(Q30433183)

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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells

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scholarly article

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Europe PubMed Central

PMC publication ID

21 August 2017

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells (English)

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Europe PubMed Central

PMC publication ID

21 August 2017

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B-cell lymphoma

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diffuse large B-cell lymphoma

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Brian D Peyser

24

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Bryan T Mott

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object named as

Adam Yasgar

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Ajit Jadhav

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27

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Anton Simeonov

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21 August 2017

Christopher P Austin

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Christopher P Austin

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Craig J. Thomas

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Craig J Thomas

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ORCID Public Data File 2021

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Wenwei Huang

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Andrew Paul Shinn

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Paul Shinn

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Ganesha Rai

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Christopher A LeClair

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Christopher A Leclair

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Jian-kang Jiang

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Jian-Kang Jiang

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Lesley Mathews Griner

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Lesley A Mathews Griner

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Rajarshi Guha

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Ryan M Young

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Jonathan M Keller

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Dongbo Liu

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Ian S Goldlust

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Crystal McKnight

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Matthew B Boxer

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Damien Y Duveau

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Sam Michael

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Tim Mierzwa

14

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Martin J Walsh

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Paresma Patel

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William Leister

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David J Maloney

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Scott E Martin

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Marc Ferrer

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Louis M Staudt

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publication date

27 January 2014

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21 August 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

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21 August 2017

111

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21 August 2017

6

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21 August 2017

2349-2354

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21 August 2017

Targeting pathological B cell receptor signalling in lymphoid malignancies

1 reference

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ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

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20 June 2018

Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) has significant activity in patients with relapsed/refractory B-cell malignancies

1 reference

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Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma

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Critical role of PI3K signaling for NF-kappaB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells.

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Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity

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CAL-101, a p110delta selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability

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Oncogenic activation of NF-kappaB.

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12 December 2020

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10.1073/PNAS.1311846111

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Europe PubMed Central

PMC publication ID

21 August 2017

2014PNAS..111.2349M

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

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Europe PubMed Central

PMC publication ID

21 August 2017

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