(Q30432390)

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Asparagine substitution at PB2 residue 701 enhances the replication, pathogenicity, and transmission of the 2009 pandemic H1N1 influenza A virus

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scholarly article

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Europe PubMed Central

PMC publication ID

17 August 2017

Asparagine substitution at PB2 residue 701 enhances the replication, pathogenicity, and transmission of the 2009 pandemic H1N1 influenza A virus (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

pathogen transmission

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influenza A virus

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influenza A virus

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based on heuristic

inferred from title

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Bin Zhou

1

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David E. Wentworth

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David E Wentworth

7

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Terrence M Tumpey

6

object named as

Terrence M Tumpey

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Melissa B Pearce

2

object named as

Melissa B Pearce

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Europe PubMed Central

PMC publication ID

17 August 2017

author name string

Yan Li

3

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Europe PubMed Central

PMC publication ID

17 August 2017

Jieru Wang

4

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Europe PubMed Central

PMC publication ID

17 August 2017

Robert J Mason

5

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Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

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publication date

14 June 2013

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Europe PubMed Central

PMC publication ID

17 August 2017

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Europe PubMed Central

PMC publication ID

17 August 2017

8

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Europe PubMed Central

PMC publication ID

17 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

e67616

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

copyright license

Creative Commons CC0 License

14 June 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

1 reference

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20 June 2018

Engineering temperature sensitive live attenuated influenza vaccines from emerging viruses

1 reference

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20 June 2018

Innate immune response of human alveolar macrophages during influenza A infection

1 reference

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20 June 2018

Pathogenesis and transmission of swine origin A(H3N2)v influenza viruses in ferrets

1 reference

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20 June 2018

Influenza research database: an integrated bioinformatics resource for influenza research and surveillance.

1 reference

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20 June 2018

Effect of D222G mutation in the hemagglutinin protein on receptor binding, pathogenesis and transmissibility of the 2009 pandemic H1N1 influenza virus

1 reference

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20 June 2018

Viral replication and innate host responses in primary human alveolar epithelial cells and alveolar macrophages infected with influenza H5N1 and H1N1 viruses

1 reference

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20 June 2018

A single base-pair change in 2009 H1N1 hemagglutinin increases human receptor affinity and leads to efficient airborne viral transmission in ferrets

1 reference

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20 June 2018

Impact of amino acid mutations in PB2, PB1-F2, and NS1 on the replication and pathogenicity of pandemic (H1N1) 2009 influenza viruses

1 reference

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20 June 2018

Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus

1 reference

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20 June 2018

Innate immune response to influenza A virus in differentiated human alveolar type II cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683066

20 June 2018

PB2 residue 158 is a pathogenic determinant of pandemic H1N1 and H5 influenza a viruses in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683066

20 June 2018

NS-based live attenuated H1N1 pandemic vaccines protect mice and ferrets

1 reference

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20 June 2018

Biological and Structural Characterization of a Host-Adapting Amino Acid in Influenza Virus

1 reference

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20 June 2018

The PB2-E627K mutation attenuates viruses containing the 2009 H1N1 influenza pandemic polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683066

20 June 2018

Pathogenicity of highly pathogenic avian H5N1 influenza A viruses isolated from humans between 2003 and 2008 in northern Vietnam

1 reference

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The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon

1 reference

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Substitution of lysine at 627 position in PB2 protein does not change virulence of the 2009 pandemic H1N1 virus in mice

1 reference

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20 June 2018

Introduction of virulence markers in PB2 of pandemic swine-origin influenza virus does not result in enhanced virulence or transmission.

1 reference

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20 June 2018

Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host

1 reference

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Adaptive strategies of the influenza virus polymerase for replication in humans

1 reference

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20 June 2018

Single-reaction genomic amplification accelerates sequencing and vaccine production for classical and Swine origin human influenza a viruses.

1 reference

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20 June 2018

Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice

1 reference

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Emergence and pandemic potential of swine-origin H1N1 influenza virus

1 reference

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Unraveling the mystery of swine influenza virus

1 reference

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Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic

1 reference

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Selection of H5N1 influenza virus PB2 during replication in humans

1 reference

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Differentiated human alveolar type II cells secrete antiviral IL-29 (IFN-lambda 1) in response to influenza A infection

1 reference

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Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N.

1 reference

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Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus

1 reference

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The influenza virus resource at the National Center for Biotechnology Information

1 reference

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Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit

1 reference

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Differentiated human alveolar epithelial cells and reversibility of their phenotype in vitro

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Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

1 reference

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1 reference

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1 reference

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Attenuation of equine influenza viruses through truncations of the NS1 protein

1 reference

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1 reference

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A single amino acid in the PB2 gene of influenza A virus is a determinant of host range.

1 reference

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The molecular basis of the pathogenicity of the Dutch highly pathogenic human influenza A H7N7 viruses

1 reference

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21 January 2018

Reverse genetics plasmid for cloning unstable influenza A virus gene segments

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0067616

21 January 2018

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10.1371/JOURNAL.PONE.0067616

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Europe PubMed Central

PMC publication ID

17 August 2017

2013PLoSO...867616Z

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24 November 2022

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Europe PubMed Central

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17 August 2017

PubMed publication ID

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Europe PubMed Central

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17 August 2017

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