(Q30424110)

English

A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22883572%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22883572%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

2

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10 February 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22883572%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Josephine C. Adams

3

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10 February 2020

author name string

Asier Jayo

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13 August 2017

Josephine C Adams

3

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13 August 2017

publication date

10 August 2012

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10 February 2020

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10 February 2020

10

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10 February 2020

72

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10 February 2020

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0 references

Cofilin cooperates with fascin to disassemble filopodial actin filaments

1 reference

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The roles of fascins in health and disease

1 reference

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Reducing background fluorescence reveals adhesions in 3D matrices

1 reference

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Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis

1 reference

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LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells

1 reference

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Migrastatin analogues target fascin to block tumour metastasis

1 reference

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MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro

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The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488970

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LIMK1 and LIMK2 are important for metastatic behavior and tumor cell-induced angiogenesis of pancreatic cancer cells

1 reference

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The cofilin activity cycle in lamellipodia and invadopodia

1 reference

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Fascin regulates prostate cancer cell invasion and is associated with metastasis and biochemical failure in prostate cancer

1 reference

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Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion

1 reference

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Phosphorylation of myosin regulatory light chain by myosin light chain kinase, and muscle contraction

1 reference

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20 June 2018

ROCK1 and LIMK2 interact in spread but not blebbing cancer cells

1 reference

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20 June 2018

Rac regulates the interaction of fascin with protein kinase C in cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488970

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Lifeact: a versatile marker to visualize F-actin

1 reference

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20 June 2018

Ins and outs of ADF/cofilin activity and regulation

1 reference

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20 June 2018

The actin cytoskeleton in cancer cell motility

1 reference

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20 June 2018

Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488970

20 June 2018

Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488970

20 June 2018

Quantification of integrin receptor agonism by fluorescence lifetime imaging

1 reference

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20 June 2018

Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488970

20 June 2018

Intrinsic dynamic behavior of fascin in filopodia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488970

20 June 2018

Fascin, a novel target of beta-catenin-TCF signaling, is expressed at the invasive front of human colon cancer

1 reference

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The cofilin pathway in breast cancer invasion and metastasis

1 reference

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Independent prognostic value of fascin immunoreactivity in stage III-IV colonic adenocarcinoma

1 reference

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LIM kinases: function, regulation and association with human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488970

20 June 2018

Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488970

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LIM kinase 2 is widely expressed in all tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488970

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Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration

1 reference

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Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker?

1 reference

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Multiphoton-FLIM quantification of the EGFP-mRFP1 FRET pair for localization of membrane receptor-kinase interactions

1 reference

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1 reference

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Pak-1 expression increases with progression of colorectal carcinomas to metastasis

1 reference

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1 reference

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Independent prognostic value of fascin immunoreactivity in stage I nonsmall cell lung cancer

1 reference

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Tenascin-C suppresses Rho activation

1 reference

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1 reference

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Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

1 reference

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Cell-matrix adhesions differentially regulate fascin phosphorylation

1 reference

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1 reference

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1 reference

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1 reference

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Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

1 reference

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1 reference

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Cell-adhesive responses to tenascin-C splice variants involve formation of fascin microspikes

1 reference

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Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin

1 reference

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1 reference

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1 reference

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1 reference

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Cloning and expression of a murine fascin homolog from mouse brain

1 reference

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1 reference

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1 reference

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1 reference

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Purification and characterization of an F-actin-bundling 55-kilodalton protein from HeLa cells

1 reference

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Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin

1 reference

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Separation and interaction of the major components of sea urchin actin gel

1 reference

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LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics

1 reference

https://api.crossref.org/works/10.1186%2F1741-7007-10-72

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Initiation of cofilin activity in response to EGF is uncoupled from cofilin phosphorylation and dephosphorylation in carcinoma cells

1 reference

https://api.crossref.org/works/10.1186%2F1741-7007-10-72

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1 reference

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26 November 2018

Identifiers

10.1186/1741-7007-10-72

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22883572%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22883572%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22883572%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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