(Q30429540)

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Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder.

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28 February 2020

Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder (English)

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28 February 2020

Kerry J. Ressler

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28 February 2020

Torsten Klengel

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28 February 2020

Charles Gillespie

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28 February 2020

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28 February 2020

Tanja Jovanovic

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Tanja Jovanovic

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28 February 2020

Seth Davin Norrholm

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28 February 2020

Kristina B Mercer

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Kristina B Mercer

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28 February 2020

Elisabeth Binder

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Elisabeth Binder

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28 February 2020

Kimberly A Kerley

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Kimberly Kerley

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28 February 2020

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Karen Conneely

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28 February 2020

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Alicia K Smith

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28 February 2020

Jennifer S Davis

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28 February 2020

Jennifer Winkler

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28 February 2020

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10 April 2013

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28 February 2020

Frontiers in Behavioral Neuroscience

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28 February 2020

7

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28 February 2020

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28 February 2020

Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood

1 reference

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20 June 2018

Estrogen levels are associated with extinction deficits in women with posttraumatic stress disorder

1 reference

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20 June 2018

Children under stress - COMT genotype and stressful life events predict cortisol increase in an acute social stress paradigm.

1 reference

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20 June 2018

Effects of COMT polymorphisms on brain function and behavior in health and disease

1 reference

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20 June 2018

Attention bias toward threat is associated with exaggerated fear expression and impaired extinction in PTSD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622057

20 June 2018

Neural mechanisms of impaired fear inhibition in posttraumatic stress disorder

1 reference

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20 June 2018

Determination of Methylated CpG Sites in the Promoter Region of Catechol-O-Methyltransferase (COMT) and their Involvement in the Etiology of Tobacco Smoking

1 reference

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20 June 2018

PTSD and gene variants: new pathways and new thinking.

1 reference

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20 June 2018

The catechol-O-methyltransferase gene: its regulation and polymorphisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622057

20 June 2018

Catechol-O-methyltransferase (COMT) val158met polymorphism as a risk factor for PTSD after urban violence

1 reference

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20 June 2018

Fear extinction in traumatized civilians with posttraumatic stress disorder: relation to symptom severity

1 reference

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20 June 2018

How the neurocircuitry and genetics of fear inhibition may inform our understanding of PTSD.

1 reference

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20 June 2018

Impaired fear inhibition is a biomarker of PTSD but not depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622057

20 June 2018

Fear potentiation is associated with hypothalamic-pituitary-adrenal axis function in PTSD

1 reference

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20 June 2018

The risk of posttraumatic stress disorder after trauma depends on traumatic load and the catechol-o-methyltransferase Val(158)Met polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622057

20 June 2018

Genetics of PTSD: Fear Conditioning as a Model for Future Research

1 reference

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20 June 2018

Genetics of anxiety and trauma-related disorders

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20 June 2018

Neural substrates of pleiotropic action of genetic variation in COMT: a meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622057

20 June 2018

Posttraumatic stress disorder may be associated with impaired fear inhibition: relation to symptom severity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622057

20 June 2018

Timing of extinction relative to acquisition: a parametric analysis of fear extinction in humans.

1 reference

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20 June 2018

Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults

1 reference

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20 June 2018

Presence and acquired origin of reduced recall for fear extinction in PTSD: results of a twin study

1 reference

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20 June 2018

The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults.

1 reference

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20 June 2018

Genetics of posttraumatic stress disorder: Review and recommendations for future studies

1 reference

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20 June 2018

Epigenetic regulation in psychiatric disorders

1 reference

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20 June 2018

Conditioned fear extinction and reinstatement in a human fear-potentiated startle paradigm

1 reference

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20 June 2018

Contingency awareness and fear inhibition in a human fear-potentiated startle paradigm

1 reference

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20 June 2018

Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622057

20 June 2018

The effects of catechol O-methyltransferase genotype on brain activation elicited by affective stimuli and cognitive tasks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622057

20 June 2018

Catechol-O-methyltransferase val158met genotype affects processing of emotional stimuli in the amygdala and prefrontal cortex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622057

20 June 2018

Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622057

20 June 2018

The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes

1 reference

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20 June 2018

Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex

1 reference

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20 June 2018

Lymphocytes as a neural probe: potential for studying psychiatric disorders

1 reference

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20 June 2018

Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function

1 reference

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The role of DNA methylation in mammalian epigenetics

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20 June 2018

Dopamine transporter immunoreactivity in monkey cerebral cortex: regional, laminar, and ultrastructural localization

1 reference

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20 June 2018

Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior

1 reference

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Influence of brain-derived neurotrophic factor and catechol O-methyl transferase polymorphisms on effects of meditation on plasma catecholamines and stress.

1 reference

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26 November 2018

Stress-related methylation of the catechol-O-methyltransferase Val 158 allele predicts human prefrontal cognition and activity.

1 reference

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26 November 2018

Variation in genes involved in dopamine clearance influence the startle response in older adults.

1 reference

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Genetic gating of human fear learning and extinction: possible implications for gene-environment interaction in anxiety disorder

1 reference

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26 November 2018

COMT genetic variation affects fear processing: psychophysiological evidence

1 reference

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26 November 2018

COMT genotype predicts cortical-limbic D1 receptor availability measured with [11C]NNC112 and PET.

1 reference

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26 November 2018

Catechol O-methyltransferase val158met genotype and neural mechanisms related to affective arousal and regulation

1 reference

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26 November 2018

Association between the COMT Val158Met polymorphism and propensity to anxiety in an Australian population-based longitudinal study of adolescent health

1 reference

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Site-specific cytosine methylation in S-COMT promoter in 31 brain regions with implications for studies involving schizophrenia

1 reference

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26 November 2018

The association between panic disorder and the L/L genotype of catechol-O-methyltransferase

1 reference

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26 November 2018

Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation

1 reference

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26 November 2018

Catechol-o-methyltransferase (COMT) and proline dehydrogenase (PRODH) mRNAs in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and major depression.

1 reference

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26 November 2018

Genetic origins of anxiety in women: a role for a functional catechol-O-methyltransferase polymorphism

1 reference

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26 November 2018

Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter.

1 reference

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26 November 2018

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10.3389/FNBEH.2013.00030

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Europe PubMed Central

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28 February 2020

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Europe PubMed Central

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28 February 2020

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Europe PubMed Central

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28 February 2020

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