(Q30432971)

4 November 2017

Practical and theoretical considerations in study design for detecting gene-gene interactions using MDR and GMDR approaches (English)

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4 November 2017

1

1 reference

4 November 2017

Yi Xu

2

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4 November 2017

Hai-Ming Xu

3

1 reference

4 November 2017

Ming D Li

4

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4 November 2017

Jun Zhu

5

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4 November 2017

Xiang-Yang Lou

6

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4 November 2017

language of work or name

English

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publication date

28 February 2011

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4 November 2017

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4 November 2017

6

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4 November 2017

2

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4 November 2017

e16981

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Creative Commons Attribution 4.0 International

4 November 2017

start time

28 February 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

Bayes' theorem

1 reference

18 June 2022

https://europepmc.org/article/PMC/3046176

inferred from PubMed Central ID database lookup

cites work

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Gene-gene interactions lead to higher risk for development of type 2 diabetes in an Ashkenazi Jewish population

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Common genetic variation and human traits

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Genomic convergence to identify candidate genes for Alzheimer disease on chromosome 10.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

What can genome-wide association studies tell us about the genetics of common disease?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Heritability in the genomics era — concepts and misconceptions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

A new multipoint method for genome-wide association studies by imputation of genotypes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

The effect of reduction in cross-validation intervals on the performance of multifactor dimensionality reduction.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

The challenge for genetic epidemiologists: how to analyze large numbers of SNPs in relation to complex diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

A role for CETP TaqIB polymorphism in determining susceptibility to atrial fibrillation: a nested case control study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

GPNN: power studies and applications of a neural network method for detecting gene-gene interactions in studies of human disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

A novel method to identify gene-gene effects in nuclear families: the MDR-PDT.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

The interaction of four genes in the inflammation pathway significantly predicts prostate cancer risk

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Traversing the conceptual divide between biological and statistical epistasis: systems biology and a more modern synthesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Gene-environment interactions in human diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Detecting epistatic interactions contributing to quantitative traits

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

The Ubiquitous Nature of Epistasis in Determining Susceptibility to Common Human Diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Power and design considerations for a general class of family-based association tests: quantitative traits

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Power calculations for a general class of family-based association tests: dichotomous traits

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

A perspective on epistasis: limits of models displaying no main effect

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

A combinatorial partitioning method to identify multilocus genotypic partitions that predict quantitative trait variation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Power studies for the transmission/disequilibrium tests with multiple alleles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

The future of genetic studies of complex human diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Epistasis and the release of genetic variation during long-term selection.

20 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

Concordance of multiple analytical approaches demonstrates a complex relationship between DNA repair gene SNPs, smoking and bladder cancer susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

Embryonic-endometrial interactions at implantation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

Single and multigenic analysis of the association between variants in 12 steroid hormone metabolism genes and risk of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

An association study of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

Estimating the power of variance component linkage analysis in large pedigrees.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

A general and accurate approach for computing the statistical power of the transmission disequilibrium test for complex disease genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

Power calculations for a general class of tests of linkage and association that use nuclear families with affected and unaffected sibs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

Bayesian inference of epistatic interactions in case-control studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus.

21 January 2018

2 references

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016981

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Ideal discrimination of discrete clinical endpoints using multilocus genotypes.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046176

Multilocus analysis of hypertension: A hierarchical approach

26 November 2018

1 reference

12 December 2020

Interaction of genetic risk factors confers higher risk for thrombotic stroke in male Chinese: a multicenter case-control study

1 reference

12 December 2020

Log-linear model-based multifactor dimensionality reduction method to detect gene gene interactions

1 reference

12 December 2020

Genomewide association studies--illuminating biologic pathways

1 reference

12 December 2020

Study of genegene interactions for endophenotypic quantitative traits in Chinese asthmatic children

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0016981

Identifiers

DOI

1 reference

4 November 2017

0 references

1 reference

4 November 2017

PubMed publication ID

21386969

1 reference