(Q30413675)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23486469%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

title

A calcineurin docking motif (LXVP) in dynamin-related protein 1 contributes to mitochondrial fragmentation and ischemic neuronal injury (English)

1 reference

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25 February 2020

2

1 reference

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25 February 2020

Jon Houtman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23486469%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Stefan Strack

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23486469%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

author name string

Andrew M Slupe

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23486469%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Kyle H Flippo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23486469%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Mark A Lobas

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23486469%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

language of work or name

English

0 references

publication date

13 March 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23486469%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

25 February 2020

published in

1 reference

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25 February 2020

volume

288

1 reference

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25 February 2020

issue

17

1 reference

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25 February 2020

page(s)

12353-12365

1 reference

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describes a project that uses

25 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3636919/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors.

20 June 2018

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N-terminal phosphorylation of protein phosphatase 2A/Bβ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival.

20 June 2018

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Allosteric modulation of Drp1 mechanoenzyme assembly and mitochondrial fission by the variable domain

20 June 2018

1 reference

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Cell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative disease

20 June 2018

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PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics.

20 June 2018

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Effects of FK506 on Hippocampal CA1 Cells Following Transient Global Ischemia/Reperfusion in Wistar Rat.

20 June 2018

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Determinants for Substrate Specificity of Protein Phosphatase 2A.

20 June 2018

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Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

20 June 2018

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During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.

20 June 2018

1 reference

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Recognition of β-calcineurin by the domains of calmodulin: thermodynamic and structural evidence for distinct roles

20 June 2018

1 reference

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Interaction of calcineurin with substrates and targeting proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization

20 June 2018

1 reference

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Drp1 dephosphorylation in ATP depletion-induced mitochondrial injury and tubular cell apoptosis

20 June 2018

1 reference

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Cracking the phosphatase code: docking interactions determine substrate specificity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Differential cell death regulation between adult-unloaded and aged rat soleus muscle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Functional characterization of phosphorylation sites in dynamin-related protein 1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Stimulation of glutamate receptors in cultured hippocampal neurons causes Ca2+-dependent mitochondrial contraction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Domain architecture of the regulators of calcineurin (RCANs) and identification of a divergent RCAN in yeast

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Oxidative stress and energy crises in neuronal dysfunction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

The complex structure of calmodulin bound to a calcineurin peptide

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Cyclin-dependent kinase 5 phosphorylates serine 31 of tyrosine hydroxylase and regulates its stability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Ca(2+) homeostasis during mitochondrial fragmentation and perinuclear clustering induced by hFis1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Imaging kinase--AKAP79--phosphatase scaffold complexes at the plasma membrane in living cells using FRET microscopy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Calcineurin: form and function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

High level calcineurin activity predisposes neuronal cells to apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Comparison of the reaction progress of calcineurin with Mn2+ and Mg2+.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Association of protein kinase A and protein phosphatase 2B with a common anchoring protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Statistical quality control and routine data processing for radioimmunoassays and immunoradiometric assays

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology.

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Calcineurin and mitochondrial function in glutamate-induced neuronal cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Calcium- and metabolic state-dependent modulation of the voltage-dependent Kv2.1 channel regulates neuronal excitability in response to ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: dose dependency, therapeutic time window and long-term efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Tacrolimus, a Potential Neuroprotective Agent, Ameliorates Ischemic Brain Damage and Neurologic Deficits after Focal Cerebral Ischemia in Nonhuman Primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Therapeutic time window of tacrolimus (FK506) in a nonhuman primate stroke model: comparison with tissue plasminogen activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Calcium-dependent spontaneously reversible remodeling of brain mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Different pathways lead to mitochondrial fragmentation during apoptotic and excitotoxic cell death in primary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Excitotoxic calcium overload in a subpopulation of mitochondria triggers delayed death in hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Dynamic changes of mitochondrial fusion and fission proteins after transient cerebral ischemia in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Glutamate decreases mitochondrial size and movement in primary forebrain neurons.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Calcineurin inhibitors FK506 and SDZ ASM 981 alleviate the outcome of focal cerebral ischemic/reperfusion injury.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

N-methyl-D-aspartate receptor desensitisation is neuroprotective by inhibiting glutamate-induced apoptotic-like death.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636919

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

26 November 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.459677

Blockade of NFAT activation by the second calcineurin binding site

21 January 2018

1 reference

12 December 2020

Quantitative endoproteinase GluC footprinting of cooperative Ca2+ binding to calmodulin: proteolytic susceptibility of E31 and E87 indicates interdomain interactions

1 reference

12 December 2020

miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

1 reference

12 December 2020

Mitochondrial Dysfunction and Dendritic Beading during Neuronal Toxicity

1 reference

12 December 2020

Glutamate-induced neuron death requires mitochondrial calcium uptake

1 reference

12 December 2020

Dephosphorylation of cAMP-dependent protein kinase regulatory subunit (type II) by calmodulin-dependent protein phosphatase. Determinants of substrate specificity

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M113.459677

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23486469%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23486469%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

PubMed publication ID

23486469

1 reference