(Q30414441)

21 August 2017

2 references

27 November 2019

3 May 2021

Current perspectives on the use of intravenous recombinant tissue plasminogen activator (tPA) for treatment of acute ischemic stroke (English)

1 reference

tissue plasminogen activator

21 August 2017

1 reference

27 November 2019

1 reference

27 November 2019

1 reference

2 October 2019

2 references

27 November 2019

3 May 2021

1 reference

PubMed publication ID

1 reference

Michelle C Johansen

3

0 references

author name string

Sherita N Chapman

1

1 reference

21 August 2017

Prachi Mehndiratta

2

1 reference

21 August 2017

Timothy L McMurry

4

1 reference

21 August 2017

Karen C Johnston

5

1 reference

21 August 2017

Andrew M Southerland

6

1 reference

21 August 2017

language of work or name

English

0 references

publication date

24 February 2014

10 references

Vascular Health and Risk Management

21 August 2017

19 March 2019

22 March 2019

25 April 2019

17 June 2019

25 June 2019

28 September 2019

2 October 2019

27 November 2019

3 May 2021

10 references

21 August 2017

19 March 2019

22 March 2019

25 April 2019

17 June 2019

25 June 2019

28 September 2019

2 October 2019

27 November 2019

3 May 2021

10

1 reference

21 August 2017

75-87

1 reference

Creative Commons Attribution-NonCommercial

21 August 2017

9 references

19 March 2019

22 March 2019

25 April 2019

17 June 2019

25 June 2019

28 September 2019

2 October 2019

27 November 2019

3 May 2021

on focus list of Wikimedia project

ScienceSource

0 references

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Thrombolysis, stroke-unit admission and early rehabilitation in elderly patients

20 June 2018

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Number needed to treat to benefit and to harm for intravenous tissue plasminogen activator therapy in the 3- to 4.5-hour window: joint outcome table analysis of the ECASS 3 trial

20 June 2018

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Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusion-diffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, double-blind, placebo-controlled study.

20 June 2018

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The HAT Score: a simple grading scale for predicting hemorrhage after thrombolysis

20 June 2018

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Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST).

20 June 2018

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20 June 2018

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Intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: an update

20 June 2018

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20 June 2018

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Intravenous thrombolysis in stroke patients of > or = 80 versus < 80 years of age--a systematic review across cohort studies.

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Classification and pathogenesis of cerebral hemorrhages after thrombolysis in ischemic stroke

20 June 2018

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20 June 2018

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Intravenous rt-PA for acute stroke: comparing its effectiveness in younger and older patients

20 June 2018

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Survey of emergency physicians about recombinant tissue plasminogen activator for acute ischemic stroke

20 June 2018

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Thrombolysis for acute ischemic stroke: results of the Canadian Alteplase for Stroke Effectiveness Study

20 June 2018

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Predicting major neurological improvement with intravenous recombinant tissue plasminogen activator treatment of stroke

20 June 2018

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Quality improvement and tissue-type plasminogen activator for acute ischemic stroke: a Cleveland update

20 June 2018

1 reference

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Thrombolytic therapy within 3 to 6 hours after onset of ischemic stroke: useful or harmful?

20 June 2018

1 reference

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Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: the Multicenter rt-PA Stroke Survey

20 June 2018

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Intravenous tissue-type plasminogen activator therapy for ischemic stroke: Houston experience 1996 to 2000.

20 June 2018

1 reference

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Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II)

20 June 2018

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Use of tissue-type plasminogen activator for acute ischemic stroke: the Cleveland area experience

20 June 2018

1 reference

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Thrombolysis in acute ischemic stroke: controlled trials and clinical experience

20 June 2018

1 reference

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Dichotomized efficacy end points and global end-point analysis applied to the ECASS intention-to-treat data set: post hoc analysis of ECASS I.

20 June 2018

1 reference

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Intravenous tissue plasminogen activator for acute ischemic stroke: feasibility, safety, and efficacy in the first year of clinical practice

20 June 2018

1 reference

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Epidemiology of Stroke in Innherred, Norway, 1994 to 1996 : Incidence and 30-Day Case-Fatality Rate

20 June 2018

1 reference

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Myths regarding the NINDS rt-PA Stroke Trial: setting the record straight.

20 June 2018

1 reference

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Diagnosis of cerebral amyloid angiopathy. Sensitivity and specificity of cortical biopsy.

20 June 2018

1 reference

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Variables associated with hospital arrival time after stroke: effect of delay on the clinical efficiency of early treatment

20 June 2018

1 reference

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Thrombolytic therapy in acute ischemic stroke

20 June 2018

1 reference

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Clinical features and pathogenesis of intracerebral hemorrhage after rt-PA and heparin therapy for acute myocardial infarction: the Thrombolysis in Myocardial Infarction (TIMI) II Pilot and Randomized Clinical Trial combined experience

20 June 2018

1 reference

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Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)

20 June 2018

1 reference

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MAST-I: agreeing to disagree. Multicentre Acute Stroke Trial--Italy Group

20 June 2018

1 reference

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Conditions that mimic stroke in the emergency department. Implications for acute stroke trials

20 June 2018

1 reference

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Tissue plasminogen activator for acute ischemic stroke

20 June 2018

1 reference

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Thrombolytic agents in the treatment of stroke

20 June 2018

1 reference

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Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke

20 June 2018

1 reference

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Urgent therapy for stroke. Part II. Pilot study of tissue plasminogen activator administered 91-180 minutes from onset

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Urgent therapy for stroke. Part I. Pilot study of tissue plasminogen activator administered within 90 minutes

20 June 2018

1 reference

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Intravenous recombinant tissue plasminogen activator in acute carotid artery territory stroke

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

The complexities of acute stroke decision-making: a survey of neurologists

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic stroke

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Tissue-type plasminogen activator for stroke mimics: continuing to be swift rather than delaying treatment to be sure

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Safety of thrombolysis in stroke mimics: results from a multicenter cohort study.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Clinical Policy: Use of intravenous tPA for the management of acute ischemic stroke in the emergency department.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Risk score for intracranial hemorrhage in patients with acute ischemic stroke treated with intravenous tissue-type plasminogen activator

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Telestroke ambulances in prehospital stroke management: concept and pilot feasibility study.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

An integer-based score to predict functional outcome in acute ischemic stroke: the ASTRAL score.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Reducing in-hospital delay to 20 minutes in stroke thrombolysis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Predicting the risk of symptomatic intracerebral hemorrhage in ischemic stroke treated with intravenous alteplase: safe Implementation of Treatments in Stroke (SITS) symptomatic intracerebral hemorrhage risk score

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

The iScore Predicts Effectiveness of Thrombolytic Therapy for Acute Ischemic Stroke

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

A multicentre, randomized, double-blinded, placebo-controlled Phase III study to investigate EXtending the time for Thrombolysis in Emergency Neurological Deficits (EXTEND).

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Outcomes in mild or rapidly improving stroke not treated with intravenous recombinant tissue-type plasminogen activator: findings from Get With The Guidelines-Stroke.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Improving door-to-needle times in acute ischemic stroke: the design and rationale for the American Heart Association/American Stroke Association's Target: Stroke initiative

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Safety and outcomes of intravenous thrombolysis in stroke mimics: a 6-year, single-care center study and a pooled analysis of reported series.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Timeliness of tissue-type plasminogen activator therapy in acute ischemic stroke: patient characteristics, hospital factors, and outcomes associated with door-to-needle times within 60 minutes

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Off-label thrombolysis is not associated with poor outcome in patients with stroke

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Very mild stroke patients benefit from intravenous tissue plasminogen activator without increase of intracranial hemorrhage

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Thrombolysis in stroke mimics: frequency, clinical characteristics, and outcome.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Safety and outcome after thrombolysis in stroke patients with mild symptoms

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

A risk score to predict intracranial hemorrhage after recombinant tissue plasminogen activator for acute ischemic stroke

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Empirical characteristics of litigation involving tissue plasminogen activator and ischemic stroke.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Outcome of stroke with mild or rapidly improving symptoms.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Frequency and predictors of symptomatic intracerebral hemorrhage in patients with ischemic stroke treated with recombinant tissue plasminogen activator outside clinical trials.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

The stroke-thrombolytic predictive instrument: a predictive instrument for intravenous thrombolysis in acute ischemic stroke.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Factors associated with in-hospital mortality after administration of thrombolysis in acute ischemic stroke patients: an analysis of the nationwide inpatient sample 1999 to 2002.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938499

Predictors of major neurologic improvement after thrombolysis in acute stroke

26 November 2018

1 reference

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Reasons for exclusion from thrombolytic therapy following acute ischemic stroke.

26 November 2018

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Utilization of intravenous tissue plasminogen activator for acute ischemic stroke

26 November 2018

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Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials

26 November 2018

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Eligibility for recombinant tissue plasminogen activator in acute ischemic stroke: a population-based study

26 November 2018

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Burden of first-ever ischemic stroke in the oldest old: evidence from a population-based study.

26 November 2018

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Misdiagnosis of stroke in tissue plasminogen activator-treated patients: characteristics and outcomes

26 November 2018

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Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke.

26 November 2018

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26 November 2018

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Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility.

26 November 2018

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Protocol violations in community-based rTPA stroke treatment are associated with symptomatic intracerebral hemorrhage.

26 November 2018

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Predictors of survival among elders suffering strokes in Taiwan: observation from a nationally representative sample

26 November 2018

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Serum glucose level and diabetes predict tissue plasminogen activator-related intracerebral hemorrhage in acute ischemic stroke.

26 November 2018

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26 November 2018

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Early intravenous thrombolysis for acute ischemic stroke in a community-based approach

26 November 2018

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Should thrombolytic therapy be the first-line treatment for acute ischemic stroke? Thrombolysis--not a panacea for ischemic stroke.

26 November 2018

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Streptokinase for acute ischemic stroke with relationship to time of administration: Australian Streptokinase (ASK) Trial Study Group.

26 November 2018

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Ascertaining the true incidence of stroke: experience from the Perth Community Stroke Study, 1989-1990.

26 November 2018

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26 November 2018

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Short- and long-term prognosis for very old stroke patients. The Copenhagen Stroke Study

26 November 2018

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12 December 2020

Views on the use of tissue plasminogen activator in acute ischemic stroke: a state-wide survey among neurologists and emergency medicine physicians in Indiana

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12 December 2020

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12 December 2020

The Desmoteplase in Acute Ischemic Stroke Trial (DIAS)

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12 December 2020

Prediction of outcome after ischemic stroke: the value of clinical scores

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12 December 2020

Generalized efficacy of t-PA for acute stroke. Subgroup analysis of the NINDS t-PA Stroke Trial

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12 December 2020

Feasibility and safety of intravenous thrombolysis for acute ischaemic stroke in northern Greece

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12 December 2020

Early stroke treatment associated with better outcome: the NINDS rt-PA stroke study

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12 December 2020

Deriving Number-Needed-to-Treat and Number-Needed-to-Harm From the Saint I Trial Results

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12 December 2020

Symptomatic ICH and outcomes in patients after IV tPA: a business of risk or risky business?

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12 December 2020

Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke

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12 December 2020

Early MRI and outcomes of untreated patients with mild or improving ischemic stroke

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12 December 2020

Practice advisory: thrombolytic therapy for acute ischemic stroke--summary statement. Report of the Quality Standards Subcommittee of the American Academy of Neurology

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12 December 2020

ATLANTIS trial: results for patients treated within 3 hours of stroke onset. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke

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12 December 2020

The rtPA (alteplase) 0- to 6-hour acute stroke trial, part A (A0276g) : results of a double-blind, placebo-controlled, multicenter study. Thromblytic therapy in acute ischemic stroke study investigators

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12 December 2020

Intravenous tissue-type plasminogen activator for treatment of acute stroke: the Standard Treatment with Alteplase to Reverse Stroke (STARS) study

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12 December 2020

Thrombolytic therapy in acute ischemic stroke

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12 December 2020

Should thrombolytic therapy be the first-line treatment for acute ischemic stroke?

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12 December 2020

Treatment of acute ischemic stroke. Challenging the concept of a rigid and universal time window

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12 December 2020

The clinical-DWI mismatch: a new diagnostic approach to the brain tissue at risk of infarction

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12 December 2020

Thrombolysis for acute stroke in routine clinical practice

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12 December 2020

Measurements of acute cerebral infarction: a clinical examination scale

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12 December 2020

Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial

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12 December 2020

Good outcomes in ischemic stroke patients treated with intravenous thrombolysis despite regressing neurological symptoms

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12 December 2020

Intravenous tissue plasminogen activator for acute ischemic stroke in patients aged 80 years and older : the tPA stroke survey experience

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12 December 2020

Identifiers

DOI

10.2147/VHRM.S39213

1 reference

21 August 2017

1 reference

21 August 2017

PubMed publication ID

24591838

1 reference