(Q30430349)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Cdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Zhigang Xie

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Karl R. Clauser

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

12

Li-Huei Tsai

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

author name string

Susan C Su

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Jun Gao

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Nadine Joseph

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Ying Zhou

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Omer Durak

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Lei Zhang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

J Julius Zhu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Steven A Carr

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

language of work or name

English

0 references

publication date

30 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

page(s)

e25735

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

14 February 2020

copyright license

start time

30 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3184170/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

HDAC2 negatively regulates memory formation and synaptic plasticity.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Changes in neuronal excitability serve as a mechanism of long-term memory for operant conditioning

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Critical role of CDK5 and Polo-like kinase 2 in homeostatic synaptic plasticity during elevated activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Cdk5 phosphorylation of doublecortin ser297 regulates its effect on neuronal migration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

A mouse model of Rubinstein-Taybi syndrome: defective long-term memory is ameliorated by inhibitors of phosphodiesterase 4

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Cdk5-Mediated Inhibition of the Protective Effects of Transcription Factor MEF2 in Neurotoxicity-Induced Apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Requirement for hippocampal CA3 NMDA receptors in associative memory recall

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress: differential roles of CRF receptors 1 and 2

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Translocation of calmodulin to the nucleus supports CREB phosphorylation in hippocampal neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Ameliorating effects of rolipram on experimentally induced impairments of learning and memory in rodents.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Subregion- and cell type-restricted gene knockout in mouse brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Postsynaptic cAMP pathway gates early LTP in hippocampal CA1 region

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Place navigation impaired in rats with hippocampal lesions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Potential antidepressant activity of rolipram and other selective cyclic adenosine 3′,5′-monophosphate phosphodiesterase inhibitors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

The Drosophila learning and memory gene rutabaga encodes a Ca2+calmodulin-responsive adenylyl cyclase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

A family of human cdc2-related protein kinases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory.

20 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025735

Impairment of hippocampal long-term depression and defective spatial learning and memory in p35 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025735

Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025735

Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025735

Temporally controlled targeted somatic mutagenesis in the mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025735

A vector for expressing foreign genes in the brains and hearts of transgenic mice

21 January 2018

2 references

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025735

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/21984943

12 December 2020

inferred from PubMed ID database lookup

Developmental expression of the prion protein gene in glial cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025735

Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025735

Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic capture

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025735

CDK5 serves as a major control point in neurotransmitter release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025735

A critical role of the nitric oxide/cGMP pathway in corticostriatal long-term depression.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Behavioral genetics: subregion- and cell type-restricted gene knockout in mouse brain.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184170

Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity

26 November 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025735

Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21984943

12 December 2020

inferred from PubMed ID database lookup

Involvement of pre- and postsynaptic mechanisms in posttetanic potentiation at Aplysia synapses

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21984943

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0025735

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21984943%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference