(Q30422401)

10 August 2017

Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program (English)

1 reference

10 August 2017

1 reference

1 reference

Douglas Curran-Everett

Douglas Curran-Everett

8

0 references

Sean B Fain

Sean B Fain

10

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Eric A Hoffman

Eric A Hoffman

15

0 references

Kian Fan Chung

Kian Fan Chung

7

0 references

William W Busse

24

William W Busse

1 reference

10 August 2017

3

Eugene R Bleecker

1 reference

10 August 2017

23

Sally E Wenzel

1 reference

10 August 2017

16

Fernando Holguin

1 reference

10 August 2017

2

Serpil C Erzurum

1 reference

10 August 2017

22

W Gerald Teague

1 reference

10 August 2017

6

Suzy A A Comhair

1 reference

10 August 2017

1

Nizar N Jarjour

1 reference

10 August 2017

9

Raed A Dweik

1 reference

10 August 2017

14

Annette Hastie

1 reference

10 August 2017

17

Bruce D Levy

1 reference

10 August 2017

21

Ronald L Sorkness

1 reference

10 August 2017

12

Benjamin M Gaston

1 reference

10 August 2017

13

Elliot Israel

1 reference

10 August 2017

William J Calhoun

4

1 reference

10 August 2017

Mario Castro

5

1 reference

10 August 2017

Anne M Fitzpatrick

11

1 reference

10 August 2017

Deborah A Meyers

18

1 reference

10 August 2017

Wendy C Moore

19

1 reference

10 August 2017

Stephen P Peters

20

1 reference

10 August 2017

NHLBI Severe Asthma Research Program (SARP)

25

1 reference

10 August 2017

language of work or name

English

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publication date

17 November 2011

1 reference

American Journal of Respiratory and Critical Care Medicine

10 August 2017

1 reference

10 August 2017

185

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10 August 2017

4

1 reference

10 August 2017

356-362

1 reference

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Genomic differences distinguish the myofibroblast phenotype of distal lung fibroblasts from airway fibroblasts.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

The biochemistry of asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Lung imaging in asthmatic patients: the picture is clearer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Obesity and asthma: an association modified by age of asthma onset

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Detrimental effects of environmental tobacco smoke in relation to asthma severity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Safety of investigative bronchoscopy in the Severe Asthma Research Program

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Importance of hedgehog interacting protein and other lung function genes in asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Urinary bromotyrosine measures asthma control and predicts asthma exacerbations in children

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Sex dependence of airflow limitation and air trapping in children with severe asthma.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Progressive airflow limitation is a feature of children with severe asthma.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Vaccination of patients with mild and severe asthma with a 2009 pandemic H1N1 influenza virus vaccine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Racial differences in biologic predictors of severe asthma: Data from the Severe Asthma Research Program

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Glutathione oxidation is associated with airway macrophage functional impairment in children with severe asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

A large-scale, consortium-based genomewide association study of asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Predicting intermediate phenotypes in asthma using bronchoalveolar lavage-derived cytokines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Breath formate is a marker of airway S-nitrosothiol depletion in severe asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Corticosteroid suppression of lipoxin A4 and leukotriene B4 from alveolar macrophages in severe asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Noninvasive markers of airway inflammation in asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Genome-wide association study identifies five loci associated with lung function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Obesity, asthma, and oxidative stress

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Levels of nitric oxide oxidation products are increased in the epithelial lining fluid of children with persistent asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Effects of the menstrual cycle on lung function variables in women with asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Airway glutathione homeostasis is altered in children with severe asthma: evidence for oxidant stress

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

A multivariate analysis of risk factors for the air-trapping asthmatic phenotype as measured by quantitative CT analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Airway remodeling measured by multidetector CT is increased in severe asthma and correlates with pathology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Alterations of the arginine metabolome in asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Airway responsiveness in mild to moderate childhood asthma: sex influences on the natural history

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Alveolar macrophage phagocytosis is impaired in children with poorly controlled asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage-derived cytokines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

A chitinase-like protein in the lung and circulation of patients with severe asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Epithelial cell proliferation contributes to airway remodeling in severe asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

IL4R alpha mutations are associated with asthma exacerbations and mast cell/IgE expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Features of severe asthma in school-age children: Atopy and increased exhaled nitric oxide

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Airway nitric oxide release is reduced after PBS inhalation in asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Asthma: defining of the persistent adult phenotypes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Regional fibroblast heterogeneity in the lung: implications for remodeling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Investigative bronchoprovocation and bronchoscopy in airway diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Diminished lipoxin biosynthesis in severe asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Pathophysiology of severe asthma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Investigative use of bronchoscopy in asthma.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297096

Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation

20 June 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201107-1317PP

p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201107-1317PP

Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201107-1317PP

Cigarette smoking impairs the therapeutic response to oral corticosteroids in chronic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201107-1317PP

The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201107-1317PP

Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions. American Thoracic Society

21 January 2018

1 reference

12 December 2020

Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages

1 reference

12 December 2020

Summary and recommendations of a workshop on the investigative use of fiberoptic bronchoscopy and bronchoalveolar lavage in asthmatics

1 reference

12 December 2020

Guidelines for the diagnosis and management of asthma. National Heart, Lung, and Blood Institute. National Asthma Education Program. Expert Panel Report

1 reference

12 December 2020

Investigative use of bronchoscopy, lavage and bronchial biopsies in asthma and other airways diseases

1 reference

12 December 2020

10.1164/RCCM.201107-1317PP

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

22095547

1 reference