(Q30427638)

21 June 2017

title

The ZIC gene family encodes multi-functional proteins essential for patterning and morphogenesis (English)

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21 June 2017

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3

Sabine Tejpar

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author name string

Rob Houtmeyers

series ordinal

1

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21 June 2017

Jacob Souopgui

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2

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21 June 2017

Ruth Arkell

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4

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21 June 2017

publication date

27 February 2013

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Cellular and Molecular Life Sciences

21 June 2017

published in

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21 June 2017

volume

70

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21 June 2017

issue

20

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21 June 2017

page(s)

3791-3811

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A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells

21 June 2017

cites work

1 reference

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21 January 2018

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Xenopus Zic3, a primary regulator both in neural and neural crest development

21 January 2018

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Zebrafish zic1 expression in brain and somites is affected by BMP and hedgehog signalling

21 January 2018

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macho-1-Related genes in Ciona embryos

21 January 2018

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A wide-range phylogenetic analysis of Zic proteins: implications for correlations between protein structure conservation and body plan complexity.

21 January 2018

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Expression and phylogenetic analysis of the zic gene family in the evolution and development of metazoans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Transcription factor Zic2 inhibits Wnt/β-catenin protein signaling

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Identification of a novel ZIC3 isoform and mutation screening in patients with heterotaxy and congenital heart disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zinc fingers of the cerebellum (Zic): transcription factors and co-factors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic2 is required for neural crest formation and hindbrain patterning during mouse development.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

In vitro analysis of partial loss-of-function ZIC2 mutations in holoprosencephaly: alanine tract expansion modulates DNA binding and transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Characterization of the tandem CWCH2 sequence motif: a hallmark of inter-zinc finger interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Elucidation of penetrance variability of a ZIC3 mutation in a family with complex heart defects and functional analysis of ZIC3 mutations in the first zinc finger domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Myogenic repressor I-mfa interferes with the function of Zic family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Holoprosencephaly due to mutations in ZIC2: alanine tract expansion mutations may be caused by parental somatic recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Polyalanine expansion in the ZIC3 gene leading to X-linked heterotaxy with VACTERL association: a new polyalanine disorder?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Physical and functional interactions between Zic and Gli proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Insights into the evolutionary history of the vertebrate zic3 locus from a teleost-specific zic6 gene in the zebrafish, Danio rerio.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

The zebrafish zic2a-zic5 gene pair acts downstream of canonical Wnt signaling to control cell proliferation in the developing tectum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Emerging roles for zic genes in early development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

The ZIC gene family in development and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

The role of Zic genes in neural development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic2 is expressed in pluripotent cells in the blastocyst and adult brain expression overlaps with makers of neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

A new murine zinc finger gene, Opr.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic4, a zinc-finger transcription factor, is expressed in the developing mouse nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

The role of Zic family zinc finger transcription factors in the proliferation and differentiation of retinal progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Sequence relationships and expression patterns of zebrafish zic2 and zic5 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Disruption of gradient expression of Zic3 resulted in abnormal intra-retinal axon projection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Xenopus Zic4: conservation and diversification of expression profiles and protein function among the Xenopus Zic family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

A novel member of the Xenopus Zic family, Zic5, mediates neural crest development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Xenopus Zic family and its role in neural and neural crest development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic3 is critical for early embryonic patterning during gastrulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

An essential and highly conserved role for Zic3 in left-right patterning, gastrulation and convergent extension morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Heart defects in X-linked heterotaxy: evidence for a genetic interaction of Zic3 with the nodal signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Initiating head development in mouse embryos: integrating signalling and transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

The full spectrum of holoprosencephaly-associated mutations within the ZIC2 gene in humans predicts loss-of-function as the predominant disease mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Phenotype of the neural tube defect mouse model bent tail is not sensitive to maternal folinic acid, myo-inositol, or zinc supplementation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

The X-linked mouse mutation Bent tail is associated with a deletion of the Zic3 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Further characterization of the genetic defect of the Bent tail mouse, a mouse model for human neural tube defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Characterization of Opr deficiency in mouse brain: subtle defects in dorsomedial telencephalon and medioventral forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic2 regulates the kinetics of neurulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Central roles of the roof plate in telencephalic development and holoprosencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic2 and Zic3 synergistically control neurulation and segmentation of paraxial mesoderm in mouse embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Behavioral abnormalities of Zic1 and Zic2 mutant mice: implications as models for human neurological disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic2 patterns binocular vision by specifying the uncrossed retinal projection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic2 regulates retinal ganglion cell axon avoidance of ephrinB2 through inducing expression of the guidance receptor EphB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

A role for Zic1 and Zic2 in Myf5 regulation and somite myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

"Bent-Tail," A Dominant, Sex-Linked Mutation in the Mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

SoxD: an essential mediator of induction of anterior neural tissues in Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Gli/Zic factors pattern the neural plate by defining domains of cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Role of BMP, FGF, calcium signaling, and Zic proteins in vertebrate neuroectodermal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Mutations in the BMP pathway in mice support the existence of two molecular classes of holoprosencephaly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

BMP inhibition initiates neural induction via FGF signaling and Zic genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Calcium signalling during neural induction in Xenopus laevis embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Calcium transients triggered by planar signals induce the expression of ZIC3 gene during neural induction in Xenopus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Xenopus Meis3 protein lies at a nexus downstream to Zic1 and Pax3 proteins, regulating multiple cell-fates during early nervous system development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Low-complexity regions within protein sequences have position-dependent roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Understanding synergy in genetic interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Characterization of the interactions of human ZIC3 mutants with GLI3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

The Pluripotency Regulator Zic3 Is a Direct Activator of the Nanog Promoter in ESCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on protein-DNA interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Xenopus Zic3 controls notochord and organizer development through suppression of the Wnt/β-catenin signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Identification of a novel role of ZIC3 in regulating cardiac development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic1 regulates the patterning of vertebral arches in cooperation with Gli3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

EMAGE mouse embryo spatial gene expression database: 2010 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1285-5

Mouse Zic1 is involved in cerebellar development

21 January 2018

1 reference

12 December 2020

Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube.

1 reference

12 December 2020

Opl: a zinc finger protein that regulates neural determination and patterning in Xenopus.

1 reference

12 December 2020

A morphological and experimental study of the mesencephalic neural crest cells in the mouse embryo using wheat germ agglutinin-gold conjugate as the cell marker

1 reference

12 December 2020

Imaging patterns of calcium transients during neural induction in Xenopus laevis embryos.

1 reference

12 December 2020

From VACTERL-H to heterotaxy: variable expressivity of ZIC3-related disorders

1 reference

12 December 2020

Heterosis and variability in the mouse

1 reference

12 December 2020

1 reference

12 December 2020

The interfrontal bone and mutant genes in the mouse

1 reference

12 December 2020

A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice

1 reference

12 December 2020

A deletion encompassing Zic3 in bent tail, a mouse model for X-linked neural tube defects

1 reference

12 December 2020

10.1007/S00018-013-1285-5

Identifiers

DOI

1 reference

21 June 2017

1 reference