(Q30429015)

English

Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice (English)

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

atherosclerosis

1 reference

based on heuristic

inferred from title

Jason Lee Johnson

object named as

Jason L Johnson

3

0 references

7

object named as

Gary K Owens

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

author name string

Matthew R Alexander

1

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Christopher W Moehle

2

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Zhengyu Yang

4

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Jae K Lee

5

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Christopher L Jackson

6

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

language of work or name

0 references

publication date

27 December 2011

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

122

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

70-79

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Effects of interleukin-1 receptor antagonist on tumor stroma in experimental uveal melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Genomic profiling of tumor necrosis factor alpha (TNF-alpha) receptor and interleukin-1 receptor knockout mice reveals a link between TNF-alpha signaling and increased severity of 1918 pandemic influenza virus infection

1 reference

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20 June 2018

Actual status of antiinterleukin-1 therapies in rheumatic diseases

1 reference

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20 June 2018

The IL-1 family: regulators of immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Inflammation in atherosclerosis: from pathophysiology to practice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Alternatively activated macrophages in infection and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Immune and inflammatory mechanisms of atherosclerosis (*)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Soluble N-cadherin overexpression reduces features of atherosclerotic plaque instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Cellular and molecular mechanisms of fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Developmental basis of vascular smooth muscle diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Do metalloproteinases destabilize vulnerable atherosclerotic plaques?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Cytokines in atherosclerosis: pathogenic and regulatory pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Carotid atherosclerotic plaques in patients with transient ischemic attacks and stroke have unstable characteristics compared with plaques in asymptomatic and amaurosis fugax patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Divergent effects of matrix metalloproteinases 3, 7, 9, and 12 on atherosclerotic plaque stability in mouse brachiocephalic arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Pathophysiology of coronary artery disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

The chemokine system in diverse forms of macrophage activation and polarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Morphological predictors of arterial remodeling in coronary atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

The thin-cap fibroatheroma: a type of vulnerable plaque: the major precursor lesion to acute coronary syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

The good smooth muscle cells in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Arterial remodeling in atherosclerosis, restenosis and after alteration of blood flow: potential mechanisms and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Fibrous cap formation or destruction--the critical importance of vascular smooth muscle cell proliferation, migration and matrix formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Screening of ruptured plaques in patients with coronary artery disease by intravascular ultrasound

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Clinically stable angina pectoris is not necessarily associated with histologically stable atherosclerotic plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Chronic treatment with interleukin-1 beta induces coronary intimal lesions and vasospastic responses in pigs in vivo. The role of platelet-derived growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

20 June 2018

MMP-3 (5A/6A) polymorphism does not influence human smooth muscle cell invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Chronic Apoptosis of Vascular Smooth Muscle Cells Accelerates Atherosclerosis and Promotes Calcification and Medial Degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Pathological mechanisms and dose dependency of erythrocyte-induced vulnerability of atherosclerotic plaques.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Inhibition of progression and stabilization of plaques by postnatal interferon-gamma function blocking in ApoE-knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Smooth muscle cells in atherosclerosis originate from the local vessel wall and not circulating progenitor cells in ApoE knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Volumetric quantitative analysis of tissue characteristics of coronary plaques after statin therapy using three-dimensional integrated backscatter intravascular ultrasound

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Presence of intraplaque hemorrhage stimulates progression of carotid atherosclerotic plaques: a high-resolution magnetic resonance imaging study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Intracellular IL-1 receptor antagonist type 1 inhibits IL-1-induced cytokine production in keratinocytes through binding to the third component of the COP9 signalosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Interleukin-1 receptor signaling mediates atherosclerosis associated with bacterial exposure and/or a high-fat diet in a murine apolipoprotein E heterozygote model: pharmacotherapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Leukocyte-derived interleukin 10 is required for protection against atherosclerosis in low-density lipoprotein receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Lack of interleukin-1 receptor antagonist modulates plaque composition in apolipoprotein E-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Intraplaque hemorrhage and progression of coronary atheroma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Determination of the cholesterol-collagen ratio of arterial atherosclerotic plaques using near infrared spectroscopy as a possible measure of plaque stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Characteristics of intact and ruptured atherosclerotic plaques in brachiocephalic arteries of apolipoprotein E knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Serial volumetric intravascular ultrasound assessment of arterial remodeling in left main coronary artery disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Vulnerable plaque. Relation of characteristics to degree of stenosis in human coronary arteries.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage, and smooth muscle cell content

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248279

26 November 2018

Differential role and tissue specificity of interleukin-1α gene expression in atherogenesis and lipid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix Metalloproteinase (MMP)-3 Activates MMP-9 Mediated Vascular Smooth Muscle Cell Migration and Neointima Formation in Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase deficiencies do not impair cell-associated fibrinolytic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of transcription factor NF-kappaB reduces matrix metalloproteinase-1, -3 and -9 production by vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-18/Interleukin-18 Binding Protein Signaling Modulates Atherosclerotic Lesion Development and Stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between coronary artery remodeling and plaque vulnerability

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of matrix-metalloproteinase 3 found in coronary lesion samples retrieved by directional coronary atherectomy to intravascular ultrasound observations on coronary remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta mediates balance between inflammation and fibrosis during plaque progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expansive remodeling is a response of the plaque-related vessel wall in aortic roots of apoE-deficient mice: an experiment of nature

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of Interleukin-1β Decreases the Severity of Atherosclerosis in ApoE-Deficient Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of gelatinase a suppresses smooth muscle cell invasion and development of experimental intimal hyperplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagen types I and III, collagen content, GAGs and mechanical strength of human atherosclerotic plaque caps: span-wise variations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta in coronary arteries of patients with ischemic heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory cytokines cause coronary arteriosclerosis-like changes and alterations in the smooth-muscle phenotypes in pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein E-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stromelysin-1 (MMP-3)-independent gelatinase expression and activation in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of arterial geometry to luminal narrowing and histologic markers for plaque vulnerability: the remodeling paradox

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective Role of Interleukin-10 in Atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compensatory response of IL-1 gene knockout mice after pulmonary infection with Klebsiella pneumoniae

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type I IL-1 receptor mediates IL-1 and intracellular IL-1 receptor antagonist effects in skin inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22201681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI43713

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

ResearchGate publication ID

0 references

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