broadly targets newly synthesized proteins: implications for the antiviral function of ISG15.

1 reference

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20 June 2018

Herc5 attenuates influenza A virus by catalyzing ISGylation of viral NS1 protein

1 reference

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20 June 2018

Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification

1 reference

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20 June 2018

Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein

1 reference

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20 June 2018

Antiviral response dictated by choreographed cascade of transcription factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Paleovirology--modern consequences of ancient viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Species specificity of the NS1 protein of influenza B virus: NS1 binds only human and non-human primate ubiquitin-like ISG15 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains.

1 reference

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20 June 2018

Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome

1 reference

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20 June 2018

Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

High efficiency of HIV-1 genomic RNA packaging and heterozygote formation revealed by single virion analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Deconvolution of blood microarray data identifies cellular activation patterns in systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

A census of human transcription factors: function, expression and evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Gene expression in primate liver during viral hemorrhagic fever

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Species-specific activity of HIV-1 Vpu and positive selection of tetherin transmembrane domain variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Vaccinia virus E3 protein prevents the antiviral action of ISG15

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Identification of interleukin-1 and interleukin-6-responsive genes in human monocyte-derived macrophages using microarrays.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

The RCC1 superfamily: from genes, to function, to disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Different roles for two ubiquitin-like domains of ISG15 in protein modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Host Gene Expression Profiling of Dengue Virus Infection in Cell Lines and Patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Selecton 2007: advanced models for detecting positive and purifying selection using a Bayesian inference approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

COBALT: constraint-based alignment tool for multiple protein sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Negative regulation of ISG15 E3 ligase EFP through its autoISGylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Herc5, an interferon-induced HECT E3 enzyme, is required for conjugation of ISG15 in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Natural selection on protein-coding genes in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Initial sequence of the chimpanzee genome and comparison with the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Selecton: a server for detecting evolutionary forces at a single amino-acid site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Requirement of phosphatidylinositol-4,5-bisphosphate for HERC1-mediated guanine nucleotide release from ARF proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Retroviral mRNA nuclear export elements regulate protein function and virion assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Nuclear RNA export

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

UBP43 (USP18) specifically removes ISG15 from conjugated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

A novel human gene encoding HECT domain and RCC1-like repeats interacts with cyclins and is potentially regulated by the tumor suppressor proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV-1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

THE HIV-1 REV PROTEIN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

p24 antigen capture assay for quantification of human immunodeficiency virus using readily available inexpensive reagents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Localization of HIV-1 RNA in mammalian nuclei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Human immunodeficiency virus envelope V1 and V2 regions influence replication efficiency in macrophages by affecting virus spread

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Intragenic cis-acting art gene-responsive sequences of the human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Functional analysis of CAR, the target sequence for the Rev protein of HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

Macrophage-tropic human immunodeficiency virus isolates from different patients exhibit unusual V3 envelope sequence homogeneity in comparison with T-cell-tropic isolates: definition of critical amino acids involved in cell tropism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

20 June 2018

The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects.

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-11-27

21 January 2018

1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype.

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-11-27

21 January 2018

Gene expression analyses reveal molecular relationships among 20 regions of the human CNS.

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-11-27

21 January 2018

The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-11-27

21 January 2018

A Ran-independent pathway for export of spliced mRNA.

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-11-27

21 January 2018

Evolutionary trajectories of primate genes involved in HIV pathogenesis.

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-11-27

21 January 2018

HIV integration site selection: targeting in macrophages and the effects of different routes of viral entry.

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-11-27

21 January 2018

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-11-27

21 January 2018

RCC1-like repeat proteins: a pangenomic, structurally diverse new superfamily of beta-propeller domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

26 November 2018

Galectin-1-matured human monocyte-derived dendritic cells have enhanced migration through extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021598

26 November 2018

HERC5, a HECT E3 ubiquitin ligase tightly regulated in LPS activated endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24693865

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm

1 reference

https://pubmed.ncbi.nlm.nih.gov/24693865

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression alterations in activated human T-cells induced by modeled microgravity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24693865

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific plasma membrane protein phenotype of culture-amplified and native human bone marrow mesenchymal stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24693865

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-4690-11-27

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24693865%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24693865%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24693865%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

ResearchGate publication ID

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