(Q30425161)

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Delivery of large heterologous polypeptides across the cytoplasmic membrane of antigen-presenting cells by the Bordetella RTX hemolysin moiety lacking the adenylyl cyclase domain

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scholarly article

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Europe PubMed Central

PMC publication ID

10 August 2017

Delivery of large heterologous polypeptides across the cytoplasmic membrane of antigen-presenting cells by the Bordetella RTX hemolysin moiety lacking the adenylyl cyclase domain (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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infectious disease

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based on heuristic

inferred from title

2

object named as

Jana Kamanova

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Europe PubMed Central

PMC publication ID

10 August 2017

object named as

Peter Sebo

11

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author name string

Jana Holubova

1

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Europe PubMed Central

PMC publication ID

10 August 2017

Jiri Jelinek

3

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Europe PubMed Central

PMC publication ID

10 August 2017

Jakub Tomala

4

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Europe PubMed Central

PMC publication ID

10 August 2017

Jiri Masin

5

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Europe PubMed Central

PMC publication ID

10 August 2017

Martina Kosova

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Ondrej Stanek

7

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Europe PubMed Central

PMC publication ID

10 August 2017

Ladislav Bumba

8

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Europe PubMed Central

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10 August 2017

Jaroslav Michalek

9

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Europe PubMed Central

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10 August 2017

Marek Kovar

10

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10 August 2017

language of work or name

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publication date

3 January 2012

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Europe PubMed Central

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10 August 2017

Infection and Immunity

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Europe PubMed Central

PMC publication ID

10 August 2017

80

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Europe PubMed Central

PMC publication ID

10 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1181-1192

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

RTX proteins: a highly diverse family secreted by a common mechanism

1 reference

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14 July 2018

Bordetella adenylate cyclase toxin mobilizes its beta2 integrin receptor into lipid rafts to accomplish translocation across target cell membrane in two steps

1 reference

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Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors

1 reference

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Design and pre-clinical evaluation of a universal HIV-1 vaccine

1 reference

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CMV pp65 and IE-1 T cell epitopes recognized by healthy subjects

1 reference

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14 July 2018

Third activity of Bordetella adenylate cyclase (AC) toxin-hemolysin. Membrane translocation of AC domain polypeptide promotes calcium influx into CD11b+ monocytes independently of the catalytic and hemolytic activities

1 reference

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High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection

1 reference

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Immunization with a circumsporozoite epitope fused to Bordetella pertussis adenylate cyclase in conjunction with cytotoxic T-lymphocyte-associated antigen 4 blockade confers protection against Plasmodium berghei liver-stage malaria

1 reference

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14 July 2018

Pore-forming and enzymatic activities of Bordetella pertussis adenylate cyclase toxin synergize in promoting lysis of monocytes

1 reference

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An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis

1 reference

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Bordetella adenylate cyclase toxin: a swift saboteur of host defense

1 reference

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14 July 2018

Macrophage cytotoxicity produced by adenylate cyclase toxin from Bordetella pertussis: more than just making cyclic AMP!

1 reference

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14 July 2018

Acylation of lysine 860 allows tight binding and cytotoxicity of Bordetella adenylate cyclase on CD11b-expressing cells

1 reference

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14 July 2018

Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin

1 reference

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14 July 2018

The adenylate cyclase toxin from Bordetella pertussis--a novel promising vehicle for antigen delivery to dendritic cells

1 reference

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14 July 2018

Interaction of Bordetella pertussis adenylate cyclase with CD11b/CD18: Role of toxin acylation and identification of the main integrin interaction domain

1 reference

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14 July 2018

Delivery of multiple epitopes by recombinant detoxified adenylate cyclase of Bordetella pertussis induces protective antiviral immunity

1 reference

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14 July 2018

The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18)

1 reference

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14 July 2018

Penetration of protein toxins into cells

1 reference

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14 July 2018

An amphipathic alpha-helix including glutamates 509 and 516 is crucial for membrane translocation of adenylate cyclase toxin and modulates formation and cation selectivity of its membrane channels

1 reference

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14 July 2018

Delivery of CD8(+) T-cell epitopes into major histocompatibility complex class I antigen presentation pathway by Bordetella pertussis adenylate cyclase: delineation of cell invasive structures and permissive insertion sites

1 reference

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14 July 2018

Epitope mapping of monoclonal antibodies against Bordetella pertussis adenylate cyclase toxin

1 reference

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14 July 2018

Delivery of protein to the cytosol of macrophages using Escherichia coli K-12.

1 reference

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14 July 2018

Direct delivery of the Bordetella pertussis adenylate cyclase toxin to the MHC class I antigen presentation pathway.

1 reference

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14 July 2018

Anti-viral protection conferred by recombinant adenylate cyclase toxins from Bordetella pertussis carrying a CD8+ T cell epitope from lymphocytic choriomeningitis virus

1 reference

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Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules

1 reference

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The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL.

1 reference

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Adenylate cyclase toxin from Bordetella pertussis produces ion conductance across artificial lipid bilayers in a calcium- and polarity-dependent manner

1 reference

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14 July 2018

Internal lysine palmitoylation in adenylate cyclase toxin from Bordetella pertussis

1 reference

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14 July 2018

Membrane depolarization prevents cell invasion by Bordetella pertussis adenylate cyclase toxin

1 reference

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Hemolytic, but not cell-invasive activity, of adenylate cyclase toxin is selectively affected by differential fatty-acylation in Escherichia coli

1 reference

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Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin

1 reference

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Adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. Different processes for interaction with and entry into target cells

1 reference

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1 reference

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Adenylate cyclase toxin from Bordetella pertussis. Conformational change associated with toxin activity

1 reference

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1 reference

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1 reference

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Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis

1 reference

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Adenylate cyclase toxin translocates across target cell membrane without forming a pore

1 reference

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Oligomerization is involved in pore formation by Bordetella adenylate cyclase toxin.

1 reference

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Adenylate cyclase toxin (CyaA) of Bordetella pertussis. Evidence for the formation of small ion-permeable channels and comparison with HlyA of Escherichia coli.

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Distinct steps in the penetration of adenylate cyclase toxin of Bordetella pertussis into sheep erythrocytes. Translocation of the toxin across the membrane

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Segments Crucial for Membrane Translocation and Pore-forming Activity ofBordetellaAdenylate Cyclase Toxin

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Interaction of Bordetella pertussis adenylate cyclase with calmodulin. Identification of two separated calmodulin-binding domains

1 reference

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12 December 2020

based on heuristic

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Interaction of Calcium withBordetella pertussisAdenylate Cyclase Toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22215742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapy of murine tumors with recombinant Bordetella pertussis adenylate cyclase carrying a cytotoxic T cell epitope

1 reference

https://pubmed.ncbi.nlm.nih.gov/22215742

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Dendritic cell vaccination in allogeneic stem cell recipients: induction of human cytomegalovirus (HCMV)-specific cytotoxic T lymphocyte responses even in patients receiving a transplant from an HCMV-seronegative donor

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Identifiers

10.1128/IAI.05711-11

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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