(Q30414821)

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A prospective, multicenter, phase I matched-comparison group trial of safety, pharmacokinetics, and preliminary efficacy of riluzole in patients with traumatic spinal cord injury

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

A prospective, multicenter, phase I matched-comparison group trial of safety, pharmacokinetics, and preliminary efficacy of riluzole in patients with traumatic spinal cord injury (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

phase I clinical trial

0 references

multicenter clinical trial

0 references

pharmacokinetics

1 reference

based on heuristic

inferred from title

Michael Fehlings

object named as

Michael G Fehlings

2

0 references

9

object named as

James S Harrop

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

author name string

Robert G Grossman

1

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Europe PubMed Central

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20 August 2017

Ralph F Frankowski

3

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Europe PubMed Central

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20 August 2017

Keith D Burau

4

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Europe PubMed Central

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20 August 2017

Diana S L Chow

5

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Europe PubMed Central

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20 August 2017

Charles Tator

6

1 reference

Europe PubMed Central

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20 August 2017

Angela Teng

7

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Europe PubMed Central

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20 August 2017

Elizabeth G Toups

8

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Europe PubMed Central

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20 August 2017

Bizhan Aarabi

10

1 reference

Europe PubMed Central

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20 August 2017

Christopher I Shaffrey

11

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Europe PubMed Central

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20 August 2017

Michele M Johnson

12

1 reference

Europe PubMed Central

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20 August 2017

Susan J Harkema

13

1 reference

Europe PubMed Central

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20 August 2017

Maxwell Boakye

14

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Europe PubMed Central

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20 August 2017

James D Guest

15

1 reference

Europe PubMed Central

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20 August 2017

Jefferson R Wilson

16

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Europe PubMed Central

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20 August 2017

publication date

11 October 2013

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Europe PubMed Central

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20 August 2017

Journal of Neurotrauma

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Europe PubMed Central

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20 August 2017

31

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20 August 2017

3

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Europe PubMed Central

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20 August 2017

239-255

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Europe PubMed Central

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20 August 2017

Delayed post-injury administration of riluzole is neuroprotective in a preclinical rodent model of cervical spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Riluzole for acute traumatic spinal cord injury: a promising neuroprotective treatment strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Translational potential of preclinical trials of neuroprotection through pharmacotherapy for spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Riluzole for the treatment of acute traumatic spinal cord injury: rationale for and design of the NACTN Phase I clinical trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Reference for the 2011 revision of the International Standards for Neurological Classification of Spinal Cord Injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Spinal cord injury sequelae alter drug pharmacokinetics: an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

L-arginine reverses alterations in drug disposition induced by spinal cord injury by increasing hepatic blood flow.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Guidelines for the management of acute cervical spine and spinal cord injuries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Secondary injury mechanisms of spinal cord trauma: a novel therapeutic approach for the management of secondary pathophysiology with the sodium channel blocker riluzole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Evaluation of the neuroprotective effects of sodium channel blockers after spinal cord injury: improved behavioral and neuroanatomical recovery with riluzole.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Mechanisms of secondary injury to spinal cord axons in vitro: role of Na+, Na(+)-K(+)-ATPase, the Na(+)-H+ exchanger, and the Na(+)-Ca2+ exchanger.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Noninactivating, tetrodotoxin-sensitive Na+ conductance in rat optic nerve axons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

20 June 2018

Pharmacology of riluzole in acute spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

26 November 2018

Incidence and severity of acute complications after spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

26 November 2018

North American Clinical Trials Network for the Treatment of Spinal Cord Injury: goals and progress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

26 November 2018

Results of a phase II placebo-controlled randomized trial of minocycline in acute spinal cord injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

26 November 2018

Upper- and Lower-Extremity Motor Recovery After Traumatic Cervical Spinal Cord Injury: An Update From the National Spinal Cord Injury Database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

26 November 2018

Characterization of neurological recovery following traumatic sensorimotor complete thoracic spinal cord injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

26 November 2018

Extent of spontaneous motor recovery after traumatic cervical sensorimotor complete spinal cord injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

26 November 2018

Novel injury mechanism in anoxia and trauma of spinal cord white matter: glutamate release via reverse Na+-dependent glutamate transport.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

26 November 2018

SCIM--spinal cord independence measure: a new disability scale for patients with spinal cord lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

26 November 2018

Sodium channel blockade reduces hypoxic sodium loading and sodium-dependent calcium loading.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904533

26 November 2018

Dependence of hypoxic cellular calcium loading on Na(+)-Ca2+ exchange

1 reference

https://pubmed.ncbi.nlm.nih.gov/23859435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of methylprednisolone, naloxone, and spinal cord trauma on four liver enzymes: observations from NASCIS 2. National Acute Spinal Cord Injury Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23859435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II

1 reference

https://pubmed.ncbi.nlm.nih.gov/23859435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion in ASIA impairment scale during the first year after traumatic spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/23859435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1089/NEU.2013.2969

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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