(Q30430077)

6 November 2017

Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells (English)

1 reference

6 November 2017

1 reference

5

Samson Amos

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20667897

12 June 2024

author name string

Benjamin Kefas

1

1 reference

6 November 2017

Laurey Comeau

2

1 reference

6 November 2017

Nicholas Erdle

3

1 reference

6 November 2017

Emmitt Montgomery

4

1 reference

6 November 2017

Benjamin Purow

6

1 reference

6 November 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20667897

12 June 2024

publication date

28 July 2010

1 reference

full work available at URL

6 November 2017

https://academic.oup.com/neuro-oncology/article-pdf/12/11/1102/3936376/noq080.pdf

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20667897

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20667897/pdf/?tool=EBI

12 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20667897

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20667897/?tool=EBI

12 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20667897

https://europepmc.org/articles/PMC3098027

12 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20667897

https://europepmc.org/articles/PMC3098027?pdf=render

12 June 2024

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20667897

https://doi.org/10.1093/neuonc/noq080

12 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20667897

http://academic.oup.com/neuro-oncology/article-pdf/12/11/1102/3936376/noq080.pdf

12 June 2024

1 reference

DOI

10.1093/NEUONC/NOQ080

https://api.crossref.org/works/10.1093/NEUONC/NOQ080

12 June 2024

1 reference

6 November 2017

12

1 reference

6 November 2017

11

1 reference

6 November 2017

1102-1112

1 reference

describes a project that uses

6 November 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3098027/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Pyruvate kinase M2 is a phosphotyrosine-binding protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

A microRNA component of the p53 tumour suppressor network

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Dual antiglioma action of metformin: cell cycle arrest and mitochondria-dependent apoptosis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

miRNAs, cancer, and stem cell division

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Pyruvate kinase type M2 and its role in tumor growth and spreading

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

miRNAs on the move: miRNA biogenesis and the RNAi machinery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

MicroRNA-directed cleavage of HOXB8 mRNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

TSC2 mediates cellular energy response to control cell growth and survival

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Oncogenic alterations of metabolism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Metabolic characteristics of different malignant cancer cell lines.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Association of the src-gene product of Rous sarcoma virus with a pyruvate-kinase inactivation factor.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Adenosine triphosphate conservation in metabolic regulation. Rat liver citrate cleavage enzyme

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

Double role for pyruvate kinase type M2 in the expansion of phosphometabolite pools found in tumor cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098027

The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity

20 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FNEUONC%2FNOQ080

Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNEUONC%2FNOQ080

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNEUONC%2FNOQ080

AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNEUONC%2FNOQ080

Adenosine triphosphate conservation in biosynthetic regulation. Escherichia coli phosphoribosylpyrophosphate synthase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20667897

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A control analysis exploration of the role of ATP utilisation in glycolytic-flux control and glycolytic-metabolite-concentration regulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20667897

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Critical Reviews in Oncogenesis

16

3

91

Eigenbrodt

1992

1 reference

DOI

10.1093/NEUONC/NOQ080

https://api.crossref.org/works/10.1093/NEUONC/NOQ080

12 June 2024

Identifiers

DOI

10.1093/NEUONC/NOQ080

1 reference

6 November 2017

1 reference

6 November 2017

1 reference