(Q30427556)

English

Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus

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scholarly article

1 reference

Europe PubMed Central

16 September 2017

Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus (English)

1 reference

Europe PubMed Central

16 September 2017

influenza A virus

object named as

influenza A virus

1 reference

based on heuristic

inferred from title

3

object named as

Jun Wang

1 reference

Europe PubMed Central

16 September 2017

William DeGrado

10

object named as

William F DeGrado

1 reference

Europe PubMed Central

16 September 2017

Michael L. Klein

9

object named as

Michael L Klein

1 reference

Europe PubMed Central

16 September 2017

8

object named as

Robert A Lamb

1 reference

Europe PubMed Central

16 September 2017

6

object named as

Giacomo Fiorin

1 reference

Europe PubMed Central

16 September 2017

Lawrence H Pinto

7

object named as

Lawrence H Pinto

1 reference

Europe PubMed Central

16 September 2017

5

object named as

Belgin Canturk

1 reference

Europe PubMed Central

16 September 2017

author name string

Jizhou Wang

1

1 reference

Europe PubMed Central

16 September 2017

Chunlong Ma

2

1 reference

Europe PubMed Central

16 September 2017

Hyunil Jo

4

1 reference

Europe PubMed Central

16 September 2017

language of work or name

0 references

publication date

27 March 2013

1 reference

Europe PubMed Central

16 September 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

16 September 2017

56

1 reference

Europe PubMed Central

16 September 2017

7

1 reference

Europe PubMed Central

16 September 2017

2804-2812

1 reference

Europe PubMed Central

16 September 2017

Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Design and synthesis of pinanamine derivatives as anti-influenza A M2 ion channel inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Antivirals targeting influenza A virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Magic-angle-spinning NMR of the drug resistant S31N M2 proton transporter from influenza A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Structural investigation of rimantadine inhibition of the AM2-BM2 chimera channel of influenza viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Chloroquine for influenza prevention: a randomised, double-blind, placebo controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Evidence of person-to-person transmission of oseltamivir-resistant pandemic influenza A(H1N1) 2009 virus in a hematology unit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Dual resistance to adamantanes and oseltamivir among seasonal influenza A(H1N1) viruses: 2008-2010.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Emerging influenza antiviral resistance threats

1 reference

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20 June 2018

Discovery of highly potent agents against influenza A virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Insight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid Bilayer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Identification of hits as matrix-2 protein inhibitors through the focused screening of a small primary amine library

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Functional studies and modeling of pore-lining residue mutants of the influenza a virus M2 ion channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Solid-supported membrane technology for the investigation of the influenza A virus M2 channel activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Structure and function of the influenza A M2 proton channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Oseltamivir- and amantadine-resistant influenza viruses A (H1N1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Mechanism of drug inhibition and drug resistance of influenza A M2 channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Global transmission of oseltamivir-resistant influenza

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Structure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: The Role of Ser31 in Amantadine Binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

High-throughput screening of a 100,000-compound library for inhibitors of influenza A virus (H3N2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Surveillance for neuraminidase inhibitor resistance among human influenza A and B viruses circulating worldwide from 2004 to 2008.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Structural basis for the function and inhibition of an influenza virus proton channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Structure and mechanism of the M2 proton channel of influenza A virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

The oligomeric state of the active BM2 ion channel protein of influenza B virus

1 reference

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20 June 2018

Different pH requirements are associated with divergent inhibitory effects of chloroquine on human and avian influenza A viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Anti-influenza virus agents: synthesis and mode of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Antiviral agents active against influenza A viruses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

In vitro inhibition of human influenza A virus replication by chloroquine

1 reference

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20 June 2018

Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern

1 reference

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20 June 2018

Reductive amination of carbohydrates using NaBH(OAc)3.

1 reference

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20 June 2018

Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures(1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Growth impairment resulting from expression of influenza virus M2 protein in Saccharomyces cerevisiae: identification of a novel inhibitor of influenza virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

The molecular basis of the specific anti-influenza action of amantadine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Maturation of influenza A virus hemagglutinin--estimates of the pH encountered during transport and its regulation by the M2 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Influenza virus M2 protein has ion channel activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

20 June 2018

Emergence of oseltamivir-resistant pandemic H1N1 virus during prophylaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036227

26 November 2018

Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States

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26 November 2018

Redox behavior of ferrocene-containing rotaxane: transposition of the rotaxane wheel by redox reaction of a ferrocene moiety tethered at the end of the axle.

1 reference

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26 November 2018

Identifiers

10.1021/JM301538E

1 reference

Europe PubMed Central

16 September 2017

1 reference

Europe PubMed Central

16 September 2017

1 reference

Europe PubMed Central

16 September 2017

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