(Q30427044)

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Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

phosphorylation

1 reference

based on heuristic

inferred from title

rhabdomyosarcoma

1 reference

based on heuristic

inferred from title

cell differentiation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Lavinia Raimondi

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Federica Verginelli

4

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

12

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Stefano Stifani

13

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

14

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Europe PubMed Central

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17 January 2020

16

1 reference

Europe PubMed Central

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17 January 2020

author name string

R Ciarapica

2

1 reference

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17 January 2020

M De Salvo

3

1 reference

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17 January 2020

M Gueguen

5

1 reference

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17 January 2020

C Martini

6

1 reference

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17 January 2020

L De Sio

7

1 reference

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17 January 2020

G Cortese

8

1 reference

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17 January 2020

M Locatelli

9

1 reference

Europe PubMed Central

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17 January 2020

T P Dang

10

1 reference

Europe PubMed Central

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17 January 2020

N Carlesso

11

1 reference

Europe PubMed Central

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17 January 2020

F Locatelli

15

1 reference

Europe PubMed Central

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17 January 2020

publication date

25 November 2011

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Cell Death & Differentiation

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

19

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

871-881

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Notch signaling: simplicity in design, versatility in function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Notch signalling in solid tumours: a little bit of everything but not all the time

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Notch pathway inhibition significantly reduces rhabdomyosarcoma invasiveness and mobility in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Therapeutic antibody targeting of individual Notch receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Targeting specific regions of the Notch3 ligand-binding domain induces apoptosis and inhibits tumor growth in lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Targeting Id protein interactions by an engineered HLH domain induces human neuroblastoma cell differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Defining the cooperative genetic changes that temporally drive alveolar rhabdomyosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Control of the reversibility of cellular quiescence by the transcriptional repressor HES1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Pediatric soft tissue sarcomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Tenets of PTEN tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Asymmetric self-renewal and commitment of satellite stem cells in muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Selective control of skeletal muscle differentiation by Akt1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Notch signaling suppresses p38 MAPK activity via induction of MKP-1 in myogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Notch2 negatively regulates myofibroblastic differentiation of myoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Inhibition of Notch signaling induces myotube hypertrophy by recruiting a subpopulation of reserve cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

p21WAF1 expression induced by MEK/ERK pathway activation or inhibition correlates with growth arrest, myogenic differentiation and onco-phenotype reversal in rhabdomyosarcoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Mammalian target of rapamycin (mTOR) signaling is required for a late-stage fusion process during skeletal myotube maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

The role of Notch in tumorigenesis: oncogene or tumour suppressor?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

HES and HERP families: multiple effectors of the Notch signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Notch signaling induces cell cycle arrest in small cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Notch signaling: cell fate control and signal integration in development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

20 June 2018

Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2011.171

21 January 2018

Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2011.171

21 January 2018

Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2011.171

21 January 2018

Notch: a membrane-bound transcription factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321627

26 November 2018

Notch-mediated restoration of regenerative potential to aged muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22117196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22117196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Notch3 and IL-1beta exert opposing effects on a vascular smooth muscle cell inflammatory pathway in which NF-kappaB drives crosstalk

1 reference

https://pubmed.ncbi.nlm.nih.gov/22117196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Notch3 null mutation in mice causes muscle hyperplasia by repetitive muscle regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22117196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/CDD.2011.171

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117196%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

ResearchGate publication ID

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