(Q30416881)

12 August 2017

Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate (English)

1 reference

12 August 2017

Mithun Raje

2

0 references

Webster L Santos

object named as

Webster L Santos

7

0 references

author name string

Yugesh Kharel

1

1 reference

12 August 2017

Ming Gao

3

1 reference

12 August 2017

Amanda M Gellett

4

1 reference

12 August 2017

Jose L Tomsig

5

1 reference

12 August 2017

Kevin R Lynch

6

1 reference

12 August 2017

language of work or name

English

0 references

publication date

1 October 2012

1 reference

12 August 2017

1 reference

12 August 2017

447

1 reference

12 August 2017

1

1 reference

12 August 2017

149-157

1 reference

Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1.

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

A rapid assay for assessment of sphingosine kinase inhibitors and substrates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Antiestrogenic effects of the novel sphingosine kinase-2 inhibitor ABC294640

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Discovery of novel sphingosine kinase 1 inhibitors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Essential role for sphingosine kinases in neural and vascular development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Sphingolipid uptake by cultured cells: complex aggregates of cell sphingolipids with serum proteins and lipoproteins are rapidly catabolized.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Molecular cloning and functional characterization of murine sphingosine kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members

20 June 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120609

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120609

Experimental osteoarthritis in rats is attenuated by ABC294640, a selective inhibitor of sphingosine kinase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120609

Efficacy of a novel sphingosine kinase inhibitor in experimental Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120609

Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120609

Redistribution of sphingosine 1-phosphate by sphingosine kinase 2 contributes to lymphopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120609

Medicinal herbs: drugs or dietary supplements?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120609

Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443596

Specificity of inhibitors of serine palmitoyltransferase (SPT), a key enzyme in sphingolipid biosynthesis, in intact cells. A novel evaluation system using an SPT-defective mammalian cell mutant

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22747486

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The sphingosine kinase-sphingosine-1-phosphate axis is a determinant of mast cell function and anaphylaxis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22747486

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20120609

1 reference

release_hit2xyuwtbh2hojg3bnp24l5je

12 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hit2xyuwtbh2hojg3bnp24l5je

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

12 August 2017

PubMed publication ID

22747486

1 reference